David Sloane

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David Sloane

David Sloane

@dsloaned

analyzing DNA at @NucleusGenomics | prev. @cambreanHQ (acq’d)

New York City شامل ہوئے Ocak 2017
653 فالونگ828 فالوورز
David Sloane ری ٹویٹ کیا
Merriam-Webster
Merriam-Webster@MerriamWebster·
'St. Paddy's Day' is usually preferred over 'St. Patty's Day.' 'Paddy' is the shortened form of the original Irish spelling of 'Patrick,' which is 'Pádraig.' 'Patty' is the shortened form of 'Patricia.'
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Shane Curran
Shane Curran@arcurn·
Today, we’re excited to announce @Evervault's $25M Series B, led by Ribbit Capital with continued support from @sequoia, @IndexVentures, @kleinerperkins, and @nextplayVC. This round comes at a time when sensitive data exchange on the web is going parabolic. Since 2019, we’ve been focused on building durable infrastructure for engineering teams to collect, process, share, and enrich sensitive data -- while keeping it encrypted at all times. We thought we were making good progress in encrypting the web, helping customers like @tryramp, @Rippling, @finix, @TheOverwolf, @Uniswap, @CarTrawler, and hundreds of others secure more than $5bn/year in payment flows and 100m+ unique tokens per month. But the past year has shown that our enemy -- plaintext data -- is getting stronger and more pervasive. Our vision is to build the clearinghouse for sensitive data, helping companies exchange sensitive data in a secure and encrypted way. This round helps us encrypt more of the web by further refining our developer experience, building deeper integrations with trusted third-parties, and increasing the value we can offer our customers for more data types. First and foremost, thank you to our customers. You trusted Evervault to sit directly in the flow of your most sensitive data (payments, identity, financial information, and more) and that trust is not something we take lightly. Your feedback, your requirements, and the problems you bring to us every day are what shape the product and push us forward. Thank you to the Evervault team. What you’ve built is genuinely special: infrastructure that lets developers process sensitive data without ever having to see it in plaintext. The pace, craft, care, and ambition you bring to work every day are what makes this company what it is. And thank you to our new investors for believing in the vision of making security architectural rather than procedural. We’re grateful to have partners who understand both the scale of the problem and the opportunity ahead. The internet still assumes that sensitive data must exist in plaintext somewhere. We’re building the infrastructure to change that. Onwards! More here 👉 evervault.com/blog/series-b?…
Shane Curran tweet media
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Matteo Franceschetti
Matteo Franceschetti@m_franceschetti·
Today we're announcing a new round of funding that values @eightsleep at $1.5 billion, led by @tether Investments. Ten years ago I started Eight Sleep with one conviction: the night is the most underutilized lever in human health. Almost nobody was engineering their sleep. Last year, we hit free cash flow positivity, launched 3 new products, expanded to 34 countries, and published peer-reviewed studies showing the Pod reduces menopausal hot flashes by 56% and restores the body's natural circadian temperature rhythm during sleep, lowering core body temperature and improving cardiovascular recovery. A product you sleep on is producing clinical outcomes that rival pharmaceutical interventions. We're now building a predictive AI agent trained on 1B+ hours of sleep data. It anticipates your night before it happens. And we're advancing FDA filings for sleep apnea detection. Passive. Every night. No wires, no clinic visits. The night is just the beginning.
Matteo Franceschetti tweet media
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David Sloane
David Sloane@dsloaned·
@Alicebentinck the competition isn’t the co’s in your space though - it’s every company ~10 co’s generate +90% of all returns in venture for the year
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Alice Bentinck
Alice Bentinck@Alicebentinck·
I often hear European founders and VCs say the reason not to go to the US is that it's too competitive. What I now realise is that is the reason to go to the US. The competition makes everyone 100x better.
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Emmanuel Macron
Emmanuel Macron@EmmanuelMacron·
In France, we believe in science. That is why, on May 5, I issued a clear and open call to the world: for science, choose France. I am very proud to see that this call has resonated so strongly. Around forty leading researchers have chosen France. Through “France 2030”, we have invested more than €30 million to advance health, climate action, artificial intelligence, and fundamental sciences. Science has found its home.
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David Sloane
David Sloane@dsloaned·
David Sloane tweet media
Kian Sadeghi@KianSadeghi5

Everything levied unto Nucleus by @sichuan_mala is false. Worse than false, it appears to be architected by a competitor that has repeatedly published misstatements and inaccuracies. Sichuan is compromised. But it gets worse. I have been informed that @cremieuxrecueil — race “scientist” in chief — has been paid off by the competitor to promote this nonsense against Nucleus. For the independent scientists repeating this libel, I would encourage you to do more diligence on who you are aligning yourself with. Our scientific team will issue a point by point response. Unfortunately, though, this isn’t about science. It’s a concerted attempt to cancel Nucleus on the backs of our successful campaign and efforts to build + advance the industry, which benefits the very people who are attacking us. To the the mob trying to cancel Nucleus: Keep tweeting. Stay mad. We’ll keep building and serving patients. P.S. We won the injunction. Link below.

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Stephan Cordogan
Stephan Cordogan@stephan_cdgn·
I'm the lead author on Nucleus Origin. All substantive technical claims about the Nucleus Origin preprint made by @sichuan_mala are false. I outline why, point-by-point, in the link below.
Stephan Cordogan tweet media
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David Sloane
David Sloane@dsloaned·
Will — you and many others are piling on without knowing 1% of the backstory. We’ve dealt with this pattern every time: the same anonymous accounts, the same suspects, the same coordinated noise. The meme was a joke about that, not our scientific stance. You can find the receipts here - scordogan.substack.com/p/setting-the-… (with lot’s of substance). We’re aware of the fact that we’re selling a scientific product, you don’t have to remind us.  Our model weights have been public to anyone, including competitors, for over a month. No other company in the space comes close to this level of transparency. You can download them and investigate yourself.
will o’brien@Willob

David, I am sorry now man, but you guys are doing an absolutely terrible job at responding to this blog post & seem to be missing the point here first of all, it is a huge claim to say that every claim made by @sichuan_mala is false with absolutely zero evidence or explanation. show receipts. second of all, you make the claim that that person is paid off by a competitor of yours, again with zero evidence. thirdly, you make the claim that @cremieuxrecueil is paid off by your competitor. this is totally bogus and not true. but most importantly, you guys have made zero points of substance here rather than just insinuating you guys are leaping ahead and others are jealous (which is what this picture is insinuating). man, you are selling a scientific product and someone has made a scientific critique (in good faith, waiting to be corrected and explicitly saying they will make changes if they are proved wrong) and the best you guys can do is accuse them of being "paid off" and reply with memes -- not a great look Look, I want to see startups with a bold vision succeed, but how you communicate with the broader world is so important, especially with a product like yours & how you guys are carrying on in this is honestly pretty lacklustre

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Kian Sadeghi
Kian Sadeghi@KianSadeghi5·
BREAKING Have your best baby. Today, @nucleusgenomics announces the largest genetic optimization campaign ever. > Full station-blitz of Broadway Lafayette > 1,000+ street ads across NYC > 1,000+ subway car ads > Dozens of Urban panels throughout Soho
Kian Sadeghi tweet media
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Nucleus Genomics
Nucleus Genomics@nucleusgenomics·
Anyone can have a taller, smarter, and healthier baby with IVF+. But the broader public is not yet aware what is now possible with advanced genetics. So we've launched the "Have Your Best Baby" campaign to bridge that gap. The future of modern family planning is here.
Nucleus Genomics tweet media
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Kian Sadeghi
Kian Sadeghi@KianSadeghi5·
Big news: Nucleus is going global. We’re expanding our mission to make genetic optimization accessible to everyone, starting with a groundbreaking partnership with CdelaF that will transform reproductive medicine in Mexico. Through Nucleus IVF+, families in Mexico can now access advanced reproductive genetics — from carrier screening to embryo analysis — without ever leaving the country. Together, we’re bringing the future of reproductive health to more people, helping families make informed choices and give every child the best possible start in life.
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Stephan Cordogan
Stephan Cordogan@stephan_cdgn·
I’m thrilled to have led efforts to develop Nucleus Origin, the most predictive family of PRS to-date, explaining over 20% of liability-scale variance in Alzheimer's, coronary artery disease, prostate cancer, type 1 and type 2 diabetes!
medRxiv@medrxivpreprint

Within- and Between-Family Validation of Nine Polygenic Risk Scores Developed in 1.5 Million Individuals: Implications for IVF, Embryo Selection, and Reduction in Lifetime Disease Risk medrxiv.org/cgi/content/sh… #medRxiv

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Kian Sadeghi
Kian Sadeghi@KianSadeghi5·
AI can now predict your future — before you’re born. @nucleusgenomics just launched Origin, disease models trained on 1.5M genomes combining 7M genetic markers. Origin predicts human longevity from embryo DNA more accurately than any model ever built. And it’s open-weighted.
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