Craig A Townsend

97 posts

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Craig A Townsend

Craig A Townsend

@CATLab20

advances in natural products chemistry, biology and their relation to medicine; and a laboratory to do great science

Tham gia Ocak 2021
50 Đang theo dõi353 Người theo dõi
Stephen Fried JHU
Stephen Fried JHU@fried_lab·
My promotion and #tenure is now official @JohnsHopkins. Just feeling really happy and grateful for my students, colleagues, family, and friends. You've made the last 7 years in #Baltimore some of the best in my life! 😁
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Craig A Townsend
Craig A Townsend@CATLab20·
Yesterday Stevie Wonder received an Honorary degree from Hopkins and the Peabody, and gave us a song to a cheering ovation. The genius of his name is correct.
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Craig A Townsend
Craig A Townsend@CATLab20·
Former Group Member Brenda Wilson was in town to receive an award from the @ASMicrobiology as her highly regarded "Bacterial Pathogenesis: A Molecular Approach " heads to a new edition. We posed for a picture with her pbk for non-experts written with her son! How cool is that?
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Yang Yang
Yang Yang@yang2biocat·
We publish our second paper on pyridoxal biocatalysis in Nature: We repurposed PLP-dependent threonine aldolases to catalyze radical C-C coupling reactions that are not known in either organic chemistry or enzymology: nature.com/articles/s4158…
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Piel Lab
Piel Lab@piel_lab·
Congrats to @AnnaVagstad bringing this amazing story to the finish line! Thank you to everyone involved from @BroderickLabFeS for the fantastic collaboration! If you are interested in the enzymatic mechanism of peptide epimerization by rSAM, make sure to read it.👇
J. Am. Chem. Soc.@J_A_C_S

📷 Detection of the α-Carbon Radical Intermediate Formed by OspD: Mechanistic Insights into Radical S-Adenosyl-l-methionine Peptide Epimerization |Journal of the American Chemical Society @montanastate #Radical #Detection #OspD #SAM #Peptide #Epimerization pubs.acs.org/doi/10.1021/ja…

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Craig A Townsend
Craig A Townsend@CATLab20·
Year-End Kudos. Especially to former Group member Doug Cohen and his team mates at Vertex for seeing thru to FDA approval the first CRISPR-based therapy for a genetic disorder— sickle cell disease‚ a landmark. Congratulations and to all who have made advances in 2023
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Yi Tang
Yi Tang@yitang_ucla·
I am honored to be the new Editor-in-Chief for @SIMB_Microbio society journal JIMB. Our open access journal has a wide scope covering different areas of biotechnology. We look forward to working with you to publish your latest research results! ⚡️⚡️ academic.oup.com/jimb
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Craig A Townsend
Craig A Townsend@CATLab20·
@piel_lab @Microbio_ETH Congratulations Joern! May it be the first of many happy reunions. It's as much for your inspired and grateful students as for you to see each other again.
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Piel Lab
Piel Lab@piel_lab·
What a great day we had yesterday! Thank you so much to everyone who joined the 10-year anniversary (in person and remote) of our lab being @Microbio_ETH. It was so heartwarming to see where life took former lab members and great to connect former and current #pielies.
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Craig A Townsend đã retweet
JACS Au
JACS Au@JACS_Au·
We are delighted to announce the 2023 JACS Au Early Career Advisory Board! Each year, we appoint new members to this board, seeking perspectives from, and providing advice and guidance to, emerging independent scholars. Check out the list: go.acs.org/5lW
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Nicole M. Gaudelli
Nicole M. Gaudelli@NicoleGaudelli·
I’ve always enjoyed working along the interface of chemistry and biology and here I report my second natural product total synthesis: Isabella Ruth 💕 born May 20th, 2023.
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Nicole M. Gaudelli
Nicole M. Gaudelli@NicoleGaudelli·
Why is it that when there are difficult decisions to make, people often choose unhappiness over uncertainty? I have found that taking the uncertain path has typically led to the greatest yields in happiness over time. Hard choices, easy life. Easy choices, hard life.
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Craig A Townsend
Craig A Townsend@CATLab20·
Appearing today in @J_A_C_S. Connecting the dots to a biogenetic proposal for anthraquinone-fused enediyne biosynthesis: doi.org/10.1021/jacs.3… Remarkable rearrangement and oxidation chemistry — and a simple, efficient synthetic model. Congratulations Paramita and Serena!
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Craig A Townsend
Craig A Townsend@CATLab20·
@jjanetzko @J_A_C_S There is a lot to appreciate in the syntheses of KCN, SJD and AGM and now to contrast a greatly different concept and solution emerging from the shadows by the GOAT natural product chemist. Thanks for seeing.
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John Janetzko
John Janetzko@jjanetzko·
@CATLab20 @J_A_C_S My PhD advisor studied calicheamicin for her PhD work, and KCN’s synthesis of it is still one of my favourites in this book he signed for me 😍
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