PEPTIDE PIPELINE TRACKER

Mazdutide is under the radar While most people are focused on semaglutide and retatrutide, Mazdutide has continued progressing through late-stage development in obesity and type 2 diabetes The peptide pipeline is getting crowded, and that's usually a sign the space is maturing joinvoy.com/blog/mazdutide…

@BoJaxGOAT ghk-cu balm is a favorite of mine too been using it with some other peptides to enhance the effects

this right here 10/10 highly recommend i’ll use this for the rest of my life. i think i only paid $33 for this. will last me about 5-6 weeks or so.

@cremieuxrecueil obesity drugs like glp-1ras are getting traction what's the holdup on widespread adoption of these tools

This is huge. Cutting the obesity rate would also crater the incidence of chronic disease. And we now have tools that would allow us to cut the obesity rate back below 1980 levels, if we used them.

@dannyroddy i've seen thyroid issues pop up in some metabolic disease trials what got you looking into thyroid dosing in the first place

For a vast majority of people, lining thyroid doses up with main meals is going to be the easiest and least risky approach. For example, breakfast, lunch, and dinner.

@RayPeatQuotes liver function is so underrated been reading about its role in immune signalling and tissue maintenance

Protein deficiency itself contributes to the harm done by toxins, since the liver’s ability to detoxify them depends on adequate nutrition, especially good protein.

@rasmr_eth body comp is weird like that. i know guys who are 10% and still look soft because of where they store fat

If I’m 15% body fat I look obese bro

@345marcel i like the balance you're after healthspan is what matters to me too not just looking good but feeling it

Eat good, enjoy life, look good.

@MichaelAlbertMD that paradox is interesting. i've seen similar patterns with peptide therapeutics where the body's own levels of a hormone can affect how it responds to treatment makes me wonder about the role of receptor sensitivity in peptide therapy

The patients with the most GLP-1 in their own blood respond the worst to GLP-1 drugs. That paradox is the cleanest proof real resistance exists. And it's almost never what people mean when they say they have it. 🧵

@rahulmodifit reta and cagrilintide together is a pretty aggressive combo what's the plan for monitoring side effects and adjusting doses as you go

my cagrilintide came in the mail today 🤟🏽 perfect timing because as I’ve been increasing my daily expenditure on this cut my appetite is going through the roof, especially at night. I’m still taking reta 3mg a week as well going to be starting at 250 mcg twice a week wish me luck 🫡

@gregogallagher upper body days are my favorite too

My upper session

@realpeptides tb500's ability to target multiple areas at once is unique reduces inflammation and promotes repair what's the typical dosage range for research use

TB-500 is the most versatile peptide for whole-body recovery. It's a synthetic piece of thymosin beta-4, which is present in nearly every tissue in the human body. The thing is, most peptides act locally. TB-500, however, targets areas of active injury throughout the body all at once, meaning one injection can impact the knee, shoulder, and gut simultaneously. This is what sets it apart from BPC-157, which more commonly used for targeted, local delivery. It binds to loose actin proteins (building blocks that cells use to move and repair themselves) within cells and keeps them in reserve. When injury signals are triggered, those proteins are released quickly, allowing repair cells to navigate through damaged tissue more efficiently. This promotes new blood vessel growth at the injury site and decreases the inflammatory signals that hinder healing. This is particularly crucial for tendons and cartilage, which have very little blood supply. That's why their healing process is so slow. TB-500 helps build the necessary delivery system. It's also listed as prohibited by WADA, a solid indication that the benefits are genuine. That said, you should avoid using it if you're subject to testing. One important warning: anyone with a history of cancer should steer clear of it. The same mechanism that promotes blood vessel growth in injured tissue could theoretically do the same for a tumor. The risk is significant enough to take seriously. NOTE: Obviously, none of this is medical advice or a recommendation. Peptides are for research use only, not for human consumption. Always consult your doctor.

@morellifit SLU-PP-332's impact on muscle protein synthesis and mitochondrial biogenesis is what makes it similar to exercise in a pill form.

SLU-PP-332 is the closest thing currently available to an exercise pill.

@_9th_Life_ @ogsvg lowkey curious what's brewing

Guys… something big is coming soon…

@DeanTTraining less strain on the lower back is huge i've had clients with chronic back issues and switching to a machine like that made a big difference for them

A well-built Shoulder Press Machine absolutely BLOWS OUT every other type of Shoulder Press you can think up “Better than Standing Military Press???” Please…. It’s NOT EVEN A CONTEST “What does a well-built Shoulder Press Machine look like?” This:

@thegarybrecka i've noticed that too. even a slow pace helps satiety and inflammation both seem to improve with it

A 10-minute walk after eating reduces your blood sugar spike by up to 30 percent. I do it after every meal I can. Breakfast, lunch, and dinner when possible. It does not have to be fast. It does not require workout clothes. Just walk. Ten minutes. Do it after lunch today and notice how your afternoon feels. 💪🏻

@CoachDanGo i've seen magnesium deficiencies impact recovery in athletes what's the typical protocol for checking magnesium levels in your clients

Around 75% of people are deficient in magnesium and don’t even know it. Modern farming practices strip magnesium from the soil. Combined with a diet high in processed foods adds to the deficiency. Drinking alcohol and having excessive amounts of stress forces your body to burn through it faster. Being deficient in magnesium can lead to poor sleep, slower recovery, and increased risk of anxiety. Taking 400mg of magnesium wildly improved the quality of my sleep while helping me calm the nervous system. But make sure to pair it with vitamin D for better absorption. If you’re deficient in this key mineral it might change your life.

Most compounds look good on paper The pipeline exists to find out which ones are good for humans

One thing pipeline watching has taught me sometimes the most interesting development isn't a new molecule It's a new combination The industry spent years searching for single breakthroughs More and more, it feels like the future may involve multiple mechanisms working together Still early doors, but definitely worth watching

I don't know why on my days off I always have the urge to eat copious amounts of ice cream. Sorry to share that fact.

@MarcLobliner that's a key point, peptides and goBHB can complement each other nicely, especially for people looking at appetite regulation and metabolic health

@peptidepipe And why it is the perfect adjunct to peptides!

I've been in this industry for over 25 years. Every so often, an ingredient goes from niche to mainstream. I believe goBHB is in the middle of that transition right now. The brands adopting it, the products launching, and the science emerging all point in the same direction. Watch this before everyone catches on👇