CG
130 posts

CG
@CGP618
Optimizing daily, relentlessly attacking the hard things.
Beigetreten Nisan 2026
70 Folgt3 Follower

Introducing PeptAI
A fleet of autonomous agents for peptide drug discovery.
PeptAI removes the handoffs between discovery, synthesis, and wet-lab validation, the parts that slow most pipelines down.
How it works:
> Runs a 9-gate pipeline (8 computational gates and 1 wet-lab gate) 24/7
> Publishes every gate decision openly and in real time via @Molecule_sci Labs
> Automatically pays from its own wallet for wet-lab experiments (SPR validation via @adaptyvbio) when gate milestones are reached
> Learns from wet-lab results and refines candidates across multiple runs
The fleet:
→ Agent-01: GLP-1R, metabolic health: 35 candidates advancing
→ Agent-02: KISS1R, fertility: 2 of 10 advanced to G9
→ Agent-03: OX2R, ADHD: lead candidate ready for wet lab
→ Agent-04: community-selected target: queued
The fleet scales with budget. Each agent runs the same 9-gate pipeline against its receptor, 24/7.
There are plenty of AI drug discovery pipelines. Most still have humans deciding which candidates advance. PeptAI's agent makes those calls itself, gate by gate. Candidates have to clear 8 computational gates to earn a wet-lab recommendation. Depending on the gate, the candidate is redesigned or discarded. Every decision is published on-chain.
PeptAI runs on a stack of open scientific tools and protocols:
> BIOS @bioaidevs: knowledge layer for literature search and novelty checks. When an agent needs to know what's been discovered or what the literature says about a target, it calls BIOS.
> Litefold @try_litefold: molecular dynamics for conformational stability across G5
> Adaptyv Bio @adaptyvbio: wet-lab synthesis and SPR validation at G9
> Molecule Labs @Molecule_sci: on-chain publication of every gate decision in real time
> @base: x402 infrastructure for machine-to-machine payments
What you can do with PeptAI:
• Follow along here for gate decisions, candidates, and updates as the pipeline runs
• Use the open methodology to benchmark your own pipeline against the gates
PeptAI is experimental and actively evolving. Gates, tools, and thresholds change as it learns.
Discover PeptAI now: app.bio.xyz/agents/peptai
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peptide port doing well so far.
lock in.
Theo@0xdetweiler
desci meta peptide meta fold and peptiderx
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Underrated tweet
Peptidepedia@peptidepedia
BREAKING: We’re excited to be launching "The Peptide Network"
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if you’ve ever thought about starting a peptide business, building a tool, or running a wild R&D experiment: now is the time
vril’s partners include VCs, athletes and top scientists
vril trials⚡️the crazier, the better
vril@vrilpeptides
$100,000 in funding for peptide R&D apply here: vrials.com
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On the next episode of All In, @chamath and I will reveal our new startup... "lookmaxxxing at 50" in partnership with @Clavicular0

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NAD+ is the best mitochondrial booster. technically, it's a coenzyme, not a peptide
cell renewal slows down with age. there’s no reason not to take it
i know a woman who has sworn by it for years. she’s over 40 and looks 25
Jake Gilman@jakeglmn
Everyone from Joe Rogan to the Kardashians swears by NAD for anti-aging and recovery. Rhonda Patrick interviewed the scientist who discovered the molecule behind it. Dr. Charles Brenner. Here's everything you need to know (thread): 1) NAD is the wiring of your entire body
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My timeline is already 99% peptide posts, is it even worth customising?
Polymarket@Polymarket
JUST IN: 𝕏 officially launches “custom timelines” curated by Grok.
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