Andrew the Embryologist

Thanks everyone participated in this edition of #ESHREjc 🤩 Big applause to our experts 👏🏼👌🏻🙏@AndrewIVFSAS @alteri_ale @debsmtj & Alison Campbell for their insightful contributions @ESHRE

#ESHREjc Q2. Authors have found an effect on clinical outcomes when double biopsy 🧬🧬 and double ❄️❄️ was performed. 🌀What are the sources of amplification failure from a genetics🧬/embryological background❓️❓️ @ESHRE

Accurate data entry, reporting and publication is so hard to do in a single clinic never mind multiple clinics! Is there a way to make this more streamlined and efficient? #ESHREjc

@AndrewIVFSAS On the other hand, there are still too many protocol variations in how it is performed: pulling vs flicking, assisted hatching on day 3 vs day 5-6-7, and whether to wait for the TE to extrude or biopsy directly #ESHREjc

@alteri_ale @juanjo_fraire @GLiperis @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @debsmtj @AndrewIVFSAS Also, this is more achievable than assuming everyone will standardize their protocols unless there’s a regulatory body to mandate it! #eshrejc

@juanjo_fraire @GLiperis @OmarRawi89 @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @alteri_ale @debsmtj @AndrewIVFSAS The quality of the existing literature is also a matter of concern. From the 607 records the authors identified, 570 were initially excluded with a further 28 due to not meeting study requirements, resulting to a total of 9 studies with 3 being abstracts #ESHREjc

@juanjo_fraire @GLiperis @OmarRawi89 @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @debsmtj @AndrewIVFSAS Not all included studies adjusted for important patient-related factors (e.g., maternal age, embryo quality, prior ART outcomes), which may have influenced results #ESHREjc

Keep the conversation topic related and respectful please 👏🏼 Don’t forget to use the #ESHREjc in all your responses 🤩

#ESHREjc Q2. Authors have found an effect on clinical outcomes when double biopsy 🧬🧬 and double ❄️❄️ was performed. 🌀What are the sources of amplification failure from a genetics🧬/embryological background❓️❓️ @ESHRE

@cimsit @GLiperis @OmarRawi89 @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @alteri_ale @debsmtj @AndrewIVFSAS Yes! Standardization of lab protocols, data recording, data reporting and data publication are musts #ESHREjc 🤓

It gives me great pleasure to introduce our experts for this #ESHREjc @BasselWattar @alteri_ale @debsmtj @AndrewIVFSAS Balsam Hashimi Alison Campbell As well as moderators @OmarRawi89 @juanjo_fraire @SCobanMune @zoyaalii_ @kashish__ & authors @RuiWangMD Yanhe Liu