DRMP retweeté
latest from the lab --> how we used whole genome passenger somatic mutation patterns 🧬 to trace the origins of never-smoker lung adenocarcinoma (LUAD) to cells of the proximal lung 🫁 @NatureGenet nature.com/articles/s4158… 1/🧵
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DRMP
415 posts
DRMP
@DRMP2025
Assistant Prof @nyugrossman @Perlmutter_CC | Somatic mosaicism in cancer & aging 💻🔬 Opinions my own. Also at: https://t.co/au1Q3tFHF7
New York, USA Inscrit le Temmuz 2018
464 Abonnements1.3K Abonnés
Honored to be part of the 2025 class of #PackardFellows ✨ and deeply grateful to the Packard Foundation for supporting bold science that advances knowledge and real-world impact 🌎🧬🙏 packard.org/2025fellows
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@DRMP2025 Wonderful news… congrats Mia & Petljak lab!! 🚀
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Big, beautiful trees!!
SMART-PTA for whole-genome+transcriptome on thousand of single cells from the normal human esophagus 🤯 Massively scaling up the power of scWGS to build deep phylogenies and chart somatic evolution from birth throughout life.
biorxiv.org/content/10.110…
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@AACR Seeing friends and gushing about our shared love for DNA 🤓🧬😃🤟@TimCoorens @imartincorena @ivazquezgarcia #AACR25
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DRMP retweeté
Some trully trainee led science! @Elsa2Bernard @oriol_pich Maria Zagorulya - our work is done here!
Read how CH can influence solid tumor progression & treatment response ⬇️
@NEJM with the one & only @CharlesSwanton
@MSKCancerCenter @TheCrick
Oriol Pich@oriol_pich
🚨Thrilled to share our latest work: “Tumor-Infiltrating Clonal Hematopoiesis” @NEJM - we investigated how age-related blood mutations impact cancer when they infiltrate tumors, with @Elsa2Bernard Maria Zagorulya, @PapaemmanuilLab @CharlesSwanton + more nejm.org/doi/full/10.10…
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DRMP retweeté
Excited to share our exploration @naturemethods into new horizons opening up in the era of low cost sequencing!
🔥 Deeper sequencing at WGS scale for PPM sensitivity of tumor informed MRD
🔥Duplex sequencing at WGS scale for plasma only exploration of ctDNA
Check out thread 👇
Alexandre Pellan Cheng@AlexandrePCheng
What happens when sequencing costs go ⏬ ? Imagination and new opportunities go ⏫ @landau_lab Let's look at what you can do when you perform deep WGS on cfDNA for cancer detection. Our recent work with the @UltimaGenomics platform 🧵👇 Lets goooo!! rdcu.be/ehkUb
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🚨OPEN POSTDOC
POSITION in our brand new lab space by Madison Sq NYC ! 🌆🧬🔬
Do experiments, learn computation, and uncover drivers of a major mutational process affecting >50% of cancers, driving therapy resistance & impacting immunotherapy responses👇
#apobec" target="_blank" rel="nofollow noopener">med.nyu.edu/research/postd…
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DRMP retweeté
#mRNAvaccines for #PancreaticCancer (PDAC) PART4
1. Out today in @Nature nature.com/articles/s4158…
🧵👇🏽
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DRMP retweeté
Our paper on Ultra-Rapid ddPCR (15 min tissue to result somatic mutation quantification) is now in @MedCellPress. A wonderful collaboration with @DanOrringerMD that succeeded because of the intrepid work of @ZacharyR_Murphy, Emilia Bianchini, and the team. cell.com/med/abstract/S…
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👇breakthrough - non-opioid pain signaling inhibitor & first approved new class of pain medicine in >20 yrs 😮👏
Vertex Pharmaceuticals@VertexPharma
#Breaking: The U.S. FDA approves our treatment for moderate-to-severe acute pain in adults. This is the first new class of pain medicine to be approved in over 20 years. Learn more: news.vrtx.com/news-releases/…
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Several years in the making (and aging), @Xueqian_Zhuang 's study on aging is out today @Nature. She finds, surprisingly, that aging suppresses tumorigenesis and stemness in the lung by promoting a functional iron insufficiency in the alveolar epithelium. nature.com/articles/s4158…
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DRMP retweeté
1/ Introducing SCimilarity, a new foundation model to explore scRNAseq data across tissues and diseases! It learns a common measure of cell similarity by training a deep metric learning model on millions of cells from various human tissues and conditions. nature.com/articles/s4158…
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@S_J_Aitken @YaleCancer @yalepathology @aitken_lab @clarnedo @_HAN1999 @MRC_TU @Cambridge_SBS @Cambridge_Uni @YaleMed @MuschenLab @DrEricWiner @YaleGenetics Only seeing this now - congrats!!! And see you soon? :)
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It is official: My lab and I are moving to @YaleCancer Center in December! Very excited to be joining the Center of Molecular and Cellular Oncology and @YalePathology
Want to be part of @aitken_lab 2.0? We are hiring at all levels - so get in touch!
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Took a little maternity leave time to visit Rincon, Puerto Rico. 3 years and 2 babies later, still catching some waves 🏄🏻♀️. Reminding the importance of switching off, spending time with family & friends #QualityOfLifeImpactFactor 💯
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