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@DRMP2025

Assistant Prof @nyugrossman @Perlmutter_CC | Somatic mosaicism in cancer & aging 💻🔬 Opinions my own. Also at: https://t.co/au1Q3tFHF7

New York, USA Katılım Temmuz 2018
467 Takip Edilen1.3K Takipçiler
DRMP
DRMP@DRMP2025·
I’m incredibly grateful to @psscra for the Pershing Square Sohn Cancer Prize, recognizing our work and enabling an important part of our broader vision to develop personalized cancer prevention strategies 🙏
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Adam Rubin
Adam Rubin@adamjrubin·
Excited to share our paper out today in @ScienceMagazine! We directed high-content, single-cell genetic screens to ask how a disordered adapter protein orchestrates the complex process of T cell activation. (1/4) science.org/doi/10.1126/sc…
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Itai Yanai
Itai Yanai@ItaiYanai·
We're in this week's Nature! We propose a model of how a cell learns by running an evolutionary algorithm: exploring different gene-regulatory combinations and using feedback responses to stabilize those combinations that reduce stress levels. Full text: nature.com/articles/s4158…
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Anirban Maitra
Anirban Maitra@Aiims1742·
Only half of esophageal adenocarcinomas (EACs) are associated with background Barrett esophagus (BE). New integrated epidemiological & molecular data from @RFitzgerald_lab reinforces commonalities between the two reiterating that BE is universal precancer. nature.com/articles/s4159…
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Inigo Martincorena
Inigo Martincorena@imartincorena·
Excited to share our latest work. Applying advanced single-molecule and single-cell DNA sequencing methods, we uncover an extraordinary landscape of somatic mutations in immune checkpoint genes in autoimmune lymphocytes. [1/n] rdcu.be/fdqbr
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Marcin Imieliński
Marcin Imieliński@skimomiks·
latest from the lab --> how we used whole genome passenger somatic mutation patterns 🧬 to trace the origins of never-smoker lung adenocarcinoma (LUAD) to cells of the proximal lung 🫁 @NatureGenet nature.com/articles/s4158… 1/🧵
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DRMP
DRMP@DRMP2025·
Honored to be part of the 2025 class of #PackardFellows ✨ and deeply grateful to the Packard Foundation for supporting bold science that advances knowledge and real-world impact 🌎🧬🙏 packard.org/2025fellows
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DRMP@DRMP2025·
@landau_lab Huge - congrats Dan!! 🤩
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Dan Landau
Dan Landau@landau_lab·
Big, beautiful trees!! SMART-PTA for whole-genome+transcriptome on thousand of single cells from the normal human esophagus 🤯 Massively scaling up the power of scWGS to build deep phylogenies and chart somatic evolution from birth throughout life. biorxiv.org/content/10.110…
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Elli Papaemmanuil, PhD
Elli Papaemmanuil, PhD@PapaemmanuilLab·
Some trully trainee led science! @Elsa2Bernard @oriol_pich Maria Zagorulya - our work is done here! Read how CH can influence solid tumor progression & treatment response ⬇️ @NEJM with the one & only @CharlesSwanton @MSKCancerCenter @TheCrick
Oriol Pich@oriol_pich

🚨Thrilled to share our latest work: “Tumor-Infiltrating Clonal Hematopoiesis” @NEJM - we investigated how age-related blood mutations impact cancer when they infiltrate tumors, with @Elsa2Bernard Maria Zagorulya, @PapaemmanuilLab @CharlesSwanton + more nejm.org/doi/full/10.10…

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Dan Landau
Dan Landau@landau_lab·
Excited to share our exploration @naturemethods into new horizons opening up in the era of low cost sequencing! 🔥 Deeper sequencing at WGS scale for PPM sensitivity of tumor informed MRD 🔥Duplex sequencing at WGS scale for plasma only exploration of ctDNA Check out thread 👇
Alexandre Pellan Cheng@AlexandrePCheng

What happens when sequencing costs go ⏬ ? Imagination and new opportunities go ⏫ @landau_lab Let's look at what you can do when you perform deep WGS on cfDNA for cancer detection. Our recent work with the @UltimaGenomics platform 🧵👇 Lets goooo!! rdcu.be/ehkUb

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DRMP
DRMP@DRMP2025·
🚨OPEN POSTDOC POSITION in our brand new lab space by Madison Sq NYC ! 🌆🧬🔬 Do experiments, learn computation, and uncover drivers of a major mutational process affecting >50% of cancers, driving therapy resistance & impacting immunotherapy responses👇 #apobec" target="_blank" rel="nofollow noopener">med.nyu.edu/research/postd…
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