ArcellAI

179 posts

ArcellAI

ArcellAI

@ArcellAI

We’re building the agentic context layer for techbio + deep tech.

San Francisco, CA Bergabung Temmuz 2025
1 Mengikuti15 Pengikut
ArcellAI
ArcellAI@ArcellAI·
hey @AstasiaMyers @avelezarce here. your view on devtools starting with extreme single-player value + scaling to org-wide systems feels spot on, especially in complex AI infra. we’re building the agent-native context + execution layer for deploying AI in fragmented, multimodal systems (techbio, healthcare, engineering). not a copilot, the underlying infra that makes these systems actually work in production. we have early design partners with path to $200k+ ARR. curious if this resonates, worth a quick chat? deck: arcell.ai/deck memo: arcell.ai/founder-memo a@arcell.ai
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Astasia Myers
Astasia Myers@AstasiaMyers·
Hot take 🔥: AI coding agents are undermining the open source SaaS business model The moat was asymmetric complexity: clustering, autoscaling & HA cost $1M+ to build so buyers paid $200K/yr for a managed version AI collapses the build vs. buy calculus. Expect a shift back to open core, support & services
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ArcellAI
ArcellAI@ArcellAI·
hey @alexiskold @avelezarce here. given your focus on vertical AI, healthcare, and data systems of record at 2048, this may resonate. we’re building the agent-native context + execution layer for deploying AI in fragmented, multimodal environments (techbio, healthcare, engineering). not another copilot, the infrastructure that makes these systems actually work in production. we have early design partners with path to $200K+ ARR curious if this resonates, worth a quick chat? deck: arcell.ai/deck arcell.ai/founder-memo a@arcell.ai also - had a brief stint at @Techstars_NYC @Techstars :-)
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Alex Iskold | 2048.vc
Alex Iskold | 2048.vc@alexiskold·
We’ve @2048vc said this all along. Also system of engagement is system of action? But those all were never safe ever, because systems of record aka platforms would cherry pick best ones, and implement.
TBPN@tbpn

Sequoia's @gradypb says systems of record software companies are relatively safe from AI disruption, but that systems of engagement companies built on top of them are in trouble: "The first wave of the on-prem to cloud transition was transitioning systems of record — the Workdays, Salesforces, and Servicenows of the world." "The second layer on top of that was the systems of engagement. The systems of record might own the core database, but then there are a bunch of different workflow applications that reside on top." "I think what we're going to see with the wave of AI software is a third layer on top of those." "It's the layer that does the work. It's the agents getting deployed. They may or may not need those workflows beneath them, but certainly need access to everything that's sitting in that system of record." "As a result, I think those systems of record companies are relatively safe. They may not catch a lot of net new workloads, because those might go to the AI native companies. But I think overall they're pretty safe." "I think some of those workflow-based companies in the middle are in trouble, because they're neither the systems of record nor the agentic capability that's getting deployed. So they'll have to figure out how to become like that agent harness, so to speak, for whatever job needs to be done."

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ArcellAI
ArcellAI@ArcellAI·
hey @sarahcat21 @avelezarce here. you’ve spent your career at the intersection of AI, data infrastructure, and real-world deployment (palantir → amplify bio). we’re tackling the same core problem: models aren’t the bottleneck, infrastructure is. we’re building the agent-native context + execution layer for deploying AI across fragmented multimodal systems in techbio, healthcare, and engineering. feels highly aligned with your focus on data systems that actually work in production. curious if this resonates, worth a quick chat? deck: arcell.ai/deck arcell.ai/founder-memo a@arcell.ai
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Sarah Catanzaro
Sarah Catanzaro@sarahcat21·
Prompt engineering is so over. Context engineering is so over. Harness engineering is in. But you’re still trying to figure out where to place “do not lie” in context…
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ArcellAI
ArcellAI@ArcellAI·
@mil000 insider scoop: ceo's own admission, @ycombinator interview: "do you have a demo?" -> no "do you have customers?" -> no "how far along are you?" -> we've been experimenting with the idea "thanks" [same day]-> accept certain demographics: easy YC checks not serious investors.
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ArcellAI
ArcellAI@ArcellAI·
@rdominguezibar @avelezarce Also, we have an old open LinkedIn thread from an intro from Christy Cull! We were asked for a traction update from the speedrun team last year and have since achieved significant milestones!
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Ruben
Ruben@rdominguezibar·
I'd love to angel invest in a handful of startups this month. Pre-seed and seed. Ideally AI or VC-adjacent, but open to all. My value add: ▪️ 500K+ newsletter subscribers across The VC Corner and The AI Corner ▪️ 300K+ LinkedIn followers, 2–4M weekly impressions ▪️ a16z speedrun scout ▪️ Network of top VCs, operators and founders 👉 Pitch in comments
Ruben@rdominguezibar

the PITCH DECKS💰 that raised billions are now public. Study them before your next raise: 1️⃣ 26 pitch decks that raised $400M in 2026 → thevccorner.com/p/26-pitch-dec… 2️⃣ Anthropic's 2022 pitch deck just leaked: 10 slides, no product, now worth $380B → thevccorner.com/p/anthropic-20… 3️⃣ 16 unicorn pitch decks: the actual slides before the billions → thevccorner.com/p/unicorn-pitc… 4️⃣ Peter Thiel only explained once how to raise money. Here it is → thevccorner.com/p/peter-thiel-… 5️⃣ SpaceX: how to build and pitch the most ambitious company of our time → thevccorner.com/p/spacex-strat… 6️⃣ Synthesia turned down Adobe's $3B offer. Here's the 18-slide deck that raised $180M → thevccorner.com/p/inside-synth… 7️⃣ How Brex raised $57M and rebuilt startup banking → thevccorner.com/p/how-brex-rai… 8️⃣ 50 real pitch decks from startups that raised $380M+ → thevccorner.com/p/50-real-star… 9️⃣ 200+ pitch decks that raised over $50 billion → thevccorner.com/p/200-startup-… 🔟 153 startups fundraising right now with their actual decks → thevccorner.com/p/153-startups… Bookmark this. The best founders study what worked before they pitch. How much does a pitch deck actually matter vs the founder behind it?

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Alex Finn
Alex Finn@AlexFinn·
If you’re in college and none of your classes are teaching you Claude Code or OpenClaw, regardless of your major you need to drop out immediately.
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Guillermo Flor
Guillermo Flor@guilleflorvs·
🚨 BREAKING: I’m partnering with @deel to fund up to 10 founders with $1,000,000 🤑 Deel just launched The Pitch, a global startup tournament, for the best founder in the world, presented by J.P. MORGAN. The prizes: • 10 startups will each receive a $1M SAFE • 100 regional winners will each receive $50K SAFEs • $15M+ total capital deployed And we’re officially partnering with them to push this to the Market Fit audience 🔥 This isn’t a gimmick. It’s a real funding vehicle. Here’s how it works: 1️⃣ Submit a 5-minute application 2️⃣ Top startups get invited to regional in-person finals 3️⃣ Regional winners get funded 4️⃣ Global finalists compete for $1M Just product, team, and ambition. I know how cracked my founder audience is. If you’re building something serious, this is an asymmetric upside. Don’t worry, we’ll be spotlighting strong applications from our side 😉 I’ll personally be backing and pushing the strongest applications. Apply. Swing big. Let’s fund one of you! 𝗖𝗼𝗺𝗺𝗲𝗻𝘁 𝘆𝗼𝘂𝗿 𝗣𝗜𝗧𝗖𝗛 𝗮𝗻𝗱 𝗜’𝗹𝗹 𝘀𝗲𝗻𝗱 𝘆𝗼𝘂 𝘁𝗵𝗲 𝗹𝗶𝗻𝗸 🔥 PS: I'll review all comments tomorrow, don't miss the opportunity!
Guillermo Flor tweet media
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Thomas Massie
Thomas Massie@RepThomasMassie·
If America would embrace capitalism and reject cronyism in health care, agriculture, military contracting, insurance, media, technology, and banking, we would experience a renaissance unprecedented in human history.
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