Natoshi Sakamoto

@rwitoff What’s the Y axis in this plot?

In the last 12 months, we’ve seen a 27x increase in non-engineers using dev tools like Claude, OpenCode and Cursor to build & automate how we work. The goal is to turn everyone into a builder, and safely reduce the distance between idea → execution to near zero. Trust is our most important asset at @coinbase, so this is fueled by a massive effort in quality, guardrails and simplification.

@markkaplan20 “After my heart attack” “I take zero medications” Mutually exclusive statements.

I carry APOE ε3/ε4. My fasting insulin today is 3.7. Optimal. My HOMA-IR is 0.80. My hs-CRP is undetectable. My HbA1c is 5.4. My metabolic age is 43. I am 58. I take zero medications. My son David has the same gene. He is eating for his DNA at 21. His insulin is optimal. His inflammation is undetectable. Same gene. Different strategy. Different outcome. This is what I wish someone had told me at 40 instead of handing me a statin at 52.

I carry a gene that raises my risk of Alzheimer's by 40%. It is called APOE ε4. About 25% of people carry at least one copy. I have one. My son David has the same one. Nobody told me until I was 53. After my heart attack. After 12 years of annual physicals. The test costs $100. Once. For life.

@brian_armstrong Have you played Warcraft 3? If so, what race?

In my teens and 20's I would spend way too much time playing Starcraft and Civilization. Harvesting resources, building things, and expanding was super addictive to my brain - to an almost unhealthy degree. Later I realized that entrepreneurship and business is the ultimate game. It scratches the same itch for me (resources, building, expanding), but you're actually contributing to humanity at the end of the day, which can be much more fulfilling. Business is also much more positive sum than video games. In Starcraft, the other player has to lose for you to win. In business, there is competition, but in a growing market there can be multiple winners. And gains compound long term (it's a infinite game) instead of starting over each time. Now days I prefer to watch pros play video games to unwind, instead of playing video games myself. But a quick game can still be fun here and there to unwind. By contrast, the game of business is played over many decades.

@bryan_johnson Rotti or Dobbi

I'm thinking about getting two dogs. What breeds should I consider?

@LazyCharts @SolidTradesz 🎯

@SolidTradesz Top didn’t exactly look like the typical top. So I don’t think we need to get the typical bottom?

This is how a bottom for $BTC should look like We are not there yet 💀

@WatcherGuru Mfkr!!!

JUST IN: Jim Cramer says buyers will pump Bitcoin back to $82,000.

@PeterAttiaMD P for Peter or Per…

A closer look at the MET-PREVENT trial and what its null results reveal about aging interventions and trial design. Full article linked below. bit.ly/4tpASVs

@RayDalio “Freed from the constraints of the supply of tangible gold, silver, or some other hard asset (Bitcoin).”

Central banks want to stretch the money and credit cycle to make it last for as long as it can because that is so much better than the alternative. So when the system of hard money and claims on hard money becomes too painfully constrictive, governments typically abandon it in favor of what is called “fiat money.” No hard money is involved in fiat systems; there is just paper money that the central bank can print without restriction. As a result, there is no risk that the central bank will have its stash of hard money drawn down and have to default on its promises to deliver it. Rather, the risk is that, freed from the constraints on the supply of tangible gold, silver, or some other hard asset, the people who control the printing presses (i.e., the central bankers working with the commercial bankers) will create ever more money and debt assets and liabilities in relation to the amount of goods and services being produced until the time comes when those holding the enormous amount of debt will try to turn it in for goods and services, which will have the same effect as a run on a bank and result in either debt defaults or the devaluation of money. #principleoftheday

@minchoi How is this different from enterprise self-hosted Claude Code offered to devs in software companies?

Ok Clawdbot is insane. People can't stop building and founders are making money with it. 10 wild examples + how to setup (No-code required guide in ~30 minutes). Bookmark this👇

@DrProfitCrypto *if market allows to visit* my most favorite phrase of all X influencers.

Expecting targets for #BTC below 80k in the coming weeks! The crash will continue as promised in September! My shorts from 115-125k remain fully open and I have 12 orders prepared if market allows to visit: Short orders placed at: 97k, 98k, 99k, 102k, 104k, 105k, 106k and 107k

@BobLoukas @Crypto_McKenna Bob, could this set up the left translated cycle - blow off peak mania top 1st year followed by 3 yrs bear.

@Crypto_McKenna Agree.

If BTC breaks all time highs in 2026 and breaks the whole notion of the 4 year cycle then I believe this will trigger the peak euphoria event. This would be massive levels of speculation and things might get very stupid.

@bryan_johnson Please review Chipotle and Subway. Two of the most used fast food places for vegetarians!

I went to Taco Bell. Ordered their best selling products and assessed the ingredients. It's not a good situation. Worst part: our kids eat this😭. If we fail to become a Type III civilization on the Kardashev scale, I blame Taco Bell and similar.

@coinbureau That video was made right before October. @coinbureau I appreciate your content but please be up to date in tweets.

🔥BITCOIN STILL HAS A LONG WAY TO RUN Coinbase CEO Armstrong said: “There will never be more than 21 million Bitcoin in existence, and vast pools of capital still don’t have access to it. That tells me Bitcoin still has a long way to run.”

@workslikejenga @saylordocs He is just 28 yrs old bro

@saylordocs Grandpa unlocked generational wealth

This guy found an old Bitcoin wallet

@ecfholding @EzyBitcoin Yes 4H seems to be good lower timeframe for CrossX. Btw it has printed a TR & Sell on 4H few hours back, aren’t you not selling the rest at this point?

@EzyBitcoin I bougth at $86,820 using 4H and I just realized 50% at $93k and waiting the rest of my position to $100k. Thanks to provide that amazing indicator.

$BTC FULL UPDATE: IT LOOKS LIKE $BTC IS HEADING BACK TO $100K AGAIN. I’m not holding any positions at the moment since my last trade has already hit Take Profit. However, CrossX is still in buy mode, so I’ll be looking for another opportunity to go long. Currently, $BTC is forming a double bottom pattern, which is a reversal pattern from a downtrend to an uptrend. This pattern will be confirmed once the neckline around $93k is broken, with upside targets at $99k and $105k. The likelihood of a breakout at the $93k neckline is quite high since CrossX is still in buy mode and most of the signals on the dashboard in the bottom-right corner are bullish. However, if CrossX prints a sell signal, this plan will be canceled immediately. I’ll share the next signal with you for free as always if this post reaches 500 LIKES. Or you can access CrossX here: mycrossx.com/getcrossx Cheers!

@EzyBitcoin What timeframes do y”all find it useful? Of course W is the gold standard. D is kinda OK for trending direction. Do any smaller timeframes consistently produce no-fake signals?

Quick update: I’ve closed all my remaining $BTC long position at break even (around $88k) after took 50% profit at around $93k. Like & Retweet and I’ll share the next signal with you for free. Cheers!

@bryan_johnson Looks like more than one sin is committed here: Missed sleep regularity, skipped wind down routine, watched blue light, spent time on stimulating content (I love Dexter btw).

i'll start, i went to bed 64 minutes later than i should have last night because the family had to finish the 10th episode of dexter: resurrection

it's time to confess you dirty animals, what have you been up to this weekend?

@TedPillows 🔮

Where are we currently in this crypto cycle?

@RoundtableSpace 🤣

ChatGPT Bitcoin price predictions: One week from today: $110,200 One month from today: $118,600 One year from today: $176,000 Stop getting chopped up trading lower time frames. Stack as much BTC as you can and zoom out. Higher for longer.

@BobLoukas Or next cycle is left translated and blow off tops until OpenAI goes public.

You can’t top a bull market while OpenAI’s still yet to go public.