Alexander Talavera Karslake

@Valria34773 @sama You just confirmed your condition, well done!

Please show me your medical degree that authorizes you to diagnose strangers on the internet based on 3 sentences and 2 hashtags with a "condition" that is not even officially acknowledged and does not included in the DSM-5. I hope you know what DSM-5 is without googling it. And also if you are such an excellent mental health specialist, you should know that it is not ethical to diagnose anyone without in-person assessment. Guidelines like the APA's Goldwater rule explicitly bar diagnosing without an examination. Telehealth permits regulated remote video exams, but a real clinician-patient process remains essential. So can you please shut the fuck up retard and sit down? Go back to school little boy! #keep4o

still sorta breaks my brain to see our models be good at design finally

@RutgerMonty @MobofJoggers What a load of bs. Also, you're assuming that the human on the other side would continue course normally instead of trying to avoid you which would cause a head on collision. But yeah let's hate technology.

@MobofJoggers Not the choice I would have made - there was plenty of time (without spooking the other driver too much) to cross the oncoming lane and head for the grass shoulder on the left. But one caveat: if another car was following closely, then there's no hope for the dog.

Wow. FSD chooses between hitting a dog and hitting a car head on. This is an important but difficult video to watch. FSD makes the right choice!

@Valria34773 @sama lol still locked on a dumb ai model? really? 4o whatever get over it just because it was so sycophantic. You have AI psychosis.

@sama Sam, it's high time you consult your social media team. No, rather your therapist. What you are doing today is a clear sign of desperation. Too much scamming harms your health. #keep4o #BringBack4o

@thdxr This isn't vibecoded. I use AI to help me go faster in some cases (and slower in others, because AI)

@thdxr apps.apple.com/fr/app/ahorita…

please i'm begging you show me something you built not another "this is my custom agent setup" post where you pretend you're doing something smarter than vanilla claude code please

@Digitalformedx @SawyerMerritt Sure, my genius keyboard warrior

No more Tesla vehicles from that plant? I thought the Teslas were selling out faster than they could make them. And the robots are going to be bought up by who? Again, Elon better hire a million techs to fix those robots as the training is going to take a while and once the robots go world wide and there are no repair shops around, people will be pissed off wanting their money back. So now all the IT guys and engineers have to retrain for the new robotist tech jobs.

Tesla has released a new video of them tearing down the Model S and Model X production lines at Fremont ahead of the installation of the Optimus lines. When fully ramped, this space will be able to produce 1 million Optimus robots per year.

@DennisWhit73777 @Rainmaker1973 No. Cartilage doesn't grow back. Hence the news.

@Rainmaker1973 When your cartilage wears out between your bones it then grows back eventually, and that's when you get bone spurs cause it does not grow back smooth.

A new shot literally regrows knee cartilage. Researchers at Stanford Medicine have identified a novel strategy to regenerate articular cartilage in knees and potentially prevent or treat osteoarthritis (OA). The method targets 15-hydroxyprostaglandin dehydrogenase (15-PGDH), an age-related enzyme—or "gerozyme"—that accumulates in aging tissues and drives degeneration. In aged mice, small-molecule inhibitors of 15-PGDH, delivered systemically or via intra-articular injection, promoted cartilage thickening and regeneration of functional hyaline articular cartilage. This occurred without recruiting stem or progenitor cells; instead, existing chondrocytes underwent transcriptional reprogramming to a youthful state, with reduced populations of inflammatory and hypertrophic/degradative cells and expanded matrix-producing articular chondrocytes. The inhibitors also reversed natural age-related cartilage thinning, improved joint function, and—when administered after simulated ACL injuries—strongly mitigated post-traumatic OA progression and associated pain. Human OA cartilage explants from total knee replacements responded similarly in vitro, showing decreased degradation markers and evidence of new articular cartilage formation. Given that an oral 15-PGDH inhibitor has already completed Phase 1 safety trials for age-related muscle atrophy, the findings open a path toward disease-modifying, regenerative therapies that could delay or obviate the need for joint replacement surgery. [Agarwal, P., Su, S., Ancel, S., et al. (2025). Inhibition of 15-hydroxy prostaglandin dehydrogenase promotes cartilage regeneration. Science. DOI: 10.1126/science.adx6649]

@LukeOtwell @mattpocockuk This won't age well

@mattpocockuk maybe talking about code will be something only low lifes do in 2 years.

I hate the phrase "code is cheap" so much ✅ Communicates that code has become cheaper to produce ❌ Implies that code is disposable, low worth, not worth caring about Code is the environment the agent operates in. Better code = better output

@jordanrstout @mattpocockuk I see your point but to be fair I've been following Matt since before the ai revolution, he's an excellent developer, independently from ai.

@mattpocockuk Everyone trusts the guy with the accent.

Folks who have adopted my skills at your org, I have a question for you: What was the thing that made people go "yes, let's do this"? What were its advantages over similar tools?

@PhuzzyBond @DataChaz Lol this wet way above your paygrade lol. You would need to specify in which axis and that could still be misinterpreted.

@DataChaz The real prompt is "Rotate the Knife 90 Degrees"

Vibe coders’ daily struggles, summed up in 60 seconds 😁

@RunescapeSuxs @thatsarix @WindowsLatest Lol, no.

@thatsarix @WindowsLatest Disagree. AI codes better than humans nowadays

Microsoft says it'll replace the ancient Windows 11 dialog box with a modern rewrite (WinUI) in a major design update. Microsoft confirmed that the company is working through older Windows dialogs and rewriting them in WinUI 3. The file copy dialog is already done internally, and the common file dialog is on the list. That matters because Windows 11 still feels split between two eras. Some parts look modern, while basic dialogs still feel like they were pulled from decades-old Windows code. The good news is this is not just “dark mode.” Microsoft is actually rebuilding these surfaces in WinUI. The concern, of course, is performance. WinUI has not always been fast. But Microsoft says the new Run dialog opens faster than the legacy one, with a 94ms median time-to-show versus 103ms for the old version. That is the right direction. Modern UI is fine, but only if it stays fast.

@shariar_design @BrettFromDJ 🤢🤮🤢🤮

creator @BrettFromDJ

If this is what AI can already do, design today is a waste of time 😭

@shariar_design Disgusting behaviour of yours, stealing from others and taking their credit. Everyone should block this account immediately.

@emollick I played it, it's trash. Just a bunch of divs, nothing of movement, is this what we call a game? Also it auto scrolls up every time I select something. It's just walls of text. And all the AI comments here make me want to puke.

Here Opus 4.8 built and play-tested a new RPG in Claude Code, including 3 PDF manuals and adventures, playtest notes, a website, and a playable solo adventure - then put it all on Netlify. No feedback from me at all. stillpoint-osr.netlify.app

@JohnnyParker This is excellent. Thanks John gonna super charge my business

Wapisimo.dev Human Behavior Today we're happy to announce the launch of a feature many have been asking for, and which no other Whatsapp API offers: optional human-like behaviors to avoid bans Natural Mode is out now and included in ur already dirt-cheap subscription

@AG25561 @histories_arch @archeohistories Idiot

@histories_arch @archeohistories Biological adaptation is NOT evolution, it's just adaptation! If evolution was true, birds could also become fish and homosapiens could also become apes. Definition of evolution is the gradual process of change and development over time not species changing into another species.

Evolution is often thought of as a process that took millions of years, shaping life in the distant past. But scientists are now proving that evolution isn’t just history, it’s happening all around us, right in the present. Species continue to adapt, survive, and change in response to their environment, offering living proof that evolution is very much real. One striking example comes from the world of microbes. Bacteria can evolve in days or weeks, developing resistance to antibiotics at astonishing speed. This rapid adaptation highlights the ongoing struggle for survival and the remarkable flexibility of life. But it’s not just microbes showing evolutionary change, plants and animals are evolving too. In some species of birds, changes in beak size and shape have been observed over just a few decades, adapting to shifts in available food sources. Insects are developing new patterns of resistance to pesticides, and urban animals like city-dwelling foxes and pigeons are evolving behaviours and physical traits to thrive alongside humans. Even marine life is changing, with some fish populations adapting to warmer waters caused by climate change. These examples remind us that evolution is not a static concept but a continuous process shaping life every day. It demonstrates the power of natural selection and adaptation, showing that species are never truly “finished.” Instead, life constantly experiments, survives, and transforms in response to challenges. Some species of fish in lakes have developed new generations that can hatch eggs faster to avoid being eaten, essentially rewriting their life cycles in real time. © The PreHistoric World

@levelsio @Airbnb Airbnb sucks. I stick to booking.com

Same, I really don't like @Airbnb after booking my last one in Brazil I used the shower for 3 minutes and it was already flooding, so I told the host, who started blaming me for it Then contacted Airbnb Support, who called us etc. Then in the end the host gave me a bad review with fake made up shit, and Airbnb wouldn't let us post a review about the host! Just speechless really

@MissKhan2092520 @Patrickwebb ☪️ an☪️ er

@Patrickwebb I finally able to escape from my home country to the US because of violence against me and my family. Now you want me to go back??

BREAKING: The Trump admin announces that all green card applicants must leave the country indefinitely, regardless of whether they are in the U.S. legally or have spouses or children who are citizens, per NY Post.

@pgerrits @rezoundous Exactly.

@rezoundous Meh. You always have to think, what are these tasks? What are these people building? A to-do app? Yeah, it is fine. A website? Yeah, it's fine. A warehouse management system... no

Is Composer 2.5 really that good at coding? Anyone tried it yet?

@rezoundous From my tests, and they weren't super exhaustive, it failed at things that I then asked gpt5.5 to fix which it did kind of well. No model produces great code, but as long as things aren't too complex and you don't let them create 2k+ lines of code files, all is well.