Drew Nelson
994 posts
Drew Nelson
@Andrew_TNelson
PhD candidate in @chemical_phd studying gene editing @liugroup (He/Him)
Katılım Nisan 2012
369 Takip Edilen222 Takipçiler
Drew Nelson retweetledi
Today in @Science_Magazine we report the laboratory evolution of compact degrons that enable targeted protein degradation triggered by an otherwise-inert small molecule, a multidisciplinary study that integrates organic chemistry, molecular glues, protein evolution, genome editing, and structural biology.
PDF: drive.google.com/file/d/18hu15h…
1/13
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Drew Nelson retweetledi
I’m thrilled to share the results from the first project of my PhD! Huge thanks to my co-authors @NeugMonicaElena and @NicholasKrasnow for their contributions and support throughout the project. Very excited to see how the community will use these next-generation base editors!
David R. Liu@davidrliu
Today we report in @NatureComms the development of laboratory-evolved CBE6 cytosine base editors that offer high on-target C•G-to-T•A editing, virtually no A•T-to-G•C editing, low off-target editing, broad sequence context compatibility, and compatibility with multiple Cas domains. /1
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Drew Nelson retweetledi
In the latest issue! Phage-assisted evolution and protein engineering yield compact, efficient prime editors dlvr.it/SvV693
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Drew Nelson retweetledi
Welcome @NeugMonicaElena on joining the UW–Madison Department of Biochemistry, and #UWMadisonChem as an affiliate faculty. Monica will arrive in late summer or early fall and we're excited to welcome her as the newest addition to a thriving Chemistry/Biochemistry team.
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Drew Nelson retweetledi
Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity bit.ly/3WO5QWX
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Drew Nelson retweetledi
A team of researchers led by Harvard and Broad Institute scientists has developed twin prime editing, a new gene-editing strategy hrvd.me/DNASegments23t
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Drew Nelson retweetledi
Very good news this morning👍👍
Exciting new data on Paxlovid anti-Covid pill from 2 randomized, placebo-controlled clinical trials: high-risk final results and standard (low) risk interim findings, summarized here. See @statnews full coverage by @matthewherper
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@WRgordonlab @umncbs Thanks Wendy!! I’m proud to rep the Gordon lab here😁 I’ve been missing the puns
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Wow!! Congrats on playing a role @LilGLeprechaun, @umncbs and Gordonlab alum! This is prime material for journal club next week! #gordonlabpuns
David R. Liu@davidrliu
Today we report in @NatureBiotech twin prime editing to make larger substitutions, insertions, & deletions. TwinPE + recombinases can make gene-sized (thousands of bases) precise insertions & inversions at sites of our choosing in human cells. Tweetorial👇🏼drive.google.com/file/d/1GQLxtk…
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Drew Nelson retweetledi
Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing go.nature.com/3EIt47c
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Drew Nelson retweetledi
CROWN HIM!
Corbin Burnes is your 2021 NL #CyYoung winner! He's the third Cy Young winner in franchise history.
@Burnes16 | #ThisIsMyCrew
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Drew Nelson retweetledi
SCOOP: The day after Columbine shootings, top NRA execs, PR experts, lobbyists scrambled on conference calls to strategize.
Over 2.5 hrs they laid out the playbook of the NRA after mass shootings for the next 20+ years.
I have the secret tapes.
npr.org/2021/11/09/104…
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@_BAnderson30_ might be my favorite @Brewers pitcher cuz he looks like they picked a random fan playing cornhole to join the team, and it turns out he’s good at throwing a ball.
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How my day was ruined before 9am:
propublica.org/article/the-se…
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@victor_gmiranda I was hoping for the ESPN-televised, 5-star recruit picking a ball cap kinda thing, but I’m still psyched for ya. Congrats!
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Super excited to announce that I've joined Andrew Kruse's lab at HMS as my PhD thesis lab. I'll be exploring therapeutic relevance of nanobodies targeting GPCR's. Today is my first day as an official member of the lab 👌
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I say the Packers double down and draft a backup QB for Love. Cut my life into pieces. This is my last resort.
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Drew Nelson retweetledi
This is good advice for all science.
Also the alt text: "We reject the null hypothesis based on the 'hot damn, check out this chart' test."
XKCD Comic@xkcdComic
Statistics xkcd.com/2400/ m.xkcd.com/2400/
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@StefanZukin @igisci Just when ya think it’s niche enough to give some job security...
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Elaine Paige. Cats. Playbill.
Tim Allen@ofctimallen
Carl Marx. Communist manifesto. Wikipedia.
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