Anna Molofsky

Highly dynamic dural sinuses support meningeal immunity @Nature @NIAIDNews nature.com/articles/s4158…

Our new book "Self-Doubt" is written by scientists for scientists. You might think you are alone when you doubt your ability or suitability for science - you aren't. We all question ourselves and carry doubt with us daily. amazon.com/Self-Doubt-Ant…

Thanks for the shoutout- we are excited to share this new sensitive and pan-cellular Interferon response reporter with the community - developed by Molofsky lab postdoc Sarah Anderson. biorxiv.org/content/10.648…

Really important tool @AnnaMolofskyLab @Molofsky_lab to study interferon response in vivo! The IFN-brite (Bright Reporter of Interferon sTimulated gene Expression) 🐁: A genetically encoded reporter reveals interferon responses in multiple cell lineages biorxiv.org/content/10.648…

Our group has discovered a new mechanism that regulates plasticity in the developing brain - led by @NTharuna and team, now online at @NatureNeuro collaboration with @christophkirst @martinucsf @dlswaney nature.com/articles/s4159…

Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling cell.com/cell/fulltext/…

amazing story from @Molofsky_lab on a cell type you've maybe never thought about but is critical to shape local immune responses after brain injury

Our newest paper studying immunosuppressive astrocyte-GBM interactions using RABID-seq is out in @Nature today! Congrats to Brian Andersen and @CamiloFaustAkl! nature.com/articles/s4158…

Between alarms and sheltering, I learned last night that my postdoc mentor, Professor Atul Butte @atulbutte, has passed away, and he is only 55 years old. This is devastating news 💔. Atul was a giant in so many ways. He was a visionary leader in translational bioinformatics @Stanford who reinvented himself as a pioneer of AI in medicine @UCSF. He published hundreds of papers, founded multiple companies, was elected to the National Academy of Medicine, and recently to the American Academy of Arts & Sciences. But Atul was much more than his achievements. He possessed something rare in science - infectious positivity. Every encounter with him, no matter how low I felt going in, I'd leave optimistic and energized to pursue my goals. After every talk he gave, students would line up to tell him how he motivated them to do something big with their lives. Another rare trait was his kindness and generosity with credit. Atul taught me: "credit is indefinitely divisible." In a field where people often take undeserved credit, this was inspiring. I will miss Atul, like so many others will. He is survived by his wife Gini and daughter Kimi, but his legacy will live on through his countless trainees and colleagues worldwide.

That's right. "Nothing short of devastating" @ScienceMagazine science.org/doi/10.1126/sc…

Among the shocking aspects of the @OfficialCCSF incident 1) leadership did not halt this antisemitic and personal attack. 2) an attendee is gleefully laughing throughout the entire tirade

These things MUST happen: @OfficialCCSF must be held to account, and TERMINATE the employment of Maria Salazar-Colon. @SEIU221 must likewise terminate Colon’s employment. Colon should be fined and make RESTITUTION to the victim of her vile racism and antisemitism. Immediately.

❤️👏🏻❤️👏🏻

The peer-reviewed version of expansion in situ genome sequencing is now out in Science! The news is bittersweet – when we first revealed this last September, I never guessed it would be my final paper in academia, but a lot has changed. A few parting thoughts:

In a new Review, scientists discuss how interactions between the nervous and immune systems could impact neurological disorders and allergy-related behaviors like food avoidance. @nick_mroz @AnnaMolofskyLab @Molofsky_lab Learn more in Science #Immunology: scim.ag/4dkHAV4

A rare but honest statement from @alzassociation about the dangerous myths being perpetuated by @RFKJr_Official about Alzheimer’s disease and our incredible research and progress. alz.org/news/2025/kenn…

There is a remarkable extent of bi-directional crosstalk between the nervous system and Type 2 immunity (vs infectious parasites, allergens, irritants, and toxins). A new and superb review @SciImmunology science.org/doi/10.1126/sc…

There are days in life that shake you. I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at @Columbia & academic career... 1/🧵

If the US claims to be punishing Columbia for allowing what it describes as “illegal protests” and failing to protect students from “anti-Semitic harassment on campus”, why is the gov mainly terminating medical, public & environmental health funding that keeps us safe? 6/