Sreya Ghosh

Check this out, excited to see the very final version of our Review on type III #interferons finally out! @dfrboehmer @ArtistInScience @kjena21 Sara Svensson Akusjärvi 👇👇👇 doi.org/10.1146/annure…

@Lo_Zanzi @harvardmed @Harvard Extremely proud and fortunate to have trained with you. Congratulations, Professor!! 🥂

More than thrilled to share that I’ve been promoted to full (tenured) Professor @harvardmed @Harvard. This only happened because of the hard work of many people, but I want to dedicate this promotion to my grandmas, Nonna Maria & Nonna Vevè. A #FirstGen thread 🧵 1/x

#MysterySolved! #BeyondInflammasome! Amazing story @MagarianBlander &co just out @Nature: human caspase-5 exists in 3 forms & CASP5c favors #gut #repair by controlling beta-catenin signaling in transit amplifying cells during intestinal damage #IBD! nature.com/articles/s4158…

#JoinUs! I’ll be presenting @ImmunologyAAI #IMMUNOLOGY2026™ on Friday 4/17: 1) a new unpublished story on how to harness #innate anti-fungal responses to potentiate #adaptive immunity 2) how #Immunometabolism determines survival of the host during microbial encounter!

Great fun to write this review on Kupffer cells with @FGinhoux and @Kubes_Lab, covering origin, diversity and roles in immunity and metabolism, now out @NatRevImmunol. Huge credit to Bruna Araujo David, @frarro1 and Camille Blériot for driving this work. rdcu.be/fckoZ

Our lab is recruiting both a postdoc and research technician to start in May/June! If you know anyone interested in investigating mechanisms of metastasis and immune suppression in cancer through developing innovative mouse models and studying senescence, please spread the word!

#WeekendRead! #RemeberMe! @snaga13 @JD_Buenrostro &co show @nature that intestinal stem cells remember multiple cycle of inflammation by epigenetically favoring AP-1 accessibility, thus increasing proliferation & repair, but also favoring tumorigenesis #citeas" target="_blank" rel="nofollow noopener">nature.com/articles/s4158…

Myeloid cells infiltrate tumors from early transformation to advanced disease; however, their plasticity complicates therapeutic targeting. Nogales-Pons et al @Casanova_Acebes review emerging technologies that uncover unexpected cellular states & functions hubs.la/Q046y-Bs0

happy to share our protocol on studying pH dependent regulation of bimolecular condensates. credit to Zhongyang, Zhe, and particularly Krish from @JRTlab for imaging analysis method. Open access. no paywall. cell.com/star-protocols…

#WeekendRead! #SmartTumor! #EveryCellIsAnImmuneCell! Amazing @Nature by @Mariapalcolea @GSkrupskelyte Rojo &co! Nascent tumors induce a #WoundHealing program in surrounding #fibroblasts driving a #PreCancerousNiche that fosters tumorigenesis! nature.com/articles/s4158…

Out today in @cellcellpress new work from the lab led by Abby Xie and @jules_stef asks, when and why do cells use the TCA cycle?

The varied personas (modifications) of NLRP3, the master inflammasome sensor - a masterful review!

Our latest review is out, a comprehensive synthesis of #tissue #Tregs. It has been a decade since @AnnualReviews #immunology last reviewed #TissueTregs, and there have been enormous advances and conceptual leaps forward in the field annualreviews.org/content/journa…

@LabWaggoner @CincyResearch Congrats, Steve! 🥂

Grateful to my peers, mentees, nominators, and the selection committee for their recognition of my commitment to mentorship at the annual @CincyResearch Faculty Awards! And to Dr Cheng for her generous presentation

📢 the Galia lab is growing and welcomes highly motivated postdocs to join a collaborative, energetic team studying mucosal immunology and immunometabolic regulation

Too much data, too little thinking. A important essay from Ruslan Medzhitov on the importance of understanding data, not just generating it. A must read. @RMedzhitov @YaleIBIO nature.com/articles/s4157…

Review @AnnualReviews @dfrboehmer @ArtistInScience Molecular, Cellular, Tissue, and Organismal Functions of Type III Interferons annualreviews.org/content/journa…

#DirtyIsBetter! @RMedzhitov, Erickson &co show @Nature that pet shop mice are protected from #allergy thanks to cross reactive type I (or tolerogenic) immune memory that prevent type II allergen-driven responses! nature.com/articles/s4158…

Happy to share our new paper @PLOSBiology on crosstalk between interferons and tissue repair. IFNs are critical for antiviral defense but excessive production is linked to delayed recovery. We found that at high concentrations, IFNs co-opt the downstream portion of the Hippo developmental signaling pathway to curtail epithelial repair and regeneration. Huge congrats to first author @krupa_subs and co-authors @YaleMed @Yale_LabMed @YaleIBIO journals.plos.org/plosbiology/ar…