Berle Lavode

@chaseharris98 I'm positive that's not why it's structured as a non-profit. Lmao. Can't believe he would even try to pretend otherwise.

Why money will become meaningless according to Sam Altman

@adalluch Some would just take that as an invitation to raw dog it on the first date.

I want an army of kids and I want them now. 😂 It scares 99.99% of men unfortunately.

@daatdarling Thank you self checkout machine for not making me talk to a human.

I’m so concerned about always being polite to people in public that my brain went into autopilot and I said “thank you” to the self checkout machine.

@saylor Build a house of cards. Wait for the right moment to rug it. Profit?

Pay with Dollars. Eat the Pizza. Keep the Bitcoin.

@BowTiedBroke 1

Okay this is a question for the men…my wife’s giving me a hard time about this. (I swear I don’t do this on purpose..it just happens somehow every once in a while) How many days in a row will you wear the same jeans without washing them? 🤷‍♂️

@BreannaMorello $20 cheeseburgers are also a problem. Even the price of a low grade fast food burger is getting out of hand.

Tip culture has become toxic. Everyone wants a 20%+ tip on top of a $20 cheese burger. If tipped workers aren’t paying income taxes, this problem will only get further out of control. Abolish federal income tax for everyone.

Why do all my replies show 31 Dec 69? Some kind of known issue?

@thegarybrecka This is true even for things that you don't normally eat that would otherwise be good for you if you did eat them regularly. Your body becomes more efficient utilizing whatever it is you put into it the more it is exposed to it (for various reasons).

Your body can’t use what it doesn’t recognize.

@Bad_AI_ @AlpacaAurelius Well...it's Japan so they pissed in the bottle instead of on the person.

@AlpacaAurelius is that a piss?

When people pass out drunk in Japan, they're gifted water In America, you'd be robbed

@IterIntellectus Has to be an epic quest, not just a fetch quest.

@tokyosunbather 🤣🤣🤣🤣🤣

@oldbooksguy Yeah...I just go to sleep when I want to go to sleep. No mental tricks, special sleeping conditions, or supplementation needed.

You, a modern biohacker: No screens after 8, melatonin gummies, eye mask Meanwhile Napoleon:

@JameelHassan_ Nice job!

my monthly expenses are less than one of my paychecks. worked vv hard to get here lol

@PsycheWizard I can sit in silence easily. The ideas don't come though. I just run up against a wall of nothing.

@SymoneBeez Easier to make money as an entrepreneur if you already have some money to start.

People finally talking about how a high paying career is better than entrepreneurship for most people

@LeadersJunction Can you force it into form by putting it out there? See my profile for GoFundMe link (joking but not joking)

Psychologist reveals why programming your subconscious can help you achieve anything‼️‼️

@AJA_Cortes There is some research dealing with aspirin and cancer treatment, but I believe that is for low dosage. Not sure why you would take such a high dose. @grok what is the current research on aspirin and cancer?

Where did this trend come from of people taking excessive amounts of aspirin? Why do people think this is a good idea?

@VitallyMelanie Yeah...I can't even do the first one. Going to have to work up to it

“I feel old at 30 what should I do?”

@bryan_johnson Bloody Mary. Bloody Mary. Bloody Mary.

Just ate broccoli while making direct eye contact with my reflection. Epigenetic age instantly dropped by 10 minutes. Recommend.

@Outdoctrination Great post

The KEY to high energy, creativity, motivation and vivid dreams, you want more DOPAMINE. Here is the FULL COMPREHENSIVE GUIDE on optimizing it with nutrition & lifestyle: NUTRIENTS FOR DOPAMINE SYNTHESIS. This is the synthesis pathway for dopamine. ➜ TYROSINE (animal protein) ➜ IRON (red meat, eggs) ➜ Vitamin C (fruits, juices) ➜ Vitamin B6 (animal protein) Are your fundamentals for raw material. Vitamin C increases dopamine output by 50-100%. Vitamin C is needed for the production of dopamine, but it also increases the rate limiting enzyme tyrosine hydroxylase, & protects dopamine producing neurons from oxidative damage. L-Tyrosine cures (some) depression. • Many cases of depression are largely dopamine deficits • These cases have low plasma tyrosine, the precursor to dopamine • Supplementing it can rapidly replete dopamine 3,200 mg/day in one study had this effect. You have two main brain centers that produce dopamine: 1. The substantia nigra 2. The ventral tegmental area These dopaminergic centers project dopamine, sending it to other parts of the brain. The prefrontal cortex, nucleus accumbens, striatum and pituitary RECIEVE dopamine. SEROTONIN inhibits dopamine, at every level. ‣ Connects to dopaminergic brain regions, slowing down production. ‣ Supplementing its precursors (tryptophan, 5HTP) lowers dopamine ‣ Dopamine gives pleasure and motivation, serotonin anhedonia and dullness What causes high serotonin? Well… Serotonin is produced in the brain during times of inescapable stress. Essentially, any situation you get put in where you feel helpless. A low tryptophan diet massively improves depression. Tryptophan is the precursor to serotonin. People with IBS often have anxiety, depression & high serotonin. Lowering tryptophan in the diet is therapeutic, as it lowers serotonin. Tyrosine gets into the brain (to make dopamine) from the blood. Its uptake into the brain is BLOCKED by other amino acids: BCAAs and tryptophan. The levels of these other amino acids will be higher after consuming them, and also during stress or insulin resistance. Another dopaminergic amino acid is PHENYLALANINE. Phenylalanine is not only a precursor to dopamine, but it also depletes brain serotonin, which should further enhance dopamine production, since serotonin itself halts dopamine output. Carbs are important for dopamine production, too. • Carb restriction frees tryptophan from its binding protein, allowing it to block tyrosine uptake in the brain • Insulin promotes dopamine release • Insulin ALSO promotes transport of tyrosine into the brain • The brain relies carbs for ENERGY Red light therapy enhances dopamine production. It can increase dopamine producing cells by ~40%. This type of light is absorbed by mitochondria, protecting dopamine producing cells from ENERGY depletion & death. Support energy, support dopamine. Creatine also improves dopamine. Once again, a component of the system that preserves ENERGY production in the brain, which allows these neurons to survive and continue to pump out dopamine. Vitamin E enhances dopamine output. Dopaminergic cells in the brain are highly susceptible to oxidative damage, but vitamin E prevents this. Controlling antioxidant status in general is VITAL for maintaining dopamine production. One HUGE contributor to oxidative stress is excess IRON. While we need iron for dopamine synthesis, it can easily become toxic if not handled properly. The iron can accumulate in the dopamine producing centers of the brain and literally rust them, damaging them. One thing that can be helpful in restoring iron balance is LACTOFERRIN. It prevents the inflammatory accumulation of iron in cells. Blood tests for: serum iron, transferrin + %, CBC, ferritin, TIBC can help ensure you don't overload. N-Acetylcysteine doubles dopamine levels. By serving as a precursor to the master antioxidant glutathione, NAC protects dopamine producing cells from death. It also acts as a neurotransmitter in its own way. The most important antioxidant supporting nutrients (for protecting the dopamine producing neurons): • Vitamin E • Vitamin C • Glycine • B1 • B2 • Zinc • Copper • Selenium • Carnosine • Iron Low dopamine can start in your GUT. Endotoxin & subsequent inflammation decimate dopamine synthesis. Endotoxin is from bacteria in the gut. People with low dopamine conditions have high endotoxin. If you have any type of gut symptom, you can bet you have high endotoxin, too. The gut is almost always the missing factor in people who have low energy & motivation, especially when they don’t respond to things that normally raise dopamine. Another KEY to high dopamine is LIGHT. Bright light throughout the day suppresses melatonin. Melatonin inhibits dopamine production at dopamine producing brain centers. Bright light therapy can improve low dopamine conditions. Bright light is also key because it regulates your circadian rhythm. Not only is dopamine, like everything else, produced on a time dependent circadian rhythm, But circadian alignment improves sleep. Sleep deprivation causes the loss of dopamine receptors in the brain. This brings us to the regulation of dopamine signaling. Your baseline (tonic) and stimulated (phasic) dopamine levels should be at the proper levels, and complement each other. This is regulated by METHYLATION (COMT) - a system we must nourish to fully capitalize on dopamine. How can we best optimize methylation for dopamine signaling? Some good starting points: Adequate: · B2 · B6 · B9 · B12 · Choline · Creatine · Glycine In the diet. A test for homocysteine can clue you in to how your methylation is doing (though it is not all encompassing).