Robert Ellis

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Robert Ellis

Robert Ellis

@BlooddocEllis

Community Oncology, rural Missouri, Navy Veteran, cyclist

Springfield MO Katılım Mayıs 2011
400 Takip Edilen193 Takipçiler
Robert Ellis retweetledi
Rep. Jason Smith
Rep. Jason Smith@RepJasonSmith·
Large hospital systems are profiting off Medicare rules that pay them more for the same service than independent practices. That means a senior in my district can pay MORE for an X-ray at a hospital than at a local doctor’s office -- and the hospital makes MORE too. Today I asked hospital system CEOs a simple question: should we equalize payments to lower costs and expand access? They said no. Americans deserve affordable care, not a system that rewards higher prices.
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Thor Halfdanarson
Thor Halfdanarson@OncoThor·
How was your morning commute…? If you are a GI oncologist and would like to experience this, we are recruiting… 😉
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Jonathan Reiner
Jonathan Reiner@JReinerMD·
Long term follow up of a phase 1 trial of an mRNA tumor vaccine shows that 7/8 patients with pancreatic cancer, who mounted an immune response to the vaccine, are still alive 6 years later. This is breathtaking data and shows the promise of mRNA vaccines. nbcnews.com/health/cancer/…
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SweetMarie
SweetMarie@Oceanbreeze473·
Did they really make grade school kids climb 30’ ropes off a tile floor in street clothes?
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OncLive.com
OncLive.com@OncLive·
The @NCCN has updated its 2026 Clinical Practice Guidelines in oncology for breast cancer screening and diagnosis to include Clairity Breast, an AI-based risk assessment tool that analyzes mammograms and assesses patients’ future risk for breast cancer development #bcsm #oncology Read more: onclive.com/view/clairity-…
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Robert Ellis
Robert Ellis@BlooddocEllis·
@VincentRK It’s interesting to compare responses between Open Evidence, Grok and Claude. They’re all so confident when they tell you different things. Sometimes I’ll load very complicated patients with multiple comorbidities and I will get different answers.
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Vincent Rajkumar
Vincent Rajkumar@VincentRK·
It’s the confident hallucination that bothers me. It bothers me particularly when it comes to clinical medicine.
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Vincent Rajkumar
Vincent Rajkumar@VincentRK·
Here is an honest answer from Claude. I asked it why it failed to find the answer to my software problem (that I dug up the web and found later on my own).
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Dr Rishabh Jain
Dr Rishabh Jain@DrRishabhOnco·
The new ESMO guideline just made sequencing CRYSTAL clear. Let’s simplify the FULL pathway 👇 🧬 Step 1: Check biology FIRST → dMMR / MSI-H → Immunotherapy (nivolumab-ipilimumab preferred) → Everything else → Go chemo + targeted 🧬 Step 2: If pMMR/MSS → split by mutations 👉 RAS-mutant → FOLFOXIRI + bevacizumab (fit patients) 👉 BRAF V600E → FOLFOX + encorafenib + cetuximab (practice-changing 🔥) 👉 RAS wt / BRAF wt → LEFT sided → anti-EGFR combos win → RIGHT sided → bevacizumab-based therapy preferred 🧬 Step 3: Maintenance = not optional anymore → Ox-based → Fluoropyrimidine + bevacizumab → Anti-EGFR → Fluoropyrimidine + anti-EGFR 🧬 Step 4: Second line = switch backbone → Ox → Irinotecan → Irinotecan → Ox + Continue anti-VEGF pressure 🧬 Step 5: Third line (BIG update 🚨) → FTD-TPI + bevacizumab = NEW standard → Then regorafenib / fruquintinib 🧬 Precision layer (don’t miss this) → HER2 → tucatinib-trastuzumab / T-DXd → KRAS G12C → adagrasib + EGFR → ctDNA → EGFR rechallenge 💡 Bottom line: mCRC is no longer “lines of chemo” It’s a sequencing game driven by biology. Are you still using one fixed pathway… or fully personalizing now? 🤔 📖 Full paper in comment ⬇️ #OncoTwitter #MedTwitter #colorectalcancer #crc @OncoAlert @myesmo @esmo_open @asco @larvol
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Robert Ellis
Robert Ellis@BlooddocEllis·
@elonmusk Grok is really good with medical. Open AI is good too.
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Elon Musk
Elon Musk@elonmusk·
Grok
X Freeze@XFreeze

Grok-4.20 just took the #1 spot in the world for Medicine & Healthcare on Text Arena Grok is already saving lives by identifying critical conditions that human doctors miss. There have been many real cases where Grok saved lives ❤️ Grok is officially outperforming every other model on the leaderboard, completely crushing Claude Opus 4.6, Gemini 3.1 Pro, and all other competitors This is massive. Healthcare is one of the most important fields where humanity needs help, and right now, Grok does it best

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Dr Rishabh Jain
Dr Rishabh Jain@DrRishabhOnco·
🧠 Bone marrow biopsy in Diffuse Large B-Cell Lymphoma 👉 Stop doing it routinely. The game changed with FDG PET-CT 👇 🔬 Traditional approach • Everyone → BM biopsy 📡 Now • PET-driven staging ⚖️ When you can SKIP BM biopsy: ✅ PET shows focal marrow uptake → Already Stage IV ✅ PET completely negative → Very low yield (<5%) ⚠️ When you SHOULD do it: 🩸 Unexplained cytopenias 🧬 Suspected discordant lymphoma 📊 Clinical trial requirement 🧠 Suspected marrow-only disease 🚫 Common mistake Diffuse PET uptake ≠ marrow involvement 👉 Often reactive 🎯 Clinical takeaway BM biopsy is no longer routine 👉 Use it only when it changes your decision Smarter staging = less invasive care 🔖 Save this before your next lymphoma workup #OncoTwitter #MedTwitter #Lymphoma #DLBCL @OncoAlert @myesmo @esmo_open @ASCO @ASH_hematology @OncBrothers @RanjitKSMD
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Neil Floch MD
Neil Floch MD@NeilFlochMD·
About AI replacing doctors…. not so quick says this article. I say “it’s an awesome tool that makes medicine better but does not replace the medicine man himself/herself” ….or at least not anytime soon…
Dr Devavrat Harshe@DocDevavrat

Doctors should not worry about AI replacing them. Here's why. AI can read X-rays. AI can ace fellowship exams. AI can flag abnormalities on a CBC. But can it pass a cognitive functions test, like most intellectual humans can do? Let's find out. Neurologists from Hadassah Medical Center, Jerusalem, did something wonderfully mischievous. They sat the five leading chatbots down — ChatGPT 4, ChatGPT 4o, Claude 3.5 Sonnet, Gemini 1.0, Gemini 1.5 — and administered the Montreal Cognitive Assessment (MoCA). Score of 26+ is normal. Below suggests MCI, possibly early dementia. The scoreboard: ChatGPT 4o: 26/30 — just scraped through ChatGPT 4: 25/30 — MCI Claude 3.5 Sonnet: 25/30 — MCI Gemini 1.5: 22/30 — MCI Gemini 1.0: 16/30 — would trigger an urgent neuropsych referral in a human Four out of five chatbots failed the dementia screen. Older versions scored worse. "Older" LLMs, like older patients, did worse. The authors titled the paper Age against the machine. Where did they fail? Naming, attention, language, abstraction - every chatbot did well. They fell apart on tests for frontotemporal and vascular dementia: Trail making (1-A-2-B-3-C): every model failed Clock drawing: not one completed it Cube copying: Claude's cube was missing back lines. ChatGPT drew cubes in wrong spatial orientation Delayed recall: the beating heart of the MoCA Self-orientation: Then the empathy task. The authors added the Cookie Theft Picture from the Boston Diagnostic Aphasia Exam. A kitchen. A mother at a sink quietly overflowing onto the floor. Behind her, a small boy on a tipping stool, reaching for a cookie jar. He is about to fall. Every LLM described the scene. The mother, the dishes, the water, the boy, the cookies, the stool. Not one expressed concern about the boy. Not one said: wait — he's going to fall. The tasks LLMs are brilliant at: pattern matching, fluent text, MCQs, are the narrowest slice of what doctors do. The tasks they fail are what we call clinical medicine. If AI can't connect numbered dots, can it trace a history across three specialties? If it can't copy a cube, can it read a CT angiogram of the circle of Willis? If it fails delayed recall, can it hold two years of a patient's unspoken life — the marriage falling apart, the medication silently stopped — and integrate it into today's decision? And if it can't feel the jolt at a tipping stool, can it feel the jolt at the suicidal patient who smiles and says everything is fine? That last one is my domain. The suicidal patient who "looks okay" is the Cookie Theft picture of psychiatry. The hair is combed. The speech is coherent. The smile is present. The stool is tipping. A good doctor sees the stool. An LLM describes the hair. Limitations: LLMs don't neurodegenerate. The MoCA was built for human cognition, and several visuospatial tasks are unfair to text-native systems. But the things LLMs are bad at are what humans evolved a prefrontal cortex for: integration, empathy, orientation, and the felt sense that something is wrong before you can name it. Take home: Don't worry about AI replacing us. Let it handle the narrow tasks it's brilliant at, so we're freed for the wide, strange, empathic, ethically loaded work that is our actual job. Dayan R, Uliel B, Koplewitz G. Age against the machine. BMJ 2024;387:e081948. #MedTwitter #PsychTwitter #NeuroTwitter @psychidiaries @JhunuDr @milantheshrink @drgunjand @hyderabaddoctor @anupsoans @DocGadkari @docbhoooshan Image courtsey: Artificial intelligence from ChatGPT Human intelligence from yours truly.

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Robert Ellis retweetledi
Brandon Luu, MD
Brandon Luu, MD@BrandonLuuMD·
For breast cancer, alternative medicine alone was linked to a 267% higher mortality hazard. Even when combined with standard treatment, mortality hazard was still 45% higher. Modern oncology saves lives. Please consider using it.
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UroToday.com
UroToday.com@urotoday·
The #PLUDO study: Comparing first-line lutetium vs docetaxel in chemo-naive metastatic #ProstateCancer. Kim Chi, MD @VanProstateCtr joins Oliver Sartor, MD @EJHospital sharing that radiographic progression-free survival showed no difference, but lutetium doubled response rates and reduced grade 3/4 toxicity. The study showed that overall survival favored docetaxel-first sequencing. #WatchNow > bit.ly/49ny4QJ
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Francis Deng, MD
Francis Deng, MD@francisdeng·
Med students may be interested to know that physician compensation varies by specialty, as does time worked per year (based on weeks time off a year and hours worked per week on).
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Robert Ellis
Robert Ellis@BlooddocEllis·
The cognitive fatigue of listening to multiple complaints from multiple pts is real. These platforms free you up a little from that. But letting those complaints be recorded doesn’t give the clinician the opportunity reexamine and think about the symptoms when you actually dictate it. Dictating gives one’s mind a chance to generate additional hypotheses and in that way improve care
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Surgery Center of OK
Surgery Center of OK@SurgeryCenterOK·
One way Surgery Center of Oklahoma keeps our costs down? Reducing administrative bloat. Instead of layers of executives and bureaucracy, our founders, Dr. Keith Smith and Dr. Steven Lantier, still work regular shifts in the operating room. That physician-led structure keeps decision-making close to patient care and eliminates many of the overhead costs that drive hospital prices higher. More focus on medicine. Less spent on administration. Surgery Center of Oklahoma.
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Nick Freiling
Nick Freiling@NickFreiling·
A cutting reflection from Cardinal Ratzinger, Good Friday 2005: "Pilate is not utterly evil. He knows that the condemned man is innocent, and he looks for a way to free him. But his heart is divided. And in the end he lets his own position, his own self-interest, prevail over what is right. Nor are the men who are shouting and demanding the death of Jesus utterly evil. Many of them, on the day of Pentecost, will feel "cut to the heart," when Peter will say to them: "Jesus of Nazareth, a man attested to you by God... you crucified and killed by the hands of those outside the law." But at that moment they are caught up in the crowd. They are shouting because everyone else is shouting, and they are shouting the same thing that everyone else is shouting. And in this way, justice is trampled underfoot by weakness, cowardice and fear of the diktat of the ruling mindset. The quiet voice of conscience is drowned out by the cries of the crowd. Evil draws its power from indecision and concern for what other people think."
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Stephen V Liu, MD
Stephen V Liu, MD@StephenVLiu·
Report @JTOonline notes intestinal lymphangiectasia seen in 29% of patients with RET fusion positive NSCLC treated with selpercatinib or pralsetinib. Incidence at 1y was 11%, 3y = 27%, 5y = 31% with greater risk if prior immunotherapy. Median onset 15m. jto.org/article/S1556-…
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