Sam Landry

866 posts

Sam Landry

Sam Landry

@BreakingBiochem

Biochemistry of immunology, protein structure and protein folding. Flipping the classroom into the digital world for Tulane students and everyone else.

Tulane University Katılım Nisan 2013
57 Takip Edilen357 Takipçiler
Sam Landry
Sam Landry@BreakingBiochem·
@PDevaux_FD Assuming your original single-volume edition disintegrated.
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Pierre Devaux
Pierre Devaux@PDevaux_FD·
Who remember these manuals which have been useful for so long in the daily work of the lab? We call them the ‘MANIATIS’ the name of one of the co-authors. Although why not the name of one of the other co-authors?
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Jay K. Kolls
Jay K. Kolls@GotTcells·
Based on pioneering work by @BAGarvy and Fran Lund that B cells are key antigen presenting cells for Pneumocystis (a common fungal pneumonia in infants), @MNoell_12 figured infants must have anti-fungal IgMs that predict T cell responses. They do! insight.jci.org/articles/view/…
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Eric Topol
Eric Topol@EricTopol·
This is why 2nd boosters should be available for all health care workers now. A report on ~30,000 Israeli HCWs indicates 65% lower risk of breakthrough infections during the Omicron wave (4 vs 3 doses) @JAMANetworkOpen jamanetwork.com/journals/jaman…
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Eric Topol
Eric Topol@EricTopol·
Just published @NEJM During Omicron, the 2-shot mRNA vaccine effectiveness among >250,000 children age 5 to 11 years old: vs hospitalizations was very high—83% vs PCR confirmed infections 65% nejm.org/doi/full/10.10…
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Science Magazine
Science Magazine@ScienceMagazine·
Although the handshake and other types of physical contact are gradually returning, they have been on hiatus due to #COVID19. Such changes have already altered the epidemiology of a range of infectious diseases. Learn more in a new #SciencePerspective: fcld.ly/al7glzl
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Eric Topol
Eric Topol@EricTopol·
What is immune imprinting and why it is important? A superb explainer “Our first encounter with the spike antigen, either through infection or vaccination, shapes our subsequent pattern of immunity through immune imprinting" —@BoytonRosemary ft.com/content/4f71ac…
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Sam Landry
Sam Landry@BreakingBiochem·
Second paper showing unfavorable imprinting by omicron, likely meditated by antigen processing...Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure science.org/doi/10.1126/sc…
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Sam Landry
Sam Landry@BreakingBiochem·
T cells could account for slower loss of vaccine protection against severe disease.
Nature Portfolio@NaturePortfolio

A @NatureMedicine paper presents a model that predicts the effectiveness of COVID-19 vaccines against circulating SARS-CoV-2 variants, which could help guide more rapid public health and research responses to new variants of concern. go.nature.com/3O5b8Za

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Sam Landry
Sam Landry@BreakingBiochem·
On Jan 5 the State would have actually had 400,000 cases and reported (accurately?) 1412 hospitalizations (0.35% of cases). All this to say that the current infection rate is probably 194/0.0035=55,000. That's 52 times higher than reported. I'm not going out again for a while.
Sam Landry@BreakingBiochem

COVID infections are grossly under-reported. On May 31st, the 7-day average was reportedly 1,064, and hospitalizations were at 194, or 18%. Of course, we know that 18% of COVID+ people are not going to hospitals.

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Sam Landry
Sam Landry@BreakingBiochem·
COVID infections are grossly under-reported. On May 31st, the 7-day average was reportedly 1,064, and hospitalizations were at 194, or 18%. Of course, we know that 18% of COVID+ people are not going to hospitals.
Sam Landry tweet media
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Sam Landry
Sam Landry@BreakingBiochem·
Jan 5 the State would have actually had 400,000 cases, and reported (accurately?) 1412 hospitalizations (0.35% of cases). All this to say that the current infection rate is probably 194/0.0035=55,000. That's 52 times higher than reported. I'm not going out again for a while.
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Sam Landry
Sam Landry@BreakingBiochem·
As we approached the peak of Omicron (Jan 5), 12,757 cases were reported, but the number was likely higher than 10% of the population. Tulane was testing like crazy and getting 12.5 % positive.
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