Caroline Diorio

Newly minted PhD

In an interesting interview from #CART26, @EvanWeberPhD (@PennMedicine @ChildrensPhila) discusses the current understanding of core regulators of #CARTCell persistence and outlines his research in this area.🩸 Click here to find out more: 🎥 ➡️ ow.ly/IcTA50YoAk9 #ImmunoOnc #CARTCell #HemOnc

In this Q&A on Nucleus, author Kevin McNerney, MD, shares background on how his research came about, findings that particularly surprised him, and how these findings are guiding current and future initiatives. Read more on Nucleus: ow.ly/MF9m50Ypq0F

Excited to share our new paper in @NatureMedicine uncovering the role of CD4⁺ CAR T cells in CirAEs after BCMA CAR T therapy. @MatthewHoMD @paruzzol @jh_noll @JoeFraietta @MarcoRuella @CohenAd_MMdoc @PennMedicine @PennCancer nature.com/articles/s4159…

So proud of my mentee @JGrenierMDPhD on his fantastic talk at #ASH25 on CD19 CAR T cell and microenvironment biology in patient bone marrow. Congrats Jeremy!

Happy to announce publication of our new paper: CCR5-targeted allogeneic gamma–delta CD19 chimeric antigen receptor T cells for HIV-associated B cell-malignancy immunotherapy | Nature Biomedical Engineering Congratulations, Angel and Team!!! nature.com/articles/s4155…

A new CHOP study finds that combining a specialized diet with an approved medication interrupts the growth of high-risk neuroblastoma by reprogramming tumor behavior. Learn more at: ms.spr.ly/6015sSuDW. @Nature

Durable CAR T persistence is among the great unsolved challenges within our field. But what do we actually mean when we say a CAR T cell is "persistent"? @JGrenierMDPhD, @EvanWeberPhD and I attempt to answer this question in our new review @trendscancer. 1/

In an exciting collaboration with the #ImmuneHealth lab at Penn @benfens investigated the developing immune system of preterm infants. Even pre-term infants make surprisingly robust CD8 T cell responses to diverse infections. medrxiv.org/content/10.110…

So grateful for this generous support for our work from @chadtough and @laceemupforlibby!

"Modeling the HLH immune synapse uncovers critical roles for IS termination, cytokine intensity, and target cell death" #HLH travels under many names (#MAS, #CRS, ...), all united by T-cell hyperactivation. doi.org/10.1182/blood.…

Next-generation IL18-armored CAR T cell therapy shows promise for patients whose lymphoma resisted multiple other cancer treatments, including commercial CAR T cell therapies. @carlhjune @NEJM spr.ly/6016NzZJ6

Treating the untreatable - "Enhanced CAR T-Cell Therapy for Lymphoma after Previous Failure" @PennMedicine @nejm #immunotherapy nejm.org/doi/full/10.10…

Introducing, the Canada Strong Pass.

Great turnout in Philly for #StandUpForScience2025 #NIH

@EvanWeberPhD @kpmueller1 @CancerResearch Congratulations @kpmueller1 and @EvanWeberPhD on this well-deserved fellowship! Great talent and amazing mentorship 🤩🎉

Congratulations to Eugene Khandros (@ChildrensPhila/ @PennMedicine) on being named a 2025 @the_asci Young Physician-Scientist Awardee! tinyurl.com/4472xuht Learn more about Dr. Khandros & his work here➡️ tinyurl.com/3x7bxehm @CHOP_Research

Couldn’t be more thrilled to announce the start of my independent research group ‘Precision Immunotherapy’ starting next week in the Department of Hematology and Oncology at the University Hospital of the @LMU_Muenchen 🚀🚀 #newpi #prouddrylab #clinicianscientist #bzkf #lmu

“The impact of the collective executive orders and directives appears devastating.” scim.ag/4h5ngYC