Pierre Caron

🪐 Il a fallu 9 ans et 4,8 milliards de kilomètres pour obtenir ces images. Ce sont les montagnes glacées de Pluton 🤯

The full program for the 18th EDRA webinar (Dec 16th, 4:00 pm CET) is now available! We are excited to share the details of this final session of the year, featuring talks on RNA damage in chemotherapy, BER–MMR crosstalk, and mitochondrial DNA repair. lnkd.in/en7HV9wK

New online! Kinetic control of mammalian transcription elongation bit.ly/4ipj2wp

Online Now: Circadian PERIOD proteins regulate TC-DSB repair through anchoring to the nuclear envelope dlvr.it/TPN3ff

Our newly developed ChIP-CryoEM technique has, for the first time, visualized the moment when the UV-DDB protein recognizes and repairs UV-induced DNA damage within cells. nature.com/articles/s4146… #cryo #structure #biology

Nature research paper: Evidence for improved DNA repair in long-lived bowhead whale go.nature.com/3Lzg1NH

Online Now: Cryo-EM reveals open and closed Asgard chromatin assemblies dlvr.it/TNwxln

@SusanKilgas @ChowdhuryLab Congratulations Susan and to the lab!!👏🏼

Excited to share our new paper from Sara J. Buhrlage lab & @ChowdhuryLab! We designed CAS-010, a selective, low nanomolar USP28 inhibitor that reduces p53 transcriptional activity, mimics p53 pathway loss & disrupts 53BP1-USP28 binding, offering new insights into USP28 function.

Our lab’s insights on a recently published Science study that highlights ASB7 as a cell-cycle-regulated ubiquitin adaptor that restrains heterochromatin spread by targeting SUV39H1 for degradation. Check out our views & more of this exciting work 👉: nature.com/articles/s4139…

🎉🎉 Elated to share that my Ph.D work is now published, showing Xist upstream elements are important for Xist and autosomal gene expression. Very thankful to my Ph.D supervisor @srimontagayen, to @DimpleNotani, to @Hemantcnaik666 & the entire team for their contributions!

For all DNA repair and mutagenesis enthusiasts: the 7th edition of Fundamental Aspects of DNA Repair and Mutagenesis (VII FARM-DNA) is coming!🧬🛠 Registrations are open until July 31! To register and submit your abstract, visit: farmdna2025.com.br See you there! 😉

Join us for the next EDRA webinar. Jessica Downs will discuss on SWI/SNF at G-quadruplexes, Yasmina Djeghmoum on transcription as a regulator of HR, and Sree Rama Chaitanya on BRCA2 variants and their effects on chromatin and transcription. Don’t miss it! dnarep.sciencesconf.org/resource/page/…

First preLights post from Jenny Singh (@jennysingh91) She covers work showing that Lamin A/C maintains replication fork integrity during mild replication stress by modulating chromatin structure and restraining RECQ1 activity. #preprint #preLight ⬇️👀 prelights.biologists.com/highlights/nuc…

#IBSevents: Séminaire Grand Public le 24/06 à 10h30 par Juan Carlos Fontecilla-Camps, intitulé "L’histoire évolutive de nos cellules, obéissance ou collaboration ?": urls.fr/Jnov8U

Many thanks to the 2025 Organizing Committee who made this scientific day a success! The event ended with a potluck diner and musical entertainment provided by a group of IBS students. Here is a photo story of this annual event!

#Thread: The flash/poster Prize was awarded to Maria Val Pevida (M&P group @IBS_Grenoble) who is seeking to decipher the molecular mechanism of activation of NADPH oxidase complex NOX1 by cryogenic electron microscopy.

Last week, I presented the last results of my PhD at the main conference of Computational Biology in Brazil, X-meeting!!! 💻🧬 We have analyzed comparatively DNA repair genes from Antarctic samples coming from both surface and deep-sea sediments! Next step: finish the PhD! 🤪

Françoise Dantzer (@dantzerlab), Marco Barazas, and Marianna Genta will be speaking on June 24th 🧪! Would you like to learn more about PARP3, DSB-induced mutational signatures, or the NER mechanism? Don't miss this event! 🔬 #DNArepair dnarep.sciencesconf.org/resource/page/…

If you are interested in pursuing a postdoc combining proteomics a genomics with functional molecular biology to study ubiquitin (-like) signaling in genome biology we are looking for candidates for the next MSCA Fellowships call!!!!