Nir Ben Chetrit

Big Nature paper this week on improved lifespan (in mice!) using an antibody to block IL11 Old mice without IL11 even look healthier 🧵

NEW @preprintclub Journal Club from Anthony Altieri & Matthew Buechler @ImmunologyUofT discussing @biorxivpreprint by @ChetritNir @landau_lab @Johanna_A_Joyce that investigates the mechanisms regulating macrophage heterogeneity in breast cancer rdcu.be/dJcHB

@ktsanov @LoweLabMSKCC @MSKCancerCenter Congrats Kal!

Truly honored by this recognition, which is really a reflection of the phenomenal mentorship, environment & colleagues, incl. key collaborators @LoweLabMSKCC @MSKCancerCenter. Thank you! 🙏

@BrownLab_KUMC @AACR Hey Kristy! Let’s catch up. I’m presenting our work on the 9th eppro01.ativ.me/appinfo.php?pa… #AACR24

Time to get on a plane for #AACR24!! Can’t wait to hear about all the advances in cancer research and catch up with friends and colleagues

🔬Ready to delve deep into the #TumorMicroenvironment @AACR? Join @LabMcgaha and me as we co-chair the symposium “The Microenvironment: Beyond Surrounding the Tumor.” Featuring talks by @ChetritNir @danielzabransky @neilqtay @GauriMirji Jun Li, Ruiyuan Xu, & Xiaoyu Yuan #AACR24

@DuctalvsAcinar @AACR @LabMcgaha @danielzabransky @neilqtay @GauriMirji Looking forward!

Very excited to share our work with @MattRijn @johnhickey22 @GuolanLu @luca_bogdan @GarryPNolan @BrubakerSky @kidzik Rob West @Stanford spatially dissecting macrophage niches in human breast and colon benign and tumor tissue. biorxiv.org/content/10.110…

@ktsanov Congrats Kal!!

Excited to share our latest preprint! Here, we asked: Does a tumor’s dependence on driver mutations change after it spreads to other organs? This led us to uncover a critical interplay b/w tumor #Genetics, #Epigenetics and #AnatomicLocation... 🧵 1/n biorxiv.org/content/10.110…

Very excited to share our new paper on how mutations in SWI/SNF chromatin remodeling complexes alter chromatin dynamics and immune cell-fate to drive lymphoma, online now in @Cancer_Cell. authors.elsevier.com/c/1ijJ05TA51hO… More details in the thread below.👇 🧵 1/n

Our end-to-end workflow for 3D pathology is now published in @NatureProtocols! This includes all the steps to go from archived pathology tissues to 3D H&E-like datasets, with an emphasis on quality control for large studies. Full text at: rdcu.be/dwIYW

We’re excited to share our preprint on spatial organization in glioblastoma: doi.org/10.1101/2023.0…. We combine spatial transcriptomics (Visium) and proteomics (CODEX) to reveal a five-layer organization of cellular states and highlight a role of hypoxia as tissue organizer. 1/

@NCIDanMcVicar @landau_lab Thanks Daniel! We will check it out. Feel free to reach out and discuss the oTME details.

Very excited to share our latest work from the @landau_lab, where we uncover the spatial determinants underlying macrophage heterogeneity and self-renewal in breast cancer. biorxiv.org/content/10.110…

@IKeklikoglou @landau_lab Thanks Ioanna!

@ChetritNir @landau_lab Congrats Nir!!👏👏

@DanielaQuail @stevexniu @landau_lab @Joycelab @BrownLab_KUMC @Neil_Iyengar @LoweLabMSKCC @LabSagi Many thanks Daniela!

Fantastic team science with @stevexniu, Jesus Sotelo, and many more members of the @landau_lab, @Joycelab, @BrownLab_KUMC, @Neil_Iyengar , Dilip Giri, @LoweLabMSKCC , John Healey, Frederic Geissmann, and @LabSagi

pls check @TylerEMiller and @BradEBernstein, who have posted an exciting story on transcriptional programs of myeloid cells in glioma, similarly linking myeloid cell plasticity and TME niches as drivers of immunomodulation biorxiv.org/content/10.110…