David Johnson

@BowTiedPeptide @jpthe19th A lot of the SS-31 trials used 40mg/day dosing, would you expect a linear dose response all the way between 4-40mg for kidney health? Or in other words, how much of published benefits are being realized at a dose of 4mg?

@jpthe19th Yes. SS-31 2-4mg day for three wks before running MOTS-c 1mg a day for 10-16wks. I'll either run the SS-31 the whole time alongside or drop it halfway due to pin fatigue.

No. SS-31 before MOTS-c. SS-31 repair dysfunctional inner cell mitochondria membranes like mechanics fix engines. MOTS-c ramps up mitochondrial biogenesis. It's like an accelerator. Lead foot the gas of a POS car & watch it fall apart on the track. Cellular damage or death.☠️ SS-31 is your pit crew tuning the engine, suspension, tire pressure, etc so when you do step on the metabolic/mitochondrial gas with MOTS-c you're getting the most out of it & also mitigating potential damage.🏁

@0xexpt @PGC1a_RB @Zedzies Wouldn’t trying to reverse thymic involution be analogous to using enclomiphene to reverse low T? Ie, might a better solution not be replacing natural thymic output with TA1 and others to mimic natural function, similar to TRT for hypogonadism as opposed to enclomiphene

@PGC1a_RB @Zedzies it's fine because we will have [redacted], [redacted] and [redacted] to stop involution but also reverse it Choosing between vitality, vrill and longevity won't be necessary soon

Early TRT leads to accelerated thymic involution and reduced longevity. Not a good idea to start this stuff at too young of an age. Guys doing T in their 20's are in for a rude awakening.

@jon_charb If usdc is the L1 gas token, blacklisting an address will freeze EVERY asset on that L1 address, not just usdc

Do people like this just actually not realize that Jeremy can nuke your USDC in one click no matter where you hold them

@BowTiedYukon bumble

Yukon’s Peptide Handbook In case you missed it All of the most popular peptides BPC-157, GHK-Cu, HCG, KPV, Melanotan, TB-500, Glow, Semaglutide, Retatrutide, Tirzepatide, Carillintide and a lot more Everything you want to know Comment Bumble and I will DM it to you

You're a 19 year old kid. You are critically wounded and dying in the jungle somewhere in the Central Highlands of Viet Nam . Its November 14, 1965 . LZ (landing zone) X-ray. Your unit is outnumbered 8-1 and the enemy fire is so intense from 100 yards away, that your CO (commanding officer) has ordered the MedEvac helicopters to stop coming in. You're lying there, listening to the enemy machine guns and you know you're not getting out. Your family is half way around the world, 12,000 miles away, and you'll never see them again. As the world starts to fade in and out, you know this is the day. Then - over the machine gun noise - you faintly hear that sound of a helicopter. You look up to see a Huey coming in. But.. It doesn't seem real because no MedEvac markings are on it. Captain Ed Freeman is coming in for you. He's not MedEvac so it's not his job, but he heard the radio call and decided he's flying his Huey down into the machine gun fire anyway. Even after the MedEvacs were ordered not to come. He's coming anyway. And he drops it in and sits there in the machine gun fire, as they load 3 of you at a time on board. Then he flies you up and out through the gunfire to the doctors and nurses and safety. And, he kept coming back!! 13 more times!! Until all the wounded were out. No one knew until the mission was over that the Captain had been hit 4 times in the legs and left arm. He took 29 of you and your buddies out that day. Some would not have made it without the Captain and his Huey. Medal of Honor Recipient, Captain Ed Freeman, United States Army, died at the age of 81, in Boise, Idaho. God bless our vets!

@1984_is_today Any European country that refuses to codify free speech similar to the US should be expelled from NATO, have funding cut to zero, and tariffed into bankruptcy

@simonmaechling @IfindRetards

As a chemist: Calling mRNA a “silent killer” shows your deep misunderstanding of how biology works. Your own cells make mRNA every day. It’s how your body functions. The mRNA in vaccines is temporary, targeted, and safe. It’s a tool. Not a toxin.

@0xasrequired @0xlykt What mean?

@0xlykt a lending market that liquidates collateral on an orderbook is not priced in

Some general thoughts on farming the HyperEVM Generally, you want your farming to be highly capital efficient. The best example of this is looping stHYPE/HYPE or HYPE/HYPE on Hyperlend or HypurrFi. You may only deposit 50 HYPE but if you keep looping (at 75% max LTV for Hyperlend and 90% for HypurrFi) you can drastically increase your exposure to hundreds of HYPE deposited + borrowed at almost zero liquidation risk (unless stHYPE depegs significantly) I know a lot of people liked to LP in Hyperswap and Kittenswap but I think anyone who wasn't early will be quite disappointed by the airdrop. Most people should think of LPing as a trade which you execute when you believe the price of a pair will mean revert to the price you initialised the pool at. At 20+ million TVL you should not have been LPing for the points Unit is probably the most slept on airdrop due to there being no confirmation of an airdrop + no points program. I think Unit is the project with the biggest potential moat - especially with HIP-3, I can see Unit playing a key role in bringing tokenised equities to Hyperliquid, and this could drive huge amounts of revenue to the $UNIT token. I think TWAB of Unit assets on HyperCore/HyperEVM + bridge volume will probably be among the main criteria for a $UNIT airdrop, and I'm positioned accordingly. If you LP unit assets I think you'll get a much bigger airdrop from Unit than Hyperswap/Kittenswap - using the wrong formula to get the right answer In general, when you farm it's important to consider a realistic potential valuation of a project. My key thesis behind farming the HyperEVM is that many people do not understand the potential DeFi applications of HyperEVM<>HyperCore composability and how it is a vastly superior system compared to DeFi on Ethereum or Solana, which make up the majority of DeFi today. Certain projects are more well-positioned to take advantage of this, such as lending markets which can now offer more features - using perps as collateral, lower liquidation penalties, tokenising vaults such as HLP on HyperCore, etc. I believe lending markets such as Felix and Hyperlend will easily reach multiple billion dollars in TVL, which would justify much higher valuations than currently anticipated.

@HansAmato Using a krill oil rich in astaxanthin definitely eliminates many common probs with omega 3s

Throw your fish oils in the toilet. They’re outdated, overhyped, and oxidized garbage. Here are 2 superior alternatives: – Coconut oil – C15:0 (pentadecanoic acid) Let me explain why. 🧵

🚨 BRYAN JOHNSON: “I regret getting vaccinated for COVID. I want to trust the systems that produce science. Their role is to not sway my opinion, their role is to give me data. And they didn’t. They swayed my opinion. And that is an improper use of power.”

YES BRUV The Britain Restoring Underlying Values party will restore the once Great Britain. As leader I am held fully accountable. If the plan has not been actioned within 45 days of power I will step down from leadership. No delays. Charter below. Join the movement: Votebruv.co.uk

@gfodor Man, imagine how valuable that sensor data Lockheed got is

This is probably the video Gaetz saw. If they release it, it's over.

@gfodor experiential capital

Would be good to start thinking about the most prominent scarcities there are in a world where everyone has effectively the same amount of financial capital. If you gather the top 5 accurately you’ll be able to predict future class stratification.

@babylonlabs_io Lesgoh

the countdown begins

Idea if Trump wins in 2024: All NATO members must enact a written constitution with an exact copy of the US First Amendment. Any who fail to do so will be expelled from NATO and will lose US military protection. If NATO itself objects, the US leaves NATO and starts its own military treaty org. American defence money should not be spent defending the same tyrants that America rejected in 1776 cc: @JDVance

@nearcyan Goes great in coffee with a little theanine and taurine

the strong improvement glycine causes on sleep for most, paired with that almost everyone is technically deficient in it, paired with its half life, paired with its primarily carnivorous source, makes me wonder if we in fact were intended to eat before bed, but just not carbs

HHS Secretary Becerra just issued a PREP Act declaration for bird flu. This allows the FDA Commissioner to issue EUAs for bird flu vaccines, with no liability. The US government has ordered 4.8 million doses of bird flu from the CSL Sequirus company, produced in dog kidney cells and using a dangerous squalene-containing adjuvant. The AMA issued CPT codes for this vaccine last Friday, so doctors could be reimbursed for administering it. There have been a total of 11 cases of bird flu in the US since 2022, all mild, most involving just conjunctivitis. None were shown to have been transmitted human-to-human. Why would you need this vaccine, unless you expected a much more virulent virus to appear which had mysteriously gained the ability to spread between humans? Will there be another lab-derived pandemic? Not on my watch! #Kennedy24

@richgel999 Seems like every so often they like to remind folks they’re around…

Jessup, in The Case for the UFO: "They didn't have to come all those millions of miles from anywhere. They've been here for thousands of years. Whether we belong to them by possession, like cattle, or whether we belong to each other by common origin and association is an interesting problem, and one which may soon be settled if we keep our heads."

Every time.

@WIRED Wired is trash

A Brazilian court has announced that it will be opening an investigation into X owner Elon Musk for obstruction of justice after Musk reactivated far-right accounts that the Brazilian government had flagged for removal. 🔗 wired.trib.al/zDs9QcZ // 📷 Beata Zawrzel; Getty