Raffaella Di Micco

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Raffaella Di Micco

Raffaella Di Micco

@DiMiccoLab

Group Leader at SR-Tiget @Telethonitalia @SanraffaeleMI. Intrigued by #DNAdamage, #senescence and #stemcell biology. @ERC_research @NYSCF Robertson Investigator

Milan, Lombardy Katılım Kasım 2011
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Raffaella Di Micco
Raffaella Di Micco@DiMiccoLab·
🧨💥Our latest work is out @cellreportsmedicine! We uncovered #p38MAPK mediated #proliferation stress as the culprit of functional #impairment of #HSC during exvivo #gene #editing. p38 inhibition endows edited HSC with high #clonal #output and better preserved genome #integrity!
Lucrezia della Volpe@dellaVolpe_L

1/4- 📢I am thrilled to announce that @DiMiccoLab's latest study, "A p38 MAPK-ROS axis fuels proliferation stress and DNA damage during CRISPR/Cas9 gene editing in Hematopoietic Stem and Progenitor Cells" (cell.com/cell-reports-m…) is now out in @CellRepMed! Read more below👇

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GIIN
GIIN@GenomeIINetwork·
We thank @martakova and @MateMaus for sharing their research with our community at yesterday's seminar! Our next seminar on Tuesday, May 6th will feature Anna Kajaste-Rudnitski and Raphael Ceccaldi. Subscribe here to receive the reminder: forms.gle/HfTaFCyFicCFYN…
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International Cell Senescence Association
International Cell Senescence Association@ICSA_senescence·
1/2 We are very excited to announce the 10th Annual ICSA Meeting, which will take places in Rome, Italy on Sept 17th-19th, 2025. Registration is now open! Visit our website for details: icsa2025rome.com We look forward to seeing you in Rome!
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Alejo Rodriguez-Fraticelli, PhD
Alejo Rodriguez-Fraticelli, PhD@AlejoFraticelli·
🔥New Fraticelli lab publication🔥 “Pre-existing stem cell heterogeneity dictates clonal responses to the acquisition of leukemia driver mutations” Two new figures compared to the pre-print, with more in vivo and sequential mutagenesis data. sciencedirect.com/science/articl…
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Jacob Corn
Jacob Corn@jcornlab·
Cells are filled with toxic stuff that damages healthy proteins. Is that garbage just left to rot on the curb? No way! Ubiquitin ligases have evolved to recognize chemical damage and clean it up! nature.com/articles/s4158…
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GIIN
GIIN@GenomeIINetwork·
Our next GiiN webinar will feature Lumír Krejčí from @muni_cz and Giulia Bastianello from @IFOMresearch. Join us on Tuesday, February 4th from 5-6 PM Rome Time for a lively discussion on genome integrity maintenance here: uniroma1.zoom.us/j/95149984403
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Julien Cherfils
Julien Cherfils@CherfilsJulien·
1/7 Excited to share our team’s first paper revealing how senescent cells use the GD3 ganglioside as a Senescence Immune Checkpoints (SICs) to bypass immune surveillance published in @NatureAging ! rdcu.be/d4XXJ
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Maria Ermolaeva
Maria Ermolaeva@MariaErmolaev13·
Study shows that senescent cells literally sugar-coat themselves to avoid recognition and clearance by the immune system. nature.com/articles/s4358…
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Ana O'Loghlen
Ana O'Loghlen@TheOLoghlenLAB·
If you are interested in senescence, ageing and age-related diseases, you can apply for Postdoc and PhD Fellowships in my lab. I´ll help you with the application! Calls close end Jan 2025! Happy holidays!!!
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Andrea Ventura
Andrea Ventura@aventura71·
1/ 🚨New paper on ecDNAs from our lab! We reveal a strategy to engineer extrachromosomal DNA (ecDNA) amplifications in cells & mice. Let's dive in! 🧵👇 nature.com/articles/s4158…
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GIIN
GIIN@GenomeIINetwork·
We are deeply thankful to all the speakers for sharing their amazing finding with the GIIN community. We also thank a lot our community for attending and stimulating fruitful discussions! We wish you all a wonderful festive season. See you all in January!
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Stephanie Xie
Stephanie Xie@stephxie·
#ASH24 like no other in #ASHaiku, Come and join us 👉 🦋 inspired This is the big time, Scientific committee, Three ASH abstracts. Slay!!! Anticipating amazing 501 talks. Moderating too! Saturday oral, New human HSC state. I’m one proud mentor. 1/
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Jordi Surrallés
Jordi Surrallés@JSurralles·
Felicidades @BioInn_CIEMAT y @fibhnjs @JuanBueren @PauFerrol, @SuNAlakira @jsevilladoc @DelacalDe @josunezubicaray por este superpaper en @TheLancet y un gusto todos estos años de colaboración y amistad.
CIEMAT@CIEMAT_OPI

🧬Un ensayo clínico español ha demostrado por primera vez que la #terapia #génica es eficaz y segura en pacientes con #anemia de #Fanconi. 🔬Los resultados de esta #investigación, fruto de más de 20 años de trabajo, acaban de ser publicados en The Lancet, una de las revistas médicas de mayor impacto. Te contamos este hito internacional aquí: ciemat.es/portal.do?IDM=…

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Nature Biotechnology
Nature Biotechnology@NatureBiotech·
Genome editing with the HDR-enhancing DNA-PKcs inhibitor AZD7648 causes large-scale genomic alterations go.nature.com/3D2e4Fh
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GIIN
GIIN@GenomeIINetwork·
The last GiiN seminar of 2024 is coming soon and you don't want to miss it!! 🗣️Speakers: Ivan Marrazzi and @DiMiccoLab 🗓️When: next Tuesday (Dec 3rd), 5pm Rome - 11am NYC 📍Where: Zoom uniroma1.zoom.us/j/95149984403
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Iliev Lab
Iliev Lab@IlievLab·
Thrilled to share the results of our 8-year-long expedition into the Wild, the city of #NYC , the wild west of #LosAngelesCA , and more—in search of the roots of gut fungal commensalism! 🧵nature.com/articles/s4158…
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Keşfet

@martakova @MateMaus @AlejoFraticelli @jcornlab @muni_cz @IFOMresearch @EACRnews @TheMarkFdn