DiscoStew

The (ab)use of food frequency questionnaire data in substitution modelling - nature.com/articles/s4143… "The majority of substitution modelling analyses that relied on FFQ data had not adequately addressed fundamental limitations in measurement accuracy."

Fat Might Be Fabulous: Challenging Conventional Wisdom on American Health Law & Policy - publications.lawschool.cornell.edu/jlpp/wp-conten… "As it turns out, the vilification of saturated fat, and particularly its connection to heart disease, has never been confirmed in a careful, scientific way."

Saturated fat and cardiovascular disease prevention "a reduction in saturated fats cannot be recommended at present to prevent cardiovascular diseases and mortality."

It’s long overdue for the Dietary Guidelines to include a low-carbohydrate option for the vast majority of Americans with diet-related diseases. We are not asking for all Americans to follow this approach. It just needs to be an option. The scientific evidence is strong. As the MAHA Commission report (part 1) itself stated: “Some of the most compelling dietary intervention data comes from randomized controlled trials (RCTs) of reduced-carbohydrate diets in adults and children to reverse obesity, type 2 diabetes, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), and risk factors for heart disease such as hypertension….[R]educed-carbohydrate diets have been studied in several two-year trials, including one with five-year follow-up data. (p. 28)” Help us fix this policy gap. Download and share the media kit at lowcarbmaha.org.

"Whole-fat dairy was inversely associated with future presence of CAC. These results contradict dietary guidelines that emphasize low-fat dairy intake for the prevention of coronary heart disease."

When a bunch of anti-meat zealots wanted to create a wall of shame (btw, who paid for this seemingly expensive report?), all they got was a hall of fame... Meet "la Résistance" & join us; let's expand this list: @SBakerMD, @bigfatsurprise, @KenDBerryMD, @fleroy1974, @JoannaBlythman, @GHGGuru, @Mangan150, @GeorgiaEdeMD, @FructoseNo, @CarnivoreKeto, @hormonedietdoc, @DiscoStew66, @LouiseStephen9, @GrassBased, @Lone_Star_Keto, @FatEmperor, @zoeharcombe, @ProfTimNoakes, @SustainableDish

Is LDL a valid surrogate marker? New post 👇 buymeacoffee.com/dietarydiary/l…

"It is very likely that the effort to find a causal link between saturated fat and CVDs will be futile." "Current nutritional strategies should be seriously reconsidered and recommended protein intakes for children must be urgently reevaluated." Nice paper 👍

The apoB scam continues. New post 👇 buymeacoffee.com/dietarydiary/a…

"Our results indicate that higher levels of TC, LDL-C, and non-HDL-C are associated with a reduced risk of COPD." tandfonline.com/doi/full/10.21…

"Concurrent elevation of both LDL-cholesterol and hsCRP conferred the highest risk . . . In contrast, an isolated rise in cholesterol in the presence of low-grade inflammation (hsCRP < 2 mg/L) did not significantly raise risk." 🤔 imperial.ac.uk/news/267053/in…

The new Dietary Guidelines will drop the caps on saturated fat!! That's what FDA Commissioner @DrMakaryFDA implied yesterday 👏👏👏👏 (My head is spinning--he's citing research directly from my book!) youtube.com/watch?v=qym5dA… "Since Ancel Keys in the 1960s decided to demonize saturated fats with a hypothesis that was supported with data that was incomplete and methodologically flawed in his Seven Countries Study The medical establishment started with a robust debate...in the NEJM and the National Academy, but that debate ended in the 1970s. Because there was groupthink. The medical establishment locked arms and walked off a cliff together, deciding the reason for heart disease was that people were eating skim milk and no-fat and low-fat foods. IGNORING the role of refined carbs and so many other things that drive general body inflammation which is the precursor of fat deposition in the arteries That dogma still lives large and you see it in the food guidelines that we are revising. We are going to ensure that the guidelines are based on science and not medical dogma." Hard to believe...I've been working on this issue for 20 years. We are poised for a historic change.

Travelling through Greece. Still waiting for the plant- based Mediterranean diet to show up. Goat, lamb, chicken routinely featured in Tavernas. #plantcon

No differences in all-cause mortality or cardiovascular events in RCTs of saturated fat restriction. "a reduction in saturated fats cannot be recommended at present to prevent cardiovascular diseases and mortality"

Now peer-reviewed. As expected, there is no high-quality evidence that reducing saturated fat is beneficial. "The findings indicate that a reduction in saturated fats cannot be recommended at present to prevent cardiovascular diseases and mortality." pmc.ncbi.nlm.nih.gov/articles/PMC12…

I was invited to present on nutrition to surgeons at their annual conference. One of the architects of our current dietary guidelines was in attendance - even so, I didn't hold back. More details in video description. youtu.be/Ip7tZzEZAp0?si…

"In non-statin users, no association was found between increases in LDL-cholesterol levels and risk of all-cause mortality or SCA. However, a decrease in LDL-cholesterol levels during follow-up was associated with a paradoxically increased risk of all-cause mortality."

Nice commentary: "Combined with the findings from the ELSA-Brasil study, these results suggest that very low LDL-C levels may increase all-cause mortality risk in patients with diabetes, regardless of their cardiovascular risk." mdpi.com/2077-0383/14/8…

What about the "bad" LDL cholesterol and apoB? "Higher LDL-C, TC, and TG levels were associated with lower risk of glaucoma." "For each 1-SD increase in apolipoprotein B, the hazard decreased by 5%."

"In a large cohort with more than 30 years of follow-up, we observed a lower risk of hematological malignancy [blood cancer] in relation to a higher level of TC, LDL-C, HDL-C, and ApoAI." link.springer.com/article/10.100…