Edmond Atallah

🔥 Amazing new review on Checkpoint inhibitor-induced cholangiopathy 💊🔥. Thanks to Thanks to @EdmondAtallah @sreeL_k @aly_cratchley and team 👏 👏 🔑 take homes: 1️⃣ It typically occurs after 6-13 cycles of anti-PD-1 therapy 2️⃣ MRCP is crucial to diagnose biliary abnormalities +/- liver biopsy 3️⃣ It has a poor biochemical response to immunosuppression 👀 Check out the full review below fg.bmj.com/content/early/… @PhilSmithIsBack @OTavabie @dr_aditi_kumar @TrevorTabone @eathar_s @IrenePerezMD @KGananandan @zare_benjamin @medicalreg @dtleiberman @BASLedu @BSGtrainees @WorldGastroOrg @ulstergastro @pancreatitis_nl @SEEDendoscopia @EASLedu @AmCollegeGastro @Aegastro @SAGES_updates @UHSEndoscopy @WAGE_media #GITwitter #livertwitter #Endoscopy #ERCP #MedEd #Oncology #Cholangiopathy

Given the increased use in checkpoint inhibitors, it’s critical we continue to gain experience and develop a framework to manage complications. Great review in @FrontGastro_BMJ from Ramu @leeds_liver @TheBileDoc @aly_cratchley Edmond Atallah and colleagues fg.bmj.com/content/early/…

@Shellie_Jean @ibdseb Fantastic congratulations!

Absolutely delighted to be awarded the N-ECCO research grant for 2025 - thank you @ibdseb for the picture. #ECCO2025 #IBD #Research

@Shellie_Jean Congratulations!! Great effort well done

now in print - Substantial cost savings of ultrasound-based management over magnetic resonance imaging-based management in an inflammatory bowel disease service: tandfonline.com/doi/full/10.10…

@wong_yujun @aldomontanoloza @HEP_Journal @JuanAbraldes @ReibergerThomas @elizabeth_verna @NoureddinMD @MattiasMandorf1 @IanARowe @AASLDtweets @AASLDFoundation Congrats my friend well deserved

We have an exciting Clinical Fellow vacancy - closing date 30th May 2024! jobs.nottingham.ac.uk/vacancy.aspx?r…

@MattiasMandorf1 @BavenoCoop Congrats Mattias!

Thanks Annalisa & my regards to all @BavenoCoop friends who collaborated in investigating ACLD after removal/suppression of the primary aetiological factor.

@rabataller Is there any evidence for choosing 60mg in acute AIH or it’s based on historic 1mg/kg?

How to treat AUTOIMMUNE HEPATITIS ? Prof. Manns proposes this algorithm in: - AIH without cirrhosis - AIH with cirrhosis - Acute severe AIH #livertwitter #medtwittwer

@ThisIsButt @esnm_eu @NGMJournal @DipeshVasant @maura_corsetti @NottmBRC @QMULBartsTheLon Great team and congrats on poster!

UK team #NeuroGASTRO2023 @esnm_eu @NGMJournal

🟪NEW Article in press❕ Incidence, risk factors and outcomes of checkpoint inhibitor-induced #liverinjury: a 10-year real-world retrospective cohort study 🔓#OpenAccess at👉bit.ly/43OyRnC @EdmondAtallah #LiverTwitter

Excited to share our results on incidence, risk factors and outcomes of checkpoint inhibitor-induced liver injury ⁦@JHEP_Reports⁩ ⁦@brentocarrigan⁩ ⁦@IOClinicalNet⁩ #LiverTwitter jhep-reports.eu/article/S2589-…

@NadirAbbas_X Enjoy Athens mate and catch up soon

@EdmondAtallah 👏🏽 see you on the other side brother!

It has been a great few days in Larissa discussing difficult AIH and PBC and making new friends! Thanks for organising and see you all soon

@wong_yujun Yours was equally great buddy! Hope to catch up again soon

If you use Immunotherapy or treat the toxicities please fill out our @NIHRresearch @IOClinicalNet survey on IO-induced hepatitis care. Help us learn and improve how to manage patients with this common complication! forms.office.com/Pages/Response… @brentocarrigan @AOlssonBrown #IOCN

For anyone interested in checkpoint inhibitor-induced liver injury (ChILI) please get in touch to join the largest retrospective cohort study in ChILI (uknotch.com/chiliproject)

Holding opposing ideas and the half-life of truth sciencedirect.com/science/articl… @di_martinov @JHepatology

@notadanktar @ebtapper @JHepatology @JesusMBanales It’s open access through this link doi.org/10.1016/j.jhep…

@ebtapper @EdmondAtallah @JHepatology @JesusMBanales How can one have access to full text articles?

Hot take: Methotrexate does not cause liver fibrosis It’s ok to be cautious (periodic fibroscan). It’s ok to use MTX initiation as a trigger to look for fibrosis in at risk people (eg diabetes). But Time to turn the page pubmed.ncbi.nlm.nih.gov/36702175/ @EdmondAtallah #livertwitter

📑 Hepatotoxicity of Immune Checkpoint Inhibitors: What is currently known 💡Highest incidence with triple 💊 💡Incidence similar between dual regimens 💡Risk similar between PD-1 & CTLA-4 inhibitor monotherapy #LiverTwitter #OpenAccess journals.lww.com/hepcomm/Fullte…

Important results highlighting the role of pharmacogenomics in Co-amoxiclav-induced liver injury