Stellar work by Richard @RichardVoit and Vijay @bloodgenes. Congratulations and a great step forward for DBA!
Regulated GATA1 expression as a universal gene therapy for Diamond-Bla... sciencedirect.com/science/articl…
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Craig Forester
14 posts
Craig Forester
@Forester_lab
Science, bikes, fishing. Anything else?
Katılım Temmuz 2021
74 Takip Edilen53 Takipçiler
Deeply honored to receive the 2024 @FNIH_Org Trailblazer Prize! Heartfelt thanks to the incredible lab members past and present, generous mentors, fantastic collaborators, inspiring patients/families, and others who made this possible! 🙏 to my nominator, the amazing Aviv Regev!
Foundation for the National Institutes of Health@FNIH_Org
The FNIH has awarded its seventh annual Trailblazer Prize for Clinician-Scientists to Vijay G. Sankaran, M.D., Ph.D., of @BostonChildrensand @harvardmed. Dr. Sankaran's groundbreaking work in genetics and hematology helped pave the way for a novel sickle cell disease treatment involving the CRISPR gene-editing technology and highlights the innovative spirit of the Trailblazer Prize. Read more here: fnih.org/press-release/…
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@bloodgenes @RichardVoit @UTSWMedCenter @UTSW_PedsHemOnc @CRI_UTSW @utswcancer Congratulations Richard!
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Congratulations, @RichardVoit!!! So proud of you and incredibly excited for this next stage of your journey! Can't wait to follow all the incredible things you will do at @UTSWMedCenter @UTSW_PedsHemOnc @CRI_UTSW @utswcancer and look forward to continuing to work together!
Richard Voit@RichardVoit
Next month the Voit lab will open @UTSW_PedsHemOnc @CRI_UTSW @utswcancer continuing our work studying transcriptional dysregulation in pediatric bone marrow failure and leukemia. Looking to hire at all levels, yes even level 10. Website and official job posting coming soon.
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Craig Forester retweetledi
Craig Forester retweetledi
If I see another paper titled “Single cell RNASeq reveals…”
GIF
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Amazing time at @CUAnschutz with @heide_ford and @Artingerlab. Thanks for inviting me out for cancer center rounds and an amazing ski! Incredible science with old friends and new: @Forester_lab nathan Dahl james degregori meg Macy Josh black amanda winters and many others!
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Craig Forester retweetledi
Please retweet:
I’m happy to be co-organizing this first international meeting on ribosome heterogeneity and specialization! Please register your interest in attending here: forms.royalsociety.org/s/VZ5V3W/.
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@Mauricio_Neuro @RuggeroDavide @sohitmiglani @mbarnalab Expression of these early precursor genes by 4E prevents erythroid maturation and hence expression of genes associated with RBC maturation seen in WT states.
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@RuggeroDavide @Forester_lab @sohitmiglani @mbarnalab Great work! Very interesting. I was wondering what you guys found to be downregulated by the overexpression of eIF4E in your proteomic data, instead of the ones enriched.
Congrats on the great work!
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Congrats Craig @Forester_lab superstar postdoc who led a fascinating study on how specialized translation underlies a differentiation program of red blood cells. Thanks to @sohitmiglani @mbarnalab Al Burlingame Juan Oses and all team! science.org/doi/10.1126/sc…
Venice, Veneto 🇮🇹 English
@Mauricio_Neuro @RuggeroDavide @sohitmiglani @mbarnalab The proteomics show WT expresses many genes associated with erythroid maturation (globin, RBC cytoskeleton) while these are not seen in eIF4E. We believe this shows 4E selectively expresses genes in early precursor states.
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@Mauricio_Neuro @RuggeroDavide @sohitmiglani @mbarnalab Thank you for your comment Mauricio! The analysis we did is looking at relative gene expression between the wild-type and eIF4E overexpression state after 3 days of maturation induction by changing the cytokine milieu.
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Very excited to share a story looking into translational control in the early steps of erythroid commitment. Thank you to @mbarnalab, @RuggeroDavide, the editorial staff at @ScienceMagazine and our great collaborators.
science.org/doi/10.1126/sc…
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Craig Forester retweetledi
Thanks @WilburLam for headlining the Taru Hays Hematology Symposium @ChildrensColo and @NucleatedRBC @Forester_lab for organizing. A much needed few days to focus on great research and reconnecting with colleagues.
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Craig Forester retweetledi
How are vaccines holding up against Delta?
Updated table with latest data, including new J&J trial.
Notable is the decline for protection of mRNAs vs infections (still very solid vs hospitalizations and deaths)
More on that in 🧵below twitter.com/EricTopol/stat…
Eric Topol@EricTopol
An update on Delta, vaccination protection and viral loads from the aggregate data available, with new @PHE_uk data 1. Delta infections are characterized by very high viral loads (low Cts). When a breakthrough occurs, the load is similar to unvaccinated, but clears more rapidly
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A fascinating link between p53 control of selective translation to guide early development in a model of ribosomopathy. Congrats @geraldctiu and @mbarnalab!!
authors.elsevier.com/c/1dNDf5Sx5gmJ…
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