Gargi Mahajan

The moon affects biology in ways that are still largely mysterious. The biochemistry of the muted moonlight phenomenon was not studied until recently. “It was always the sun versus darkness,” said the biochemist Eva Wolf. quantamagazine.org/how-this-marin…

Delighted to share our study on niacin receptor structure & signaling-bias published in @NatureComms !! Spearheaded by our amazing team including @manish31247914, @ParishmitaSarm2, @RamanujBanerje5 and several other members in our laboratory @IITKanpur !! nature.com/articles/s4146…

Delighted to share our study on probing the conformational diversity in GPCR-beta-arrestin complexes !!! A genetically-encoded nanobody sensor reveals conformational diversity in beta-arrestins orchestrated by distinct seven transmembrane receptors biorxiv.org/content/10.110…

New work from our lab unveiling the development of Ib32 as a novel sensor in detecting GPCR activated β-arrestin conformations! Congratulations to our mentor @arshukla for his guidance and all the authors involved. 🥳 biorxiv.org/content/10.110…

GPCRs represent one of the most diverse superfamily of receptors and two isoforms of beta-arrestin regulate their signalling. We report the atypical modes of b-arrestin interaction with two distinct receptors, M2R and ACKR2 (D6R). #acknowledgments" target="_blank" rel="nofollow noopener">science.org/doi/10.1126/sc…

Extremely happy to share our recent work on β-arrestins!!!!! Here we visualize the atypical interaction of βarrs with 7TMRs and also show the structural transition of the carboxyl terminus of βarr2 from a β strand to an α helix upon activation by D6R. science.org/doi/10.1126/sc…

Elated to share our new work showcasing the atypical modes of β-arrestin interaction with seven transmembrane receptors | @ScienceMagazine @the_rarejm @ParishmitaSarm2 @manish31247914 @GargiM09 Prof @arshukla science.org/doi/10.1126/sc…

Delighted to share our labs latest work highlighting the complex world of arrestin - 7TMRs interactions. Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors | Science science.org/doi/10.1126/sc…

Excited to share a recent study from our lab highlighting the atypical modes of β-arrestin interaction with seven transmembrane receptors. @arshukla @the_rarejm @ParishmitaSarm2 @manish31247914 @RamanujBanerje5 @Sayantanxahas @GargiM09 science.org/doi/10.1126/sc…

Delighted to share our study on 7TMR-β-arrestin interaction, activation, and signaling, now published in Science @ScienceMagazine!!! Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors | Science science.org/doi/10.1126/sc…

Excited to share a recent publication from our lab revealing intricate interactions between β-arrestin and GPCRs. @ScienceMagazine @arshukla @the_rarejm @ParishmitaSarm2 @manish31247914 @RamanujBanerje5 @Sayantanxahas science.org/doi/10.1126/sc…

Happy to share this piece published in Science Signaling @scisignal ! It was great working with their fantastic editor @foleyjf on this ! The expanding footprint of basic biology research in India | Science Signaling science.org/doi/10.1126/sc…

Let's explore the frontiers of #BiologicalSciences together! #iitkanpur BSBE winter symposium

@mahas999 @iiserbhopal @arshukla @India_Alliance It's an honor to host Dr. Jyothilakshmi Vadassey from @NIPGRsocial, New Delhi! She is set to inspire us with insights on Understanding the molecular mechanisms of plant-microbe interactions to improve insect control strategies. 🌿 #IITKanpur @EMBO @EMBO_YIP @arshukla

⚠️#NewPaperAlert 𝐀d𝐯a𝐧c𝐞s i𝐧 𝐭h𝐞 𝐫e𝐜o𝐧s𝐭r𝐮c𝐭i𝐨n o𝐟 𝐭h𝐞 𝐬p𝐢d𝐞r t𝐫e𝐞 𝐨f l𝐢f𝐞: A r𝐨a𝐝m𝐚p f𝐨r s𝐩i𝐝e𝐫 𝐬y𝐬t𝐞m𝐚t𝐢c𝐬 𝐚n𝐝 𝐜o𝐦p𝐚r𝐚t𝐢v𝐞 𝐬t𝐮d𝐢e𝐬 By Siddharth Kulkarni, @hannah_m_wood and, @GustavoHormiga onlinelibrary.wiley.com/doi/full/10.11…

Congratulations to @arshukla, @manish31247914, @RamanujBanerje5, @the_rarejm, @saha_shirsha, @ParishmitaSarm2, and other authors involved. 🎉

An exciting paper from our lab describing nine cryo-EM structures to shed light on the secrets of complement anaphylatoxin receptors C3aR and C5aR1! cell.com/cell/fulltext/…

An exciting paper from our lab describing nine cryo-EM structures to shed light on the secrets of complement anaphylatoxin receptors C3aR and C5aR1! cell.com/cell/fulltext/…

Delighted to share our study on complement anaphylatoxin receptors published in Cell @CellCellPress!!! Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors: Cell cell.com/cell/fulltext/…

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