Sifeng Gu, PhD retweetledi
Precise, minimally evolved adenine base editors generated through mutation reversion analysis go.nature.com/4rHWkmu
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Sifeng Gu, PhD
32 posts
Sifeng Gu, PhD
@GuSifeng
Ph.D. from @Komorlab | UCSD Chemistry & Biochemistry | Genome Editing
San Diego, CA Katılım Ekim 2018
90 Takip Edilen65 Takipçiler
Sifeng Gu, PhD retweetledi
🚀 So excited to share that our manuscript on Multiplexed Orthogonal Base Editor (MOBE) systems is now online! Honored to have helped Quinn @Quinn_Cowan_sci on this amazing project, which combines the best of ABE and CBE. It was a truly fun and rewarding journey!
Quinn Cowan, PhD@Quinn_Cowan_sci
Excited my PhD work is out now @NatureBiotech! We report Multiplexed Orthogonal Base Editor (MOBE) systems: tools to simultaneously install distinct point mutations. MOBEs introduce co-occurring genetic variants (polygenic disease, haplotypes)🧬 🧵⬇️ 1/ go.nature.com/3K8Kfn1
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@annikalikeschem Thanks! You also did great work in this project! So congrats on you too😏
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Really enjoyed #deaminet2023 ! Great to hang out with the lab and many outstanding scientists during the conference! Please stay tuned for more upcoming work on base editing mechanisms.
Komor Lab@KomorLab
Greetings from Palm Springs! The whole lab had a great time at #deaminet2023. Wonderful to hear about all the amazing science being done in the field of #baseediting. Special shout out to @GuSifeng who crushed his talk yesterday!
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Sifeng Gu, PhD retweetledi
Sifeng Gu, PhD retweetledi
We are excited to share Double Tap with you all in @NatureComms! In collaboration with @ValentinoGantz, we show that HDR can be improved using secondary gRNAs that target indel byproducts. Congrats to @Zsolt_Bodai and @bishop_alena!
rdcu.be/cM9S1
rdcu.be/cM9SR
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Sifeng Gu, PhD retweetledi
Congrats to our amazing postdoc @Zsolt_Bodai who had been named a #CottrellFellow! This award will support Zsolt as he continues his research to uncover the mechanisms by which base editors work and gains undergraduate teaching experience. rescorp.org/news/2021/09/r…
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We first review deoxyuridine, deoxyinosine, and single-stranded break repair. Then, we discuss how interactions among these different repair processes can lead to different base editing outcomes. Hope this would be helpful and feel free to exchange any thoughts with us! 2/2
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Super stoked that this review got published. It was a really fun journey writing this with @Zsolt_Bodai, @Quinn_Cowan_Sci and our boss Alexis @KomorLab. To our knowledge, this is the first review paper that focuses on discussing DNA repair mechanisms involved in base editing! 1/2
Komor Lab@KomorLab
Check out our new review by @GuSifeng @Zsolt_Bodai and @Quinn_Cowan_Sci that discusses the potential DNA repair mechanisms that process base editor intermediates! sciencedirect.com/science/articl…
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Proud to be part of this! Say no to racism, prejudice and inequality.
Komor Lab@KomorLab
In observance of of #ShutDownSTEM we have drafted a Statement of Support for the #BLM movement with a list of actions we will take to combat racism and enforce equity and diversity in our community #BlackLivesMatter #ShutDownAcademia @UCSDChemBiochem @AcademicChatter @UCSDPhySci
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@KomorLab Thanks all of my excellent lab mates for the support !
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Sifeng Gu, PhD retweetledi
Sifeng Gu, PhD retweetledi
Happy to publish with my Indigenous Brothers & Sisters (again). Mandatory quarantine reading for anyone working in genomics, information policy, or #datascience @UNGlobalPulse @ResearchUCSD @ObamaFoundation 💻🧬
Global Indigenous Data Alliance (GIDA)@GidaGlobal
Rights, interests and expectations: Indigenous perspectives on unrestricted access to genomic data | Nature Reviews Genetics. nature.com/articles/s4157…
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Big shout out for Dr Zhong and my undergrad institute the University of Edinburgh!
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Sifeng Gu, PhD retweetledi
Lab happy hour to celebrate @CA_Vasq receiving a #FordFellowship! Awesome news in an otherwise not-so-awesome time. #DiversityInSTEM
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Sifeng Gu, PhD retweetledi
Congratulations to @Quinn_Cowan_Sci (pictured here with his remote exam setup) for passing his 2nd Year Departmental Exam!!! 🥳 #StaySafeStayHome #RemoteScience
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Sifeng Gu, PhD retweetledi
A big thank you to @NHMLA for inviting Alexis and the Komor Lab to #FirstFridays where Alexis discussed the future of medicine alongside @Blazing_Science and pulitzer prize writer @pattmlatimes. Until next time! #thefutureisnow @UCSDPhySci
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Sifeng Gu, PhD retweetledi
Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19 - The Lancet thelancet.com/journals/lance…
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