Sabyasachi Senapati

Is this farmhouse from you @dominos_india ? Pathetic.

The complement system in intestinal inflammation and cancer As part of JCI’s Review series on complement biology and therapeutics, Carsten Krieg & Silvia Guglietta @GugliettaLab @MedUnivSC et al. highlight the complement system in the GI tract under homeostasis, #inflammation, and during tumor development, progression, and treatment: jci.org/articles/view/…

An inheritance of long life science.org/doi/10.1126/sc…

New online! Defining the mucosal ecosystem: epithelial–mesenchymal interdependence in gastrointestinal health and disease bit.ly/46t7cx3

Now online! IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity dlvr.it/TN04V7

IL-25-induced memory ILC2 enforce mucosal immunity @CellCellPress cell.com/cell/fulltext/…

Nature research paper: Ancient DNA connects large-scale migration with the spread of Slavs go.nature.com/45UUllG

🧬Multiplexed Assays of Variant Effect (MAVEs) generate functional data for thousands of variants in a single experiment, accelerating VUS reclassification and improving patient care. #MAVEs #Genomics Explore the latest advances in MAVE technologies: nature.com/articles/s4157…

Clock genes keep intestinal ILC3s ticking bit.ly/4n7pnOu

GWASs have revealed thousands of disease-associated variants. To translate them to therapies we need to know how they act. Historically we linked variants to molecular traits (eQTLs, pQTLs...) in human tissue. Now it’s increasingly feasible to test them in iPSC-derived cells👇

Your DNA sequence reveals a rare mutation. Will you get the disease, i.e. penetrance? A new study using machine learning predicts this across 10 common diseases, 1,600 genomic variants @IcahnMountSinai @IcahnInstitute @ScienceMagazine science.org/doi/10.1126/sc…

Our SEPTEMBER ISSUE is live! CRC health disparities, gut microbiome in MASLD, intestinal pH, oesophagus immunology, and much more! nature.com/nrgastro/volum…

Gut microbiota-specific T cell subset drives CNS inflammation dlvr.it/TMjGRZ #immunology

🧫 Researchers at @UWMadison introduced a method of co-culturing adult feline small intestinal organoids with growth-inhibited human foreskin fibroblast feeder cells to enhance organoid proliferation and survival. @mSphereJ | bit.ly/41Au1Mq

Stromal cell–derived chemokines modulate immune cells in inflammation: New findings and future perspectives @J_Immunol #google_vignette" target="_blank" rel="nofollow noopener">academic.oup.com/jimmunol/advan…

50,000 years of evolutionary history of India: Impact on health and disease variation: Cell cell.com/cell/fulltext/…

How gut inflammation can induce brain inflammation nature.com/articles/s4158… @Nature

Piezo1 regulates colon stem cells to maintain epithelial homeostasis through SCD1-Wnt-β-catenin and programming fatty acid metabolism. Check out the full study by @2024_HUST Jun Song & colleagues in @CellReports #ISSCR2025 hubs.li/Q03rG5vD0

The unintended consequences of a gut microbiome transplant cell.com/cell/abstract/…

New online! Genomics of host–microbiome interactions in humans bit.ly/4dIWPHq