
Jacob Trefethen
2K posts

Jacob Trefethen
@JacobTref
OpenAI Foundation science!




NEW BLOG! @RuxandraTeslo, @kroetscha, @vientsek, @NeuroStats, and I have started a joint blog on Clinical Trials Abundance! We'll aim to publish weekly thoughts, commentary and ideas on how to make clinical trials more efficient & abundant. Subscribe: clinicaltrialsabundance.blog



The AI usage was really interesting. I got that "AI feeling" a bunch of times in reading entries (which tended to check out in Pangram), but the underlying ideas were often good and well expressed, so we decided to ignore it in scoring




Life update: after an incredible year at Noetik, I’ve joined the OpenAI Foundation (@FoundationOAI) to help create its "Public Data for Health" program. The OpenAI Foundation is a well-capitalized philanthropy, and a meaningful share of its funds will be committed to building and opening up the datasets necessary to massively accelerate biomedical research. Some of our grants will go toward efforts to relieve known data bottlenecks, but others will be more speculative, made on the premise that artificial intelligence is currently reshaping how scientific discovery happens, and that this reshaping will surface fundamentally new data bottlenecks of its own. We have a long to-do list ahead of us, and I’m ecstatic to be joining @JacobTref on this effort! On writing: I’ve spent the last few years covering the intersection of AI with many, many subfields of the life sciences at owlposting.com, and it will continue + remain independent. Many exciting essays and podcasts are planned! Lastly, I remain extremely optimistic on Noetik and am very thankful for my time there. Consider following @Ronalfa and @recursus to stay updated on their efforts!


Today, we're launching RAISE US. America has a technology strategy for AI. It doesn't have a people strategy yet. We're here to build one. RAISE US is co-chaired by @GinaRaimondo and Eric Holcomb. We're working with governors, employers, and educators to help workers train, transition, and thrive. This works because the people building AI and the people most affected by it are at the same table. Read more: raiseus.ai #RAISEUS

Life update: after an incredible year at Noetik, I’ve joined the OpenAI Foundation (@FoundationOAI) to help create its "Public Data for Health" program. The OpenAI Foundation is a well-capitalized philanthropy, and a meaningful share of its funds will be committed to building and opening up the datasets necessary to massively accelerate biomedical research. Some of our grants will go toward efforts to relieve known data bottlenecks, but others will be more speculative, made on the premise that artificial intelligence is currently reshaping how scientific discovery happens, and that this reshaping will surface fundamentally new data bottlenecks of its own. We have a long to-do list ahead of us, and I’m ecstatic to be joining @JacobTref on this effort! On writing: I’ve spent the last few years covering the intersection of AI with many, many subfields of the life sciences at owlposting.com, and it will continue + remain independent. Many exciting essays and podcasts are planned! Lastly, I remain extremely optimistic on Noetik and am very thankful for my time there. Consider following @Ronalfa and @recursus to stay updated on their efforts!




Delighted to share that Frontier has raised an additional $915 million to accelerate the world’s best carbon removal companies. frontierclimate.com/writing/growth…


Today, the OpenAI Foundation is committing $50M to the 2026 People-First AI Fund to fund trusted, community-based nonprofits exploring how AI can expand access and opportunity across essential services, arts and culture, and media and journalism. Applications are now open through July 15. Learn more about what we’re looking for, eligibility criteria, and how to apply: openaifoundation.org/news/2026-peop…


AI is advancing quickly. Society’s ability to manage its risks must advance just as fast. Today we’re sharing our vision for AI Resilience, with more than $130M in initial grants underway across bio-resilience, cyber-resilience, AI model safety, and AI’s impact on young people: openaifoundation.org/news/resilienc…







