Jonathan Davis, MD, MPHS

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Jonathan Davis, MD, MPHS

Jonathan Davis, MD, MPHS

@JonathanDavisHF

Director @sfhealthnetwork HF Program Zuckerberg SF General Hospital @zsfgcare @ucsfcardiology. New Dad x2! Alum @WUSTLmed⬅️ @UCSFmedicine⬅️ @cornell he/his/him

San Francisco, CA Katılım Nisan 2014
586 Takip Edilen3.1K Takipçiler
Jonathan Davis, MD, MPHS retweetledi
Ahmed Bennis MD 🫀
Ahmed Bennis MD 🫀@drbennisahmed·
💊🫀 What does optimal therapy actually buy a 65-year-old with HFmrEF/HFpEF? From Nature Medicine (Vaduganathan et al., 2025): 🔴 SGLT2i + nsMRA → +3.6 years event-free survival 🔴 SGLT2i + nsMRA + ARNI → +4.9 years (LVEF <60%) vs. standard therapy alone. Nearly 5 extra years without hospitalization or death. 💡 These drugs exist. They work. Are all eligible patients receiving them? Vaduganathan et al. Nature Medicine, Oct 2025 @mvaduganathan #HeartFailure #HFpEF #HFmrEF #SGLT2i #ARNI #Cardiology #MedTwitter #NatureMedicine
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Gregg Fonarow MD
Gregg Fonarow MD@gcfmd·
Why are 100% of eligible patients with HFrEF w/o CI or intolerance not receiving quadruple GDMT in 2026? ARNI+BB+MRA+SGLT2i ➡️ 75% ⬇️ all-cause ☠️ (26% ARR, NNT=4, 24 months) 85% ⬇️ HF 🏨 (33% ARR, NNT=3, 24 months) Extend median survival by 7-11 years 💊 Cost $78/month
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Gregg Fonarow MD
Gregg Fonarow MD@gcfmd·
HFrEF in 2026 Most common Rx is use still ACEI/ARB+BB, despite Class 1 recommendation for quadruple GDMT ACEI/ARB+BB ➡️ ARNI+BB+MRA+SGLTi Extends median survival: 6.3 years 75.6 months 2300 days 55,188 hours 3,311,280 minutes 💊s cost extra $70 per month Worth it?
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Gregg Fonarow MD
Gregg Fonarow MD@gcfmd·
Considerations for Rx beyond the foundational 4 pillars of disease modifying guideline-directed medical therapy for HFrEF
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Steve Greene
Steve Greene@SJGreene_md·
@AndrewFoy82 @gcfmd @mvaduganathan @AndrewJSauer @dranulala @ShelleyZieroth @JavedButler1 @pedschwartzmann @JonathanDavisHF @HFA_President @ankeetbhatt To Mandrola's original point: 🔑is definition of "decompensated" We should not initiate BB in hemodynamic instability/shock But "decompensated" is not synonymous w/ entirety of a HF hospitalization. In-hospital/pre-discharge initiation BB is evidence-based routine approach.
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Jonathan Davis, MD, MPHS retweetledi
Jonathan Davis, MD, MPHS
Jonathan Davis, MD, MPHS@JonathanDavisHF·
9/29 I start at Mercy St. Louis! Working at @UCSFHospitals/@ZSFGCare/@UCSFCardiology was a profound privilege. The community, patients, & colleagues gave me more than I can ever express. Please know how grateful I am to have been part of this extraordinary team.
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Nosheen Reza, MD, MS
Nosheen Reza, MD, MS@noshreza·
Pop in for any part of the hour — we’re excited to connect with you and chat about the amazing things we have going on at @JCFINT! @HFSA @JasonKatzMD @ElliottMillerMD @SarahChuzi @ShahzebKhanMD @JulieDoberne @hcg_md @Carnicelli_Ant @MartyTamMD @JonathanDavisHF @FarhanRazaMD
JCF Intersections@JCFINT

Join Editor in Chief @JasonKatzMD and Deputy Editor @noshreza for JCF-I Office Hours! Answering your questions on: ✅the journal’s inaugural publications ✅what they are looking for in submissions ✅exciting updates on what’s to come 🔗 Registration: bit.ly/3Hu9SRo

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Diego Segura-Rodríguez
Diego Segura-Rodríguez@SeguraCardio·
🚨🚨🚨 Just released: 2025 AHA/ACC Multisociety Guideline on High Blood Pressure in Adults‼️ A must-read update for all clinicians. Love this post? I appreciate sharing & following ❤️ #Hypertension #CardioTwitter #HTN2025 #AHA
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