Josh Griffiths retweetledi
Monoallelic IFT140 Variants Causing Childhood-Onset Autosomal Dominant Polycystic Kidney Disease
bit.ly/3J9ZIWT
@JoshDGriffiths @CamyLG86
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Josh Griffiths
33 posts
Josh Griffiths
@JoshDGriffiths
Renal SpR and MRC/KRUK Clinical Research Training Fellow in Renal Medicine at the University of Sheffield. ADPKD genetics. Man City FC
Katılım Kasım 2019
165 Takip Edilen49 Takipçiler
I can now officially announce that I have been awarded a @Kidney_Research intermediate fellowship to investigate ARPKD proteins! I am grateful for the opportunity and look forward to the next 3 years of research! #ARPKD #PKD
kidneyresearchuk.org/2024/06/12/stu…
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Josh Griffiths retweetledi
In this trial involving patients with chronic kidney disease, empagliflozin resulted in a lower risk of disease progression or death from cardiovascular causes than placebo. #KidneyWk nej.md/3Nol806
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Josh Griffiths retweetledi
Delighted to share our recent publication.
A founder UMOD variant is a common cause of hereditary nephropathy in the British population.
Thank you to all who helped with this work!
@mkvalluru
jmg.bmj.com/content/early/…
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Josh Griffiths retweetledi
Josh Griffiths retweetledi
The second project funded as part of our partnership with @PKDCharity is that of Professor Albert Ong.
Professor Ong is on a mission to discover and test new treatments for ADPKD, building on some of his existing work in the area.
Read more 👇
bit.ly/3QTbDY4
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Josh Griffiths retweetledi
Congratulations to Professor Albert Ong of @sheffielduni for winning the 2022 Lillian Jean Kaplan International Prize for Advancement in the Understanding of Polycystic Kidney Disease (PKD) - an amazing achievement.
sheffield.ac.uk/news/internati…
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Josh Griffiths retweetledi
Congratulations to Dr. Alessandra Boletta and Dr. Albert Ong for being the recipients of the Lillian Jean Kaplan International Prize honoring individuals for excellence and leadership in PKD clinical and basic research. #endPKD #PolycysticKidneyDisease
Int Society of Nephrology@ISNkidneycare
@ananthmsn34 🏅 Dr. Alessandra Boletta (@Boletta_Lab) and Dr. Albert Ong Winners of the Lillian Jean Kaplan International Prize
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Delighted to have been offered this fellowship. Excited to start! @Ong_Lab
Kidney Research UK@Kidney_Research
Research in focus 🔍 With our funding, Dr Joshua Griffiths from @sheffielduni will try to understand how the stiffness of the skeleton of cells affects cyst growth in patients with ADPKD - a leading cause of kidney failure. Read more 👉 bit.ly/3Ie8yx2.
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Josh Griffiths retweetledi
1) Welcome to this #accredited #tweetorial on #cardiovascular disorders in Autosomal Dominant Polycystic Kidney Disease. #ADPKD is widely recognized in assoc w/risk of #CKD, but has protean #cardiovascular effects as well. Expert author @dguerrot of @CHURouen 🇫🇷 leads us!
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Josh Griffiths retweetledi
Inducible disruption of cilia-related genes in mice results in slowly progressive cystic disease, which is accelerated by renal injury. This study shows that adaptive immune cell subtypes contribute to injury-accelerated cystic kidney disease in mice bit.ly/j2021030278
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@RenalDocGillis @SheffieldHosp Congratulations! Very well deserved!
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Over the moon at being appointed as consultant nephrologist at Sheffield Kidney Institute. Dream job and feel very lucky! Can’t wait to get started in March! @SheffieldHosp #renal #womeninnephrology #homedialysis
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Absolutely delighted to be offered this KRUK/MRC clinical training fellowship! I'll be exploring why cysts develop and novel therapeutics in ADPKD. Can't wait to get started! @Ong_Lab #ADPKD @PKDCharity @The_MRC
Kidney Research UK@Kidney_Research
New research grants awarded 🗞️ After another difficult year, we are delighted to have been able to still award grants for new research that will contribute in the fight to end kidney disease. More information below 👇 bit.ly/3rNCoS4
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Josh Griffiths retweetledi
And our photo competition winner is...
Dr Laura Wilson's stunning image of macrophages (purple), kidney tubules (green) and lymphatic vessels (white) in a developing kidney🏆
📸‘More than just tubules – the importance of the immune system in growing a kidney’.
#KidneySnapshots
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Josh Griffiths retweetledi
Excellent collection of reviews in a special edition of Cellular Signalling on many aspects of ADPKD (including some from members of our own group!)
Complimentary access for a limited time so get them while you can! 😉 #pkd #KidneyDisease
sciencedirect.com/journal/cellul…
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Josh Griffiths retweetledi
We are delighted to share our latest publication!
We report on a novel interaction between PC1 and the specific RhoGAP proteins (ARHGAP35) in the regulation of Centrosomal RhoA activation and ROCK signalling.
pubmed.ncbi.nlm.nih.gov/32663194/
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Josh Griffiths retweetledi
Correspondence — Retraction: Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19. N Engl J Med. DOI: 10.1056/NEJMoa2007621. nej.md/2XZnLMJ
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Josh Griffiths retweetledi
Our new pre-print is out!
Along with our collaborators at @ImperialImmuno @UHN , we identify a subset of urinary exosomal miRNAs that could serve as novel biomarkers of disease progression and suggest new therapeutic targets in ADPKD.
Thanks everyone!
sciencedirect.com/science/articl…
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