Julia Morud Lekholm

What a great evening it was 🎹 🐈

Our latest manuscript is out for early release! Thank you to @JuliaMorud @AmyCourtneyy and @LabSchafer for another successful collaboration 🎊 A Novel and Functionally Diverse Class of Acetylcholine-gated Ion Channels jneurosci.org/content/early/…

Last day today to apply to two open postdoc positions in my group in Gothenburg, Sweden. 2+1 year contract at a department with great resources and super collaborators! Please share! web103.reachmee.com/ext/I005/1035/…

Neat paper from BTI's Schroeder lab and colleagues at MRC LMB and KU Leuven describes how betaine acts to control behavioral states in C. elegans 🪱 @group_schroeder @jingfang_yu @MRC_LMB @CornellCAS @KU_Leuven @PNASNews @JuliaMorud @IHardege @LabSchafer pubmed.ncbi.nlm.nih.gov/36413500/

It's true - catching up with @IHardege & @JuliaMorud at #SfN2022 was definitely one of my highlights! brown.edu/carney/news/20…

Excited to be able to share this now! Worms learn to avoid odors that they smell during starvation. In our new paper, we describe how insulin/IGF signaling in a single olfactory neuron can generate the aversive memory needed for this type of learning. cell.com/cell-reports/f… 1/5

Our latest paper describing a betaine-gated ion channel involved in controlling behavioural states is now out in @PNASNews! @IHardege spent many many months on those food search traces! Great collaboration between @LabSchafer and @group_schroeder. pnas.org/doi/10.1073/pn…

We now have 2 open postdoc positions in my lab, please spread the word to people interested in worms, ion channels and signal transduction. web103.reachmee.com/ext/I005/1035/…

Finally out! Check our new resource of neuropeptide-GPCR interactions in C. elegans. We identify 461 peptide-GPCR pairs that allow mapping peptidergic circuits. See also this application on the worm's peptide connectome doi.org/10.1101/2022.1… Resource: doi.org/10.1101/2022.1… 🧵

Finally out! Proud to present the collaborative effort where we systematically mapped neuropeptide-GPCR interactions biochemically (doi.org/10.1101/2022.1…) and constructed an in silico map of neuropeptide signaling in the worm brain doi.org/10.1101/2022.1…

@wormychew I particularly loved your shoutout to the other #postdocs at @MRC_LMB & comments on changing #ResearchCulture - so thankful we had @Denise_S_Walker @IHardege @JuliaMorud @isabelbeets @EvaKaulich @Genes_GigglesDr & others! I treasure the #fellowship of #femalescientists we built

I am honoured to be appointed as a 2022 ”Research Leader of the Future” by @strategiskaSSF, giving me the opportunity to expand my research group. strategiska.se/en/they-are-th… Send potential PhD/postdocs in biochem/neuro my way since several openings will be coming up in autumn!

Neuropeptide signalling shapes feeding and reproductive behaviours in male C. elegans biorxiv.org/cgi/content/sh… #biorxiv_neursci

important work that explains why gap junctions should always be taken into consideration and why ablation and inhibition of a neuron could result in two opposite effects

Excited to say that Aylesse Sordillo’s thesis work is published! It shows that one neuron shapes behavior both when active and when silent. Active, mostly through chemical synapses. Silent, through gap junctions that stabilize an opposing circuit state. elifesciences.org/articles/67723

@wormychew @group_schroeder @IHardege @LabSchafer That question remains to be established in the follow up paper! Also @IHardege really deserves most of the credit for this paper, quantifying that phenotype was far from easy and straightforward.

Check out our latest preprint! We show betaine to be a real transmitter and describe a role for it in vivo! We also identify a pathway for neuronal production of betaine. Great collaboration with the Schroeder lab! @group_schroeder @IHardege @LabSchafer biorxiv.org/content/10.110…

Our latest preprint is just out! We discover that betaine acts in the nervous system of worms to alter their behaviour, cool right?! Another great team project from @labschafer & @juliaMorud

Check out this very nice dispatch in Current Biology @CurrentBiology of our recent publication written by Catharine Rankin @wormslearn and Alex Yu. cell.com/action/showPdf…

@wormychew @IHardege @LabSchafer Same!