Julie Qiaojin Lin

Huge congratulations to Christine! Very well-deserved recognition for her truly courageous and innovative research on axon guidance and local translation, and for being an inspiring mentor to the younger generation of neuroscience lovers!

Finally out! We found that mRNAs are not uniformly distributed across the cytoplasm. mRNA architecture is the strongest determinant for localization. Subcytoplasmic location of translation controls protein output. cell.com/molecular-cell…

Looking for an exciting postdoctoral position? Have skills or interest in rodent neurophys, opto, olfaction and sleep? Want to live in London and work at the amazing @SWC_Neuro? DM me and let’s chat at #SfN2023! #postdoctoral-research-fellow-harris-lab-2-posts" target="_blank" rel="nofollow noopener">sainsburywellcome.org/web/content/cu…

What is the link between hibernation and neurodegeneration? How could a cold-resistance protein pave the way for new dementia treatments? The UK DRI's @JulieQLin & @DeepakKhuperkar spoke to @OpenTargets about their research into a key protein, RBM3⬇️ blog.opentargets.org/rbm3-research-…

What is the link between hibernation and dementia treatments? This is the question that @JulieQLin and @DeepakKhuperkar try to answer in their latest project — we chatted to them to find out more blog.opentargets.org/rbm3-research-…

#HNRNPH1 regulates expression of the #neuroprotective cold-shock protein #RBM3 through poison exon exclusion @JulieQLin @DeepakKhuperkar et al @MallucciLab @RueppLab embopress.org/doi/full/10.15…

Christine Holt, 2023 Brain Prize winner giving her Prize Lecture: Brain wiring and local translation in axons. Introduced by Richard Morris, Chair of The Brain Prize selection committee. #BrainPrize #neuroscience #science

Happy to share the first paper from our @UKDRI Cross-Centre project with @MallucciLab in collaboration with @ule_lab and Metzakopian lab led by the amazing @JulieQLin and @DeepakKhuperkar. embopress.org/doi/full/10.15….

🚨 Hot off the press! A @UKDRI analysis of an Open Targets screen delves into the regulation of the RBM3 cold-shock protein, identifying HNRNPH1 as a potential neuroprotective target Congratulations to first authors @JulieQLin and @DeepakKhuperkar!

Interested in understanding how neurons transport mRNAs in dendrites and control when and where they're used for local protein synthesis? My group is hiring a postdoctoral researcher! elxw.fa.em3.oraclecloud.com/hcmUI/Candidat…

Scientists at the UK DRI at Cambridge have used gene therapy to increase levels of ‘cold shock protein’ in the brains of mice, protecting them against prion disease. If we could replicate this in humans, it could be a way to prevent neurodegeneration👉buff.ly/3ns4kwf

I am very excited and looking forward to start my own research team @FGA_lab @VUamsterdam soon to study neuronal mRNA trafficking and axonal translation. I am looking for a PhD candidate to strengthen this team so get in touch if you are interested! workingat.vu.nl/ad/phd-candida…

mRNA transport, translation, and decay in adult mammalian central nervous system axons cell.com/neuron/fulltex…

@Hovy_Wong @MpiBrain @PDA_PhD @Marc_vOo @elkutsarova @TheSomnolentSci @fcylee That was an absolutely amazing Hovy talk with impressive images and movies, as always!!

@MpiBrain @PDA_PhD @Marc_vOo @elkutsarova @TheSomnolentSci And of course thank you to some old friends & colleagues who spared time to join! e.g. @fcylee & @JulieQLin who I saw real quick ;)

Had a lovely time presenting @MpiBrain. Great Qs & stimulating discussions on RNA, local translation, plasticity, preNMDARs with @PDA_PhD @Marc_vOo @elkutsarova @TheSomnolentSci and others! Thank you @elkutsarova & mEPSCs committee for organizing, & @TheSomnolentSci for hosting!

Do you want to learn more about the axonal endoplasmic reticulum and about local translation? Have a look at our new preprint! biorxiv.org/content/10.110…. @UniUtrecht @ginny_farias Lab. A🧵

Can we target alternative splicing to treat neurodegenerative diseases? With @MallucciLab and @OmiqaBio we find that a poison exon is responsible for cold induced RBM3 expression. Targeting this exon by ASO-therapy results in neuroprotection in vivo. biorxiv.org/content/10.110…

Meanwhile, also check out another collaborative project between @Malluccilab and Heyd lab @pre_mRCO, for neuroprotection upon RBM3 induction using ASOs. biorxiv.org/content/10.110…

Now you may have another question: how does RBM3 protect neurons? We will leave this story for another time. Stay tuned!

Ever wonder what happens to our brains at lower temperatures? Looks like our neurons enjoy a cool bath – thanks to increased expression of a cold-shock protein, RBM3. Check out our preprint sharing some secrets behind RBM3 cold induction. biorxiv.org/content/10.110…