Shingo Kajimura Lab

Online Now: Flip the fuel, and the heat is on! Carnitine synthesis as a physiological mediator of fuel adaptation dlvr.it/TRr9J0 #trends #endocrinology #metabolism

Please help us share this information with colleagues who might be interested. Thanks! hhmi.wd1.myworkdayjobs.com/en-US/External…

An excellent review of our recent paper on mitochondrial control of fuel switching – thank you!! The bottleneck of fat burning | Science science.org/doi/10.1126/sc…

To our surprise, the carnitine biosynthesis pathway influences the optimal efficacy of GLP1-based anti-obesity therapies! You can see the full MS here until it lasts: science.org/eprint/ARC749J….

Our body (cells) have fuel preference, e.g., burning fat vs. carbohydrates, which depends on the environment and nutritional states. How do cells decide which fuels to use?  Our new study found that carnitine biosynthesis is crucial for fuel switching science.org/doi/10.1126/sc…

@LabSaltiel Congratulations!!!!!

Congrats to Postdoc Danny Son and all of our colleagues and collaborators on this paper.

Neutrophil-derived IL-1β preserves lipid stores during metabolic stress, highlighting a physiological function of innate immune cells in limiting lipid loss and maintaining energy homeostasis @Nature @UCSDMedSchool @LabSaltiel nature.com/articles/s4158…

Calling all rising juniors & seniors: Interested in biological or biomedical research? Apply now for our ’26 Summer Undergraduate Research Experience Program! Nine weeks, hands-on research, & mentorship from some of the nation’s top scientists — learn more: bit.ly/CechFellows

I am honored to write this award lecture article as a single author, but it reflects the collective effort of our fellows, students, and collaborators. Thank you all for being part of this journey! Lecture video available diabetesjournals.org/diabetes/artic…

Super interesting ! A new UCP1-independent thermogenic mechanism in peroxisomes sciencedirect.com/science/articl…

New! Online now: Aged mice exhibit widespread metabolic changes but preserved major fluxes dlvr.it/TNjkj3

@TVerkerke Highly recommended!!

The Verkerke lab is hiring at all levels. We apply metabolic and bioenergetic techniques to investigate how pathways are rewired in pathophysiology. Experience in bioenergetics,cancer metabolism, metabolomics, molecular biology is a bonus. Email averkerk@umn.edu to apply!

I’m thrilled to share that I’ve started my lab at @UMN_IBP! The lab will study bioenergetic consequences of choline metabolism. I am incredibly grateful to have had amazing mentors in @KajimuraLab @KatsuFunai, thank you!

@TVerkerke @UMN_IBP @KatsuFunai Congratulations!!!! We are so proud of you!!!

The passing Of Dave Mangelsdorf is a terrible loss for his family, friends and the science world. Davo will never be forgotten. 😢 chapelgazette.cfd/david-mangelsd…

@JudithSimcox Congratulations!!!!!

Congratulations to Barbara Kahn for receiving the Roy O. Greep Award for Outstanding research. Nominated by @KajimuraLab.

If you’re at #ENDO2025, Come see our session on NIH/NIDDK 75th year celebration of Adipocyte Biology starting today at 4:30pm. Silvia Corvera, Annabel Wang, JoAnn Manson, Yu-Hua Tseng, Lori Zeltser, and I will be speaking.

@NatMetabolism @Cell_Metabolism @harvardmed @HHMINEWS Thank you!!

#NatMetabPicks | In @Cell_Metabolism led by @KajimuraLab et al. (@HarvardMed, @HHMINEWS) C4orf3 is an ER-anchored protein that promotes calcium cycling independent of UCP1 in adipose tissue. cell.com/cell-metabolis…