Luke Postoak
38 posts

Luke Postoak
@LukePostoak
CRI Irvington fellow in the Murphy lab @wustlmed. Studying dendritic cell biology and cross-presentation.
St Louis, MO Katılım Mart 2022
555 Takip Edilen76 Takipçiler

🧵Excited to share my thesis work out today in @NeuroCellPress from @kipnislab and @TheColonnaLab: "Brain-Engrafted Monocyte-derived Macrophages from Blood and Skull-Bone Marrow Exhibit Distinct Properties." 🧠🦴
sciencedirect.com/science/articl…

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There should be a dedicated journal focused exclusively on publishing confirmed inborn errors of immunity (IEI) cases.
@casanova_lab
Waggoner Lab@LabWaggoner
Structural modeling and functional characterization of a novel gain-of-function TLR8 variant causing severe inflammatory syndrome @JCI_insight @skenterisnt @leibnizLIV insight.jci.org/articles/view/…
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Happy 2026!
@SciImmunology will celebrate its 10th anniversary this year! 🎉 We begin with our Editors’ Choice of articles published in 2025! This free sample collection will be available to read until end of Feb 2026!
bit.ly/SciImm_free
#ScienceImmuno10gy

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I am happy to share our new work on mechanisms of antigen cross-presentation by cDC1. This was a very fun project to work on. A huge thanks to all co-authors for their hard work.
pnas.org/doi/10.1073/pn…
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Ms4a7 expression in cDC1s determines cross-presentation and antitumor immunity
science.org/doi/10.1126/sc… @ScienceMagazine

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We are hiring! Please help spread the words. Thank you!
nature.com/naturecareers/…
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🧵1/
Excited to share my first publication from the @ColonnaLab in @NatImmunol! We investigated how mutations in the human CSF1R gene disrupt microglia and impair white matter integrity in a rare but devastating neurodegeneration called ALSP.
nature.com/articles/s4159…
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Early bird Dendritic cell, Myeloid cell enthusiastic! hurry up Submit your abstract and register soon! poster presentations awards available, amazing talks including: @Idoyaga_Lab @TheColonnaLab @jonykipnis @FGinhoux @KaplanLab @HerbertStr93573 @kodiravi & many others X-less RT

Eynav Klechevsky@klechevskyLab
Langerhans Cells, Dendritic Cell and #skinimmunology lovers❤️ #LC2025 registration is NOW OPEN! Meet us in St. Louis @washu_pathology, Sep. 3-5, 2025, Amazing program! Intimate and collaborative discussions on breakthrough discoveries! register today at langerhans.org
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#Immunology out now @ScienceMagazine
After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen.
buff.ly/lCPsea3
By Jobinet al.

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@Lo_Zanzi @TeamDerave @Cell_Metabolism “Cellular deconstruction of the human skeletal muscle microenvironment”… Huh?
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#WeekendRead. #EveryOrganIsAnImmuneOrgan. @TeamDerave shows @Cell_Metabolism that mast cells release histamine during skeletal muscle exercise which acts on other immune cells, driving an inflammatory program that favors muscle glycogen resynthesis! cell.com/cell-metabolis…
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Luke Postoak retweetledi

#ICYMI Learn about mechanisms that bridge #ImmuneSystem arms in this special collection guest edited by Dr. Sebastian Joyce. It highlights the complex #ImmuneCircuits #ImmuneEcosystems that impact innate & adaptive immunity.
➡️ ow.ly/ZynL50SCpXb
#ReadTheJI #ILCs

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So cool to see our recent publication in @JExpMed from @haldar_lab @pennsurgery @PennMedicine and @MDAndersonNews characterizing a unique population of immunosuppressive iron-rich TAMs highlighted in this month's @ScienceMagazine -
#sec-2" target="_blank" rel="nofollow noopener">science.org/doi/10.1126/sc….
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Luke Postoak retweetledi

Meet the keynote speaker for day one at #CFM_Immunomodulation:
Kenneth Murphy from @WUSTL will speak about 'Development and function of the cDC1'
🤝With the support of @CaixaResearch.
🔗cnio.es/eventos/fronti…

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Congrats @PatFernRod! Distinct lineages contribute to cDC2 diversity: lymphoid-derived pDC-like and myeloid-derived pre-cDC2 both develop into transcriptionally similar cDC2, crucial for humoral immune responses, and are distinct from pro-DC3 derived DC3. twtr.to/Tr5-h
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