Luke Postoak

I wrote this piece to promote thoughtful, respectful, and rational engagement with controversial science topics. I hope it fosters constructive dialogue in the scientific community—thank you for reading and sharing 🙏🏼 @NatRevImmunol nature.com/articles/s4157…

Yale Prof. Akiko Iwasaki writing in Nature: "Our inability to remain open and engage in rational discussions about controversial subjects may be eroding public trust in science." "I remember a colleague whose daughter developed a life-threatening autoimmune encephalitis after receiving the human papillomavirus (HPV) vaccine. I watched her struggle with obstacles in even asking whether her daughter’s illness might be linked to the vaccine. These questions are not only unwelcome in the field but also could jeopardize one’s career and credibility." "The pressure to stay within the consensus view is at an all-time high, for fear of reputational damage, funding exclusion and lack of career promotion, which is amplified at a massive scale on social media. However, there are broader epistemic consequences to staying within the consensus and suppressing alternative viewpoints, which could undermine trust and progress in science." "scientists are unable to freely inquire about the risk of [post-vaccine syndrome] without being labelled as ‘anti-vaxxers’." "True scientific progress depends on a culture that protects dissent"

His feet are light and nimble. He never sleeps. He says that he will never die. He dances in light and in shadow and he is a great favorite. He never sleeps. He is dancing, dancing. He says that he will never die.

@zagrebbi @zoecabina Lmao

Giving a talk soon on open box science + microglia taking the road less traveled. We started with a question about how tissue-resident macrophages develop and ended up uncovering a distinct regulatory program: Maf and Jun drive Zeb2 during primitive hematopoiesis.

If dendritic cells are part of your science, #DC2026 should be part of your year! 🌍Global DC community in San Diego ✳️New biology & discoveries Abstracts & registration are OPEN dc2026sandiego.com ⭐️Come for the science. Stay for the community. @MaxKrummel @ZunigaLab🔁

What a title nature.com/articles/s4146…

@DuSiling @NeuroCellPress @kipnislab @TheColonnaLab Congrats Siling!

🧵Excited to share my thesis work out today in @NeuroCellPress from @kipnislab and @TheColonnaLab: "Brain-Engrafted Monocyte-derived Macrophages from Blood and Skull-Bone Marrow Exhibit Distinct Properties." 🧠🦴 sciencedirect.com/science/articl…

@3DiMMUNE @casanova_lab lol

There should be a dedicated journal focused exclusively on publishing confirmed inborn errors of immunity (IEI) cases. @casanova_lab

Happy 2026! @SciImmunology will celebrate its 10th anniversary this year! 🎉 We begin with our Editors’ Choice of articles published in 2025! This free sample collection will be available to read until end of Feb 2026! bit.ly/SciImm_free #ScienceImmuno10gy

I am happy to share our new work on mechanisms of antigen cross-presentation by cDC1. This was a very fun project to work on. A huge thanks to all co-authors for their hard work. pnas.org/doi/10.1073/pn…

Ms4a7 expression in cDC1s determines cross-presentation and antitumor immunity science.org/doi/10.1126/sc… @ScienceMagazine

We are hiring! Please help spread the words. Thank you! nature.com/naturecareers/…

@DuSiling @ColonnaLab @NatImmunol Congrats Siling!

🧵1/ Excited to share my first publication from the @ColonnaLab in @NatImmunol! We investigated how mutations in the human CSF1R gene disrupt microglia and impair white matter integrity in a rare but devastating neurodegeneration called ALSP. nature.com/articles/s4159…

Early bird Dendritic cell, Myeloid cell enthusiastic! hurry up Submit your abstract and register soon! poster presentations awards available, amazing talks including: @Idoyaga_Lab @TheColonnaLab @jonykipnis @FGinhoux @KaplanLab @HerbertStr93573 @kodiravi & many others X-less RT

#Immunology out now @ScienceMagazine After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen. buff.ly/lCPsea3 By Jobinet al.

@Lo_Zanzi @TeamDerave @Cell_Metabolism “Cellular deconstruction of the human skeletal muscle microenvironment”… Huh?

#WeekendRead. #EveryOrganIsAnImmuneOrgan. @TeamDerave shows @Cell_Metabolism that mast cells release histamine during skeletal muscle exercise which acts on other immune cells, driving an inflammatory program that favors muscle glycogen resynthesis! cell.com/cell-metabolis…

This is a list of blockbuster drugs in 2024. Guess how many can trace their origins to NIH funded research? All of them.

#ICYMI Learn about mechanisms that bridge #ImmuneSystem arms in this special collection guest edited by Dr. Sebastian Joyce. It highlights the complex #ImmuneCircuits #ImmuneEcosystems that impact innate & adaptive immunity. ➡️ ow.ly/ZynL50SCpXb #ReadTheJI #ILCs