Mark Herman

Baylor @bcmhouston and associated institutions awarded grant to establish the Houston #Nutrition and #Obesity #Research Center @MarkHermanMD bcm.edu/news/baylor-aw…

Excited to share our analysis showing that erythritol and erythronate may serve as markers of poor cardiometabolic health and cardiovascular outcomes in older adults. @CBallantyneMD @MarkHermanMD @vijay_nambi @ChiadiNdumele #undfig1" target="_blank" rel="nofollow noopener">sciencedirect.com/science/articl…

excited to share new work Glycerol-3-phosphate activates ChREBP, FGF21 transcription and lipogenesis in Citrin Deficiency led by Vinod Tiwari, Olivia Sun & Edwin Lopez Gonzalez from my lab, Byungchang Jin @russpgoodman lab, @MarkHermanMD & @Cnspracklen biorxiv.org/cgi/content/sh…

Great talk and turnout for Holly Ingraham at the second annual Houston Nutrition and Obesity Research Symposium!

One of the lab's -80 freezers died last night ... samples saved. Happy Halloween! We are in the market for a new one. There were good threads about preferred makes/models in the past but I can't seem to find them. Any recommendations?

Have you ever wondered how mitochondrial and cytosolic pathways for de novo lipogenesis (DNL) interact? We did! Published Online today (cell.com/cell-metabolis…) and led by first-author @adam_rauckhorst, we traced 13C-labeled lactate/pyruvate, acetate, the ketone acetoacetate, and leucine in several mouse models of disrupted hepatic mitochondrial and cytosolic acetyl-CoA generating pathways. Surprisingly, deleting the mitochondria citrate carrier (CiC) increased DNL from both exogeneous and leucine-generated acetoacetate. Overall, our findings delineate a mitochondrial-cytosolic DNL substrate supply network that may guide more accurate therapeutic development for MASLD and T2D. Many thanks to our expert collaborators: No X Ryan Sheldon, now leading metabolomics at the @VAInstitute, who helped start the project and develop the necessary mass spec methods with @adam_rauckhorst; for @StanislawDeja and @Isotopomer for deuterium tracing by NMR and careful contibutions to quantitatively framing our mass spec data; and Tom Vallim of @TarlingVallim for guidance with in vivo gene deletion by AAV CRISPRs. Please also see the exciting co-published manuscript from @WellenLab and Christian Metallo Labs (cell.com/cell-metabolis…) showing that bempadoic acid does more than just inhibit ACLY! @FOEDRC, @UIowaResearch, @UIMolecPhysBio

A substantial reduction of #Alzheimers disease associated with semaglutide (Ozempic) in > 1 million people with Type 2 diabetes from a nationwide data resource alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

Boom ‼️‼️‼️The Houston Chronicle’s Top 100 Restaurant list is out, with 15 making their first appearance and several old favorites topping the list. houstonchronicle.com/projects/2024/…

Among 4,052 adolescents with #obesity who initiated treatment with a GLP1RA, a 33% lower risk of suicidal ideation or attempts after at least 12 months & at up to 3 years of follow-up was observed relative to propensity matched controls @JAMAPediatrics jamanetwork.com/journals/jamap…

We are excited to kick off our series of 4 manuscripts from the RESOLUTE consortium by sharing the metabolic mapping of the Solute Carrier Superfamily (biorxiv.org/content/10.110…)!

Recruiting faculty to the Dept of Molecular and Cellular Biology at Baylor College of Medicine in Houston, TX! Recruiting broadly in cancer and cell biology. Submit by October 1, 2024, for full review. #cellbio @BCMhouston bcm.edu/departments/mo… jobs.sciencecareers.org/job/659987/ten…

New #McNairScholar named at Baylor College of Medicine bcm.edu/news/new-mcnai… @bcmhouston @BCMDeptMedicine #neuromodulation

Your regular reminder of the limitations, pitfalls and controls required for accurate use of and interpretation of data with Cre driver lines in mouse metabolic research @NatMetabolism @WolfrumLab nature.com/articles/s4225…

Dr. Bahar Force discusses clinical advances in the screening, diagnosis, and surgical treatment of patients with Cushing disease. #CME credit available! bit.ly/4fxG4Q6 @bcmhouston @BCMDeptMedicine

The August #DiabetesBio #Podcast is now online! Topics include: Interviews with Drs. Inbal Caspi, @DanweiHuangfu , and @DeepthiPMallela. Sweet talk with coauthors of recent "Classics in Diabetes" Drs. Bernard Thorens and @daveyboyhod. 🎙️ diabetesjournals.org/diabetes/pages… @thewilliamslab @KirkMHabegger @DarleenSandoval

The HuMet Repository: Dynamic metabolomic responses to physiologic tests in healthy adults cell.com/cell-reports/f…

The Whataburger app works as a power outage tracker, handy since the electric company doesn't show a map. Still nearly 1.9 million power outages.

Delighted to receive the Royal Warrant signed by FM & His Majesty the King with my appointment as the Regius Chair of Physiology @aberdeenuni. I would like to thank all my colleagues, friends and lab members over the years! @AberdeenCDC @AbdnLifeScience abdn.ac.uk/news/23324/

Taxing sugar sweetened beverages - helpful? Seattle has some data! #taxes #sugar #obesity #BMI @JAMA_current jamanetwork.com/journals/jaman…

It's happening today! Come meet the Podcast team for #DiabetesBio #DiabetesCare #DiabetesCoreUpdate @AmDiabetesAssn #ADASciSessions