Meredith Gunder, MD, MS
4.1K posts

Meredith Gunder, MD, MS
@MeredithGunder
Surgical Oncologist at @InovaSchar 🦈 by way of @UofLDeptofSurg #CGSO and @TempleSurgery residency 😷🔪💉 @DukeAlumni '13 💙😈🏀 dog mom 🐕


















New 1L HCC Data from China! HEPATORCH Trial (Phase 3): Toripalimab + Bevacizumab vs Sorafenib Median OS: 20.0 vs 15.3 mo | HR 0.76 Median PFS: 5.8 vs 3.7 mo | HR 0.69 ORR: 25.6% vs 5.5% Grade ≥3 AEs: HTN (38%), Proteinuria (19%) Now let's compare With previous data in same space. Cross trial comparison is a SIN in oncology But that's the ONLY sin we all do 😀🙂 @NiuSanford @brunolarvol @OncoAlert @GIcancerDoc @dr_yakupergun @OncBrothers @medicalwatchBC @sujanapriya


🚨 NEOPAN - Pancreatic Cancer Update 🚨 In LAPC (locally advanced pancreatic cancer) 🧬: 📊 Trial compared FOLFIRINOX vs Gemcitabine 👥 171 patients, PS ≤1, unresectable cases 📌 Primary endpoint: PFS 📌 Secondary endpoints: OS, QoL, safety 🧪 Results: 🕒 Median PFS: ➡️ FOLFIRINOX: 9.7 months ➡️ Gemcitabine: 7.7 months 📉 HR = 0.7, P = .04 ✅ 🕒 Median OS: ➡️ FOLFIRINOX: 15.7 months ➡️ Gemcitabine: 15.4 months ⚖️ HR = 1.02, P = .95 ❌ ✅ Better PFS with FOLFIRINOX 🤷♂️ No OS benefit 💊 Well tolerated doi.org/10.1200/JCO-24…









