Motionless I stall 🎻

181 posts

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Motionless I stall 🎻

Motionless I stall 🎻

@MotionlessStall

☕️ Java, Swift, Typescript Dev 🍎 Building iOS and Web apps 🧬 Aging Science

Katılım Ağustos 2022
151 Takip Edilen183 Takipçiler
Motionless I stall 🎻
Motionless I stall 🎻@MotionlessStall·
@statto @KarlPfleger @MartinBJensen @zanehkoch Hmm yeah should've looked at it more closely. 900-day rule is a median lifespan (0.5 survival probability) of 900 days right? So we don't have enough data to know for certain. This would be an interesting experiment to follow up on and replicate
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Zane Koch
Zane Koch@zanehkoch·
for a while i've had a slight fear that the bluetooth from my airpods could be frying my brain this weekend i pulled the raw data from a $30m government study of 1,679 mice blasted with cell phone radiation and reanalyzed it what i found was...not what I expected? 🧵
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Martin Borch Jensen
Martin Borch Jensen@MartinBJensen·
@zanehkoch The untreated controls seem short lived relative to other studies. May be because the boxes and confounding effects are controlled for, but may not be.
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Motionless I stall 🎻
Motionless I stall 🎻@MotionlessStall·
@zanehkoch Mechanical tension is the primary driver of muscle strength and growth. Muscle tears are a byproduct.
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Zane Koch
Zane Koch@zanehkoch·
so why might this be? my guess is its a sort of hormesis effect, where a little of a bad thing ends up being good kind of like exercise: wear and tear on your muscles causes them to grow back bigger and stronger maybe here, the amount of DNA damage and other harms from the radiation is slight enough that is causes cells to upregulate repairs proteins and such, leading to net good effects (side note: we know from a companion study that there really was an increase in DNA damage from the radiation PMID: 31633839)
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Crémieux
Crémieux@cremieuxrecueil·
There are a few people for whom BMI doesn't indicate obesity. Very few. Comparing BMI to body fat-based assessments, there's >98% agreement, with 97% for men and 99.9% for women. BMI works well at the population level!
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Motionless I stall 🎻 retweetledi
Hench D. Kunt🥛
Hench D. Kunt🥛@Chad_Hominem_·
It looks funny but this is actually an excellent way to make basic fitness fun for novices to get in the door. They are definitely burning substantial calories (especially at that weight). We should be encouraging people for this and pushing them to also incorporate resistance training.
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Motionless I stall 🎻
Motionless I stall 🎻@MotionlessStall·
@statto Didn't get everything in here but you can see how the tech layoffs started before / right around GPT-3.5 release
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Andrew Steele
Andrew Steele@statto·
It would be instructive in this debate if this graph were accompanied by a few from other similar-ish industries (high skill, many immigrants, etc). If they show a similar pattern, it wouldn’t *prove* it’s not AI, but it would be a point against. (See QT’d QT for the debate…)
zeynep tufekci@zeynep

I am sold on the power of coding agents — verifiable, formal domain; decades of question/answer databases, etc. But the tech hiring bust is clearly ALSO working off the Covid era hiring bubble plus lack of US visas leading to offshoring. I mean, come on, look at that bump.

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Motionless I stall 🎻
Motionless I stall 🎻@MotionlessStall·
@SeyedMH98 Has it been ruled out that AI coincidentally arrived at a time when these companies would have slowed hiring anyway because because of economic conditions? i.e. is AI just the current excuse to not hire?
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Motionless I stall 🎻
Motionless I stall 🎻@MotionlessStall·
@SeyedMH98 Does AI productivity cause the decline in hiring or does AI spending cause the decline in hiring?
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Raiany Romanni-Klein
Raiany Romanni-Klein@RaianyRomanni·
How could tiny breakthroughs in aging science change U.S. GDP and population growth? What’s the economic value of making 41 the new 40, or 65 the new 60? How many lives could we create or save if we could slow reproductive or brain aging by just 1 year? What would billions of healthier hours be worth to the economy, if we assume no change in the age of retirement? I spent the last two years obsessing over the design, research, and execution of this project. The result is a book upcoming with Harvard University Press, a preprint, and—maybe your favorite part—an interactive simulation tool that lets you input your own timelines and assumptions for specific breakthroughs in aging bio, then see the ROI in terms of US population & GDP growth. From @RickEcon and Jason DeBacker—the economists who co-developed the open-source, macro model that made this project possible—to extensive comments by @tylercowen, @sapinker, Richard Freeman, @NDHendrix, @ebudish, @elidourado, @geochurch, @jasoncrawford as well as interviews with 102 scientists (!) and countless iterations with award-winning designer Giorgia Lupi and the @pentagram team, we built something we hope will be a benchmark for how scientists, economists, designers, philosophers, entrepreneurs and storytellers can come together to paint, fund, and build different flourishing futures for our species. I couldn’t be more excited to share this. It’s the start of an open and evolving project—the labor and product of love, obsession, and unrelenting care. I hope you have fun playing with our simulation tool — and if you do, please share!
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Peter Van Valkenburgh
Peter Van Valkenburgh@valkenburgh·
An unexpected benefit is that you can also put a paper filter on top after tamping and you get improved distribution and flow of water through the puck, less grinds backflowing into the group head, and easier puck removal. Better espresso and experience overall.
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Peter Van Valkenburgh
Peter Van Valkenburgh@valkenburgh·
The reason I got a coronary artery calcium scan. It's because of high LDL and ApoB. My numbers are only mildly elevated and I'm not convinced that those markers are actually atherogenic, but I am leaning on the minority there as far as researchers. Also, interesting to me is the possibility that those numbers are mostly just elevated because of my habit of drinking large quantities of espresso without paper filters, which contains cafestrol. I found 58 mm paper portafilter inserts and will report back in a year.
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Motionless I stall 🎻 retweetledi
Motionless I stall 🎻 retweetledi
Andrew Steele
Andrew Steele@statto·
Just in time for Christmas, here are my top 3 tips for a healthier 2026! Watch this, and more details in the thread below…
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Celine Halioua
Celine Halioua@celinehalioua·
something that has served loyal well: not being emotionally attached to much beyond the ultimate end goal (1st fda-apprvd longevity drug) remote vs IRL, 996, mgmt philosophies etc should be in service of the end goal only & changeable not a core thesis of the company itself
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Andrew Steele
Andrew Steele@statto·
I had a fantastic conversation with @mkaeberlein on the @Optispan_Inc Podcast! We get deep into the social, ethical and economic consequences of aging, and also pretty deep into the science too—I do love nerding out and learning with biologists and doctors. Link below :)
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