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Nutrivore Ch
1.2K posts
Nutrivore Ch
@NutrivoreC
https://t.co/G04stHHaiU Christian Petten L'alimentation ancestrale. Au sommet de la chaîne alimentaire Former SF-operator Nutritionniste agréé ASCA
Katılım Ağustos 2021
545 Takip Edilen54 Takipçiler
@jack_schroder_ @zaidkdahhaj The most ironic part of it all to me is how clearly off balance he is emotionally.
I'd take sub optimal environment and healthy relationships with others / self > perfect environment every single time.
No one that egotistical is at peace in their own mind.
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In some respects, yes
Yet, it’s important to understand that nobody owns the realm of circadian biology. I have learned some cool things from him when I first got into this work years ago, but I have put in the work to place myself as an educator in this space for the rest of my life
80-90% of what I have learned didn’t come from listening to other people. It came from being an autodidact
Some people watch Kruse all day long and try to repeat things elsewhere that he’s said without any study. These people are parrots
Some people suck his dick and never question anything he says. These people are also parrots
Others take it upon themselves to actually study sub-sections/first principles under the larger circadian biology umbrella, which is why I always emphasize to look at somebody’s body of work to see how invested they are
Anybody who gets salty over new characters coming into a space they’ve been focused on for a long time needs to take their head out of their ass for an ego check, including myself
I do not have a monopoly on circadian biology. Kruse does not. Nobody does. That’s the entire point of DECENTRALIZED medicine
What I do personally have is an obsession to learn as much as I can, and that propels me forward to gain a bigger audience, check myself when I’m wrong, refine my message, refine my DELIVERY of that message, and everything in between
We all stand on the shoulders of giants, but let’s not act like those giants are infallible
Let’s not act like they, too, didn’t stand on the shoulders of other giants
Let’s not act like these giants own the space in which they work. They’re simply renting the space for the time that they exist on this planet
Matthew Carroll🧠🔋@SocalMatthew80
@zaidkdahhaj Is it possible that Jack as an early pioneer of circadian biology, who spent years being mocked, and ridiculed by trad medicine now feels more diluted, copied, insufficiently credited with the rise of circadian biology influencers on X? Thoughts @zaidkdahhaj
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If your nose is stuffed, try humming at 130 Hz with your mouth closed.
Google 130 Hz and play the video and then approximate the tune.
If your nose is so stuffed that nothing comes out, open your mouth as little as possible to be able to get a hum out. Hum this way until you can close your mouth.
Then keep humming with your mouth closed.
Stop if your nose gets runny.
The logic here is that you will get a 15-fold increase in local nitric oxide that can loosen up the stuffiness.
Report back here with your results👇
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@exfatloss @reivanen Raw rice is 1,5g lipids per 100g, about 0,6g PUFAs.
If your diet is only rice and about 2000kcal, which is low, you will eat 600g raw rice, and this is at least 3,5g PUFAs and 9g lipides. This is still significant.
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@reivanen I've tried this several times by eating only rice for 30 days. No lasting depletion of this effect size, MAYBE a tiny depletion effect.
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I am extremely skeptical that you could deplete PUFA from all tissues in only 30 days. The people actually attempting this, even literal fruitarians + skim milk, seem to take 4+ years.
Now serum, yea, I've done that in 3 days on a fat-free diet. And SOME tissues turn over rapidly. But all?
It just doesn't match the mechanisms we know are involved or any of the anecdotes. Whatever you do in 30 days is likely a short-term illusion.
@trikomes @TuckerGoodrich @SeedOilDsrspctr
gaezv@gaezpeat
PUFA Depletion Can (probably) Be Accomplished In 30 Days! haidut @BerbarianWizard style diet
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@exfatloss @C02isG00D 3 days for what ? LA depletion or PUFA depletion ?
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@C02isG00D Yea but that's very different than "PUFA depletion can be achieved in 30 days"
By that metric, I can achieve it in 3 days
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@exfatloss @ProjectImpero You have to look not only at LA, but also other n6 and n3 PUFAs. In particular ARA. As far i have seen, this is a point completely ignored by keto/low carb folks. You are just looking at LA levels, but in reductive stress, LA will goes down in favor of ARA.
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I wish Peaters would try & test this stuff more :) Many of us Pufa pilled people have been trying this for years and it seems to take 4+ years.
Serum goes super quick, do a zero fat diet and it'll drop your serum LA within 3 days. I've done it many times.
The trick is, if you go back on a regular/high fat diet, does it come back up? Highly likely yes, cause you didn't deplete much in 30 days, you only masked it within the first 3 days. Serum is not a perfect proxy for adipose for example, it highly depends on your dietary context.
You can test with an OmegaQuant Complete. Unfortunately, almost no Peater seems interested in actually testing that ha.
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Who among us will take the bullet and live off of 6-8 liters of skim milk per day for 30 days?
gaezv@gaezpeat
PUFA Depletion Can (probably) Be Accomplished In 30 Days! haidut @BerbarianWizard style diet
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I might be running my dream company, making life changing cosmetics and Twitter might have opened doors I never thought possible, not to mention giving me purpose in life and contributing to fixing my health, but Georgi Dinkov following me back was still my proudest and most emotional Twitter moment 😭
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@AndrewDBaird1 This study shows "common" retinol concentration in the liver. But i think it's the only one where retinol content of muscle meat from several species was measured with modern methods. and it shows significant retinol content for grassfed animals. Much more than usually excepted
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Retinol in other studies is much lower than the above Darwish study. I've tended to be conservative in my estimates. If retinol was higher in grass fed beef then I think more people might have been okay with beef as only source. Berseem clover/lucerne tend to be much higher than pasture grass, mature forages or stored hay and indeed typical Alberta grasses. Still the beta carotene is low too even with upregulation.
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Low vitamin A myths.
1. Grant Genereux is eating about 30-40 mcgs RAE from grass fed beef or bison when converted from beta carotene to retinol at an enhanced conversion rate. It's not zero.
2. People in my group including me, Jenny Jones and Meredith Arthur are all doing better with moderate Vitamin A and resolving salicylate sensitivity and reducing sulfite toxicity is a bigger help than low Vitamin A. Vitamin A isnt a poison.
3. I've reversed long term problems like gluten intolerance, autonomic problems and short term memory problems by eating moderate Vitamin A in last 3 years. I was always eating one egg a day on low vitamin A in the first 3 years. Some grey hair is turning darker again and I do have light hair at the front where it was bald for 25 years. Moderate Vitamin A may do better at reversing age effects.
4. I eat the RDA for copper or slightly higher. Hair might be getting a bit darker again at age 60. Copper is not toxic.
5. I eat 3 eggs a day and 300 mls of unhomogenised milk each day and am doing better than when on low vitamin A. Hundreds in my group eat 1-2 eggs a day and some drink milk and cheese and are doing better than on low vitamin A. Eggs and dairy are not toxic because of small amounts of vitamin A.
6. There is some need for calcium. Grant Genereux drinks mineral water with calcium in it. Beans have a small amount. Some people eat dairy and green vegetables and do better than when doing low Vitamin A. Dairy is not toxic because of Vitamin A.
7. Bile flow tends to improve with eating eggs (when tolerated). As bile helps remove excess fat then eggs helping store Vitamin A in the liver is only part of the story. Eggs do not cause build up of vitamin A in the liver.
8. There is no evidence that reducing Vitamin A intake increases detox of it. Vitamin A homeostasis is tightly controlled in the brain. There is only evidence of excess Vitamin A being removed from the liver. Vitamin A may be being used for essential functions and lowering intake is very helpful for recovering Vitamin A metabolism. Eating eggs helps liver health. Eggs do not put a halt to excess Vitamin A detox. Vitamin A supplements at 30,000 IUs per day for 4 years never stopped detox of excess. Eggs help Vitamin A metabolism and storage through better liver health, LRAT and bile flow.
9. Retinoic acid is essential for a number of functions like ceruloplasmin, thyroid, mitochondrial energy production, in the liver and the kidneys. The brain tightly controls homeostasis. The body appears to recycyle retinol to plasma 37 times. There are thousands of scientific papers on essentiality of Vitamin A. You can have a vitamin A toxicity and a retinoic acid deficiency at the same time. Grant Genereux may have resolved a retinoic acid deficiency because retinoic acid helps the kidneys. Niacin, choline and protein being very helpful for improving this aspect of Vitamin A metabolism.
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@lowmegatron Co2 dosent come in green bottles and they dont use CO2 they are using O2 oxygen, high CO2 kills cells
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Carbon dioxide heals wounds.
In a trial with people who had chronic diabetic wounds, 2/3 wounds healed with CO2 gas. In the control group, exposed to air instead of CO2, none healed.
The procedure was to wrap the wounded area in plastic, pump out the air, and pump pure CO2 gas into the sealed bag. It lasted 45 minutes per session.
“The results of our research confirmed that transcutaneous application of gaseous COz significantly improved the healing of chronic wounds in diabetic patients. Wounds in study group patients that received CO2 therapy healed significantly faster compared with the control group (Table 2). After CO2 therapy, 66% of the wounds healed completely compared with 0% in the placebo group.”
CO2 is produced in mitochondria during respiration and is often referred to as a waste product of energy production, but its perfusion into tissues has significant health benefits. Blood CO2 is tightly regulated and is not a great indicator here.
The oxidation of glucose under the influence of thyroid hormone T3 is required for optimal mitochondrial CO2 production, affecting rate and quantity. This is why diabetes and hypothyroidism are associated with poor wound healing.
“A substantial body of research links hypothyroidism to impaired wound healing, with one of the most critical mechanisms being disruption of angiogenesis. Angiogenesis is essential during the proliferative phase of wound repair, as it ensures adequate oxygen delivery, nutrient transport, and recruitment of cells required for tissue regeneration. In hypothyroidism, this process is significantly impaired, consistent with the generalized metabolic slowdown seen in the condition.”
CO2 is readily absorbed through the skin, and so the effect of transcutaneous application is similar to that of optimal metabolism.
Ref:
The effect of transcutaneous application of gaseous CO2 on diabetic chronic wound healing-A double-blind randomized clinical trial
Effects of Thyroid Dysfunction on Angiogenesis During Wound Healing and Skin Repair: A Systematic Review
[Image] A Novel System for Transcutaneous Application of Carbon Dioxide Causing an “Artificial Bohr Effect” in the Human Body
Master Metabolism@lowmegatron
Ray Peat and Bud Weiss - The Biology of Carbon Dioxide Better audio, brightened the video. 00:00 Language and altitude, a trip to Russia, Ray’s introduction to science 01:00 J.C. Bose and the properties of life 04:00 Twitching nerves and rocks 05:50 Respiration, Otto Warburg, Albert Szent-Györgyi, William Blake, Swedenborg, brain physiology 07:00 Getting a degree in biology by keeping quiet, membranes 08:30 Gilbert Ling, surface electrical effect 10:00 Science, money, and prestige 11:00 W.F. Koch, respiration, cancer treatments, the quinone system 13:00 Contraction, respiration as electrical property, cardinal adsorbents 14:00 What is CO2? 15:30 Lewis acids, electron donors and acceptors 1700 CO2 as a Koch reagent 18:30 Stabilizing the system, cardinal adsorbents - CO2 and progesterone 19:30 Protein conformation, sodium and potassium 21:00 Hair ion exchange, membrane pumps 22:30 Buteyko, oxygen, and the Bohr curve 23:30 CO2, calcium, and bone density 26:00 Energy at altitude 27:30 Osteopetrosis, marble bone disease 28:30 CO2 baths for cardiovascular disease (watching TV) 29:30 The essentiality of CO2 for all life 30:30 Ideal environmental CO2 levels, planetary temperature 31:00 Low light environments, CO2 and life 32:00 Loss of CO2 with aging, frogs and salamanders 33:30 CO2 protects from poisoning and hypoxia 34:30 The naked mole rat 35:30 Queen bees, lipid peroxidation, polyunsaturated fatty acids, and longevity 36:00 CO2 lowers lipid peroxidation 36:30 Near-death experience, NDE and CO2 37:00 Pure oxygen, medical death, permissive hypercapnia, shrinking the brain 38:30 Stroke, transient ischemic attacks, Coke, baking soda, paralysis 39:50 Curing septic shock and loss of circulation with CO2 41:00 Carbogen, post-war, reductionist medicine 42:15 Hyperbaric oxygen therapy, CO2, water, and cancer 44:00 Absorbing CO2, bones and protein synthesis, bag breathing, and blood pressure 45:00 Bats, caves, longevity and high metabolism 46:00 Dropping a tank of CO2, arthritis 47:30 Breathlessness, Co2 stimulating its production, ETC, cytochrome oxidase, thyroid, altitude, mitochondria 49:30 Diabetes, cancer, lactic acid, NAD, NADH excess, inflammation, cell pH 51:00 CO2, lipolysis, glycolysis, free fatty acids, respiration 52:30 Acid/alkaline, water economy, electrons, gelatin, mechanical hyperventilation 55:00 Altitude, pollution, and asthma 56:00 Did you say you sit in a plastic bag full of CO2?” CO2 springs, membrane gradients 58:30 The Bohr effect 59:00 Carbaminos, pituitary hormones, prolactin, growth hormone, and CO2 1:01:00 So-called receptors 1:02:00 Leaf bag full of CO2 1:03:00 Henderson–Hasselbalch equation, acidifying the system, kidneys 1:04:30 What is the role of bicarbonate in acid/base regulation? 1:05:30 Pregnenolone, progesterone, estrogen, and lactic acid 1:07:00 Thyroid hormone (T3) CO2, respiration, calcium carbonate in bones 1:08:30 Endotoxin, permeability, nitric oxide, TNF, estrogen, suppressing respiration, hypothyroidism 1:10:00 Isn’t estrogen good for the brain? Coke (the other one) is safer 1:12:00 Mae Wan Ho, polarisation streams 1:13:00 The living state, reading a newspaper through a fish 1:14:00 Life as a liquid crystal 1:15:30 CO2 as a context for system models, the limits of reductionist science mp3 link below
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@famedalupo @BerbarianWizard Everything is an oversimplification of the reality
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@BerbarianWizard doesn't take receptor density and distribution into account though
It's part of the story, can be used as a proxy for average population for sure, but it's an oversimplification of the reality.
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I used to store fat mostly in my hips and legs, but now it’s distributed more evenly since I fixed hormonal parameters
Andra@BioavailableNd
Working with thousands of people has trained me to scan for patterns quickly. Fat distribution often acts like a mini hormonal snapshot: - Higher cortisol = more central/abdominal fat - Insulin resistance = more lower abdomen + love handles - Estrogen dominance = more hips, glutes, thighs - Lower thyroid function = more generalized weight gain and puffiness
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@Alexleaf They have more substrats, not free, usable, energy. They usually have less from the latter.
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People with obesity have MORE energy floating around in their blood and accessible to use by other tissues. Insulin resistance of fat cells (caused by lipid overload) literally prevents insulin from effectively locking away their fat, so it just chronically leaks into the blood.
Elie Jarrouge, MD@ElieJarrougeMD
You’re not gaining weight because you “eat too much.” You’re gaining weight because you can’t access the energy you already stored. Imagine a deep freezer packed with food… but the lock is rusted shut. You’d keep buying food. Every day. That’s your body. Body fat = deep freezer Insulin resistance = rusted lock Low carb. Fasting. Strength training. Good sleep. That’s how you break the lock and open the deep freezer.
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Been eating about 500 mg of natural vitamin C for last 2 weeks and feel better than before doing that
Bioenergetic Brain@BioenergeticBrn
Albert Szent-Gyorgyi on malnutrition
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@metabolic_print Also reread Peat books again every few months or so, he was very well-informed in fields beyond basic nutrition and endocrinology
I've read GE and MM each like 3-5 times now and I learn more each time
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Any book recommendations? Finished the main Ray Peat books
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Sugar doesn’t tank your testosterone. chronic hyperglycemia does.
there’s a difference and almost nobody in this space makes it.
Ray Peat was saying this decades ago and got dismissed by the same people now selling low carb testosterone protocols.
Acute glucose availability is required for steroidogenesis. Your Leydig cells run on cellular energy. starve them and testosterone synthesis slows regardless of what your total T looks like on paper.
The problem was never carbohydrates, it’s dysregulated insulin, mitochondrial dysfunction, and the chronic inflammatory state that follows years of processed food and seed oils.
A man eating fruit, root vegetables, and whole starches is not in the same conversation as a man eating refined sugar and vegetable oil all day.
Peat understood that the cell needs fuel to make hormones, not macronutrient restriction, not intermittent fasting. actual oxidative energy.
Fear of carbs tanked more hormones than carbs ever did.
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@MichaelLexner @anabology Yea you def have to get used to it. Took me a few weeks.
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@Fowler_Fitness1 Let this poor estrogen dominated old man in peace please
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Kruse is the quintessential definition of the supposed “pseudo-intellectuals” he criticizes. He always shifts the supposed “causal agent” of a disease away from a well-accepted narrative or popular point of view to fit whatever his preferred new “flavor of the month” micro spin-off theory (usually of DD, light, or magnetism) happens to be at the time
This couldn’t be more clear with all of the nonsense he’s been running through ChatGPT lately trying to implicate deuterium in everything.
Just because “everything is connected (I.e you can find a casual relationship (or even create some far fetched, completely hypothetical mechanistic one) doesn’t mean it’s relevant.
That is why the Texas-to-California fart analogy that I’ve used many times lands so well with people. Yea, the atmosphere is obviously continuous (and everything is biology is “connected) yet if I cut one💩 in Austin you will never smell it in Los Angeles. The “connection” is real, but the signal is far too weak by the time it drifts west.
All of this deuterium nonsense is an attempt to filter key talking points from other health and wellness influencers through jack’s preferred paradigm. Mainly in an attempt to convince people he has something figured that other people don’t.
It’s an ego thing, guys. Can we not see this yet? Every neurosurgeon is this way
When people finally started aligning with this general ideas and sentiments about light, he had to make his position on it even more arcane, obscure and convoluted.
There’s always something deeper that other people apparently don’t know that only he does.
The story constantly changes and becomes more ridiculous over time. That’s how gurus keep you hooked, waiting for the next “paradigm shifting” piece of information to drop
Most of this is just intellectual status-signaling. A sad ttempt to gain prestige by appearing to operate at nore fundamental or "esoteric" level o understanding ("everyone’s wrong — except for me!") regardless of the context's actual requirements.
Just because you can draw a line between two points doesn't mean that line carries any weight in the real world.
The "first principles" label is often used as a shield for over-reductionism. People strip a problem down to its atoms, ignore the messy reality of how those atoms actually behave together (emergent properties), and then build a "logical" tower that’s totally disconnected from reality.
☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆@DrJackKruse
Another bacteria that does well in deuterium........Deuterium, not the bug is the cause of the cancer. Deplete the deuterium the can goes bye bye. Read the book because this guy won't. He just posts crap because he has no biophysical framework to draw upon.
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@lowmegatron "Vitamin A deficiency is thus associated with increased TSH secretion" -> that would stimulate increased T4/T3 secretion by the gland, isn't?
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Vitamin A deficiency causes:
> Thyroid enlargement
> Increased TSH
> Decreased iodine uptake
> Decreased thyroid hormone synthesis
> Decreased thyroid hormone conversion
“The metabolism of vitamin A seems fairly closely connected to the activity of the hypothalamic-pituitary-thyroid axis. Animal studies show that vitamin A deficiency is associated with decreased thyroid iodine uptake, limited synthesis and secretion of hormones, as well as thyroid enlargement. The total serum triiodothyronine and thyroxine concentrations increase (common transport proteins e.g. transthyretin bind both thyroid hormones and the retinol-binding protein, the synthesis of which decreases in vitamin A deficiency). The rate of hepatic conversion of thyroxine to triiodothyronine is also decreased. Normally, the secretion of thyroid-stimulating hormone (TSH) is regulated by the thyroid-hormone-activated receptor and the retinoid X receptor. The latter, after binding the ligand (vitamin A) binds with its promoter region of DNA encoding the beta-subunit of TSH, limiting its expression. Vitamin A deficiency is thus associated with increased TSH secretion [18].”
[The role of vitamins in the prevention and treatment of thyroid disorders]
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S-Tier OmegaQuant Complete. One of the most impressive results I've ever seen.
Linoleic acid: 7.7%, which takes years of avoiding seed oils to achieve.
Omega-6:Omega-3 ratio is 1.1:1, which is just insanely low.
Omega-3: 17.93% (!)
All that on a low-fat but not nearly zero-fat diet, which you can tell by the levels of palmitoleic and oleic acid.
GatorDadSteve@gatordadsteve
My buddy @exfatloss wanted me to do a QOC.. here we go!
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