Priyanka Singh

971 posts

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Priyanka Singh

Priyanka Singh

@PS_lab

Associate Prof. @iitj, INYAS, DBT-IYBA, AvH Fellow, EMBO-LTF | Alumni:@wwu-muenster @mpidortmund @biozentum | Cell division, Centrosome, Microtubules & Cilia

Jodhpur, India Katılım Mayıs 2018
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Priyanka Singh
Priyanka Singh@PS_lab·
Honoured to receive the prestigious “Har Govind Khorana-IYBA 2019” @DBTIndia @IITJ_Official . Life lesson i learnt after giving birth to my baby boy and presenting my proposal for award in next 72 hrs is that motherhood makes you stronger. Dear Son..this ☝️ is for you. 💕Mom
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Priyanka Singh
Priyanka Singh@PS_lab·
Thrilled to share that another patent has officially been granted! 🚀 Proud of the team, and the journey it took to get here.
Thankful to @SM_IITJ for the collaboration—this work opened up new perspectives around our research theme.#microtubules #cancer
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Abhinav
Abhinav@Gayakwad72087·
@PS_lab @SM_IITJ This is truly a magnificent achievement! Many congratulations to you and your entire team. 🎉
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Nagaraj Balasubramanian
Nagaraj Balasubramanian@AdhesionLab·
"KIF5B and Dynein-Dependent Golgi Organization: Role in Adhesion-Dependent Microtubule Acetylation." Out this week, work led by @AntaraC9 from the lab in @TrafficJournal. Work supported by @IISERPune and @ANRFIndia @serbonline In control cells, active Arf1 facilitates the recruitment of KIF5B and dynein to the Golgi, maintaining its juxtanuclear organization. KD of either KIF5B (KIF5B KD) or dynein (DYN KD) disrupts Golgi organization, forming Golgi ministacks, with cis- and trans-Golgi localizing together. In KIF5B KD cells, active Arf1 could recruit dynein to ministacks, positioning them near the MT-organizing center (MTOC). In DYN KD cells, MTOC is localized close to the plasma membrane. This, combined with active Arf1-recruited KIF5B, causes the dispersal of ministacks. In cells with joint KD of both motors (DUAL KD), the Golgi becomes compact around the MTOC, keeping their relative cis- and trans-Golgi localization. This Golgi remains MT-associated and supports MT acetylation, similar to control cells. So it's different but similar, and could be a tool for understanding how motor proteins regulate Golgi organisation. The question that remains to be answered is: how 'normal' and, hence, a 'control' is John ! 🙂
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Nagaraj Balasubramanian@AdhesionLab

Four is indeed better than one......coming soon. #Golgi #Beatles: an analogy many years in the making!

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GhoshRoyLab
GhoshRoyLab@GhoshRoyLab·
It is our pleasure to see our article on the cover of @SfNJournals. Great cover art and project by @windowofnature. A new direction in the lab linking physical exercise to nerve regeneration. @DBT_NBRC @DBTIndia @India_Alliance. Original article: jneurosci.org/content/46/9/e…
SfN Journals@SfNJournals

This Week in The Journal #JNeurosci | A Brain Marker for Higher Intelligence in Children; A Subcortical Hub for Naming Objects jneurosci.org/content/46/9/e…

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Nagaraj Balasubramanian
Nagaraj Balasubramanian@AdhesionLab·
Congrats @ArnavSaha19 and @Tush96rkhane !! Thanks for the support @ANRFIndia and @IISERPune. Also, thanks @J_Cell_Sci for featuring this study as the cover for this issue. The 'Research Highlights' for the study & First Person reports were an added bonus. Check the links below.
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J Cell Science@J_Cell_Sci

Arnav Saha @ArnavSaha19, Tushar Sherkhane @Tush96rkhane & Nagaraj Balasubramanian @AdhesionLab @IISERPune uncover a mechanosensitive pathway linking ECM stiffness to Golgi organisation & function in breast cancer cells. journals.biologists.com/jcs/article/13… Article: journals.biologists.com/jcs/article/13…

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