Phil Strandwitz

WATCH | @RepLaHood questions biotech leaders on how China is cornering the medicine market and what it means for patients and national security. "China’s rapid advancements in biotechnology are challenging America’s leadership. We must ensure life-saving innovation starts and stays here in the U.S., for the sake of patients and national security."

WATCH | @StrandTx's Dr. Jacob Becraft warns, "a future where we hand control to China over the discovery, development and manufacturing of the medicines we rely on is truly not far away.” The race for clinical data is the race for global leadership.

creating a groupchat for biotechies, humans-only, independent projects encouraged drop your fav bio-meme below to get added

@kulesatony I have always thought that if we could reduce the friction of exposing society to it's problems and/or unknowns, give those curious the tool kit(s) to tinker, and a coordinated means to contribute, that same Minecraft/RPG grind energy could be funneled towards such innovation.

Very important questions in this essay.

Love these "Visions of the Future" posters from the Jet Propulsion Laboratory of @NASA . I'm thinking we need something similar for what our microbial future will be. jpl.nasa.gov/galleries/visi…

I'm ready for this! Can't wait to participate in my first SynBioBeta and share how we're using our microbiology-first platform to map the gut-brain-axis. If the pre-conference call (with around 150 attendees) is an indication of the energy of the event, it's going to be a blast!

2) We ended up not using it, because we thought it was too awful. I challenge everyone here to try to make a decent hippocorn image. It's basically impossible to make a good one.

Generative AI -- hype or the real deal? Now or in 5 years? I thought I'd do a super deep dive on this over the holidays by becoming a cartoonist. Plus: what AI company would I start based on these findings? Read on >>

@JTRobinsonLab @motifneuro Awesome - well done Jacob!

Can’t wait to take the next step with @motifneuro! This funding will allow us to launch the first clinical trial with magnetoelectric-powered implants - a new architecture for neuromodulation. Credit to team at Motif and the supportive environment at Rice and the Launchpad!

@ugizashinje @bryan_johnson I lead a biotech that does a lot of translational microbiome research. One of our projects includes isolating and growing communities of microbes from people + mapping what foods/ingredients they interact with. Currently can't this level of resolution with sequencing data alone.

@PhilStrandwitz @bryan_johnson That sounds interestig, but how do you that ?

Short-chain fatty acids (SCFAs (microbiome)) may decrease with age, including butyrate, propionate, and acetate. Higher levels of SCFAs may have whole-body benefits; however, this is unclear in the context of caloric restriction optional nutrition (CRON). We've been trying to increase my SCFAs and have yet to succeed. Test results: gdx.net/products/gi-ef… We're aiming for the following levels: SCFAs total: 50 micromol/g n-Butyrate Concentration: 10 micromol/g Any suggestions?

@titanioustom And it's probably not just equity in many of these cases - in the Oxford Nanoimaging deal it was 50% equity (!) and 3.5-6% of net sales on a sliding scale.

If the goal is to foster and incentivize the creation of companies around novel science and technology then I'm not sure this structure nor this attitude towards negotiation is the right way

This is a great piece about the startup environment in the UK and the duality in perspective of founder versus TTO: sifted.eu/articles/oxfor…

Super excited to see this published --> a pilot placebo-controlled FMT trial for depression, the first of its kind. What a beast of a study to get done during a pandemic. Sets us up well for a powered trial (first link = protocol; results = linked at the end of the thread).

@jmigueljd @J_LHeureux23 @BCMSpaceHealth @DARPA @DoritPhD Way to go Miguel! Super cool

We found probiotics are mostly dead! biorxiv.org/content/10.110… Instead we (@J_LHeureux23) made synthetic extremophiles that survive heat solvents & more They could treat diseases better, grow crops more sustainably & even help get us to mars @BCMSpaceHealth @DARPA @DoritPhD

@gilbertjacka "Probably perfection"

Honest opinion: Too much or just right?

When passions for poop science and writing intersect - a great read from @StephenSkolnick, one of my favorite Holobionts.

The microbiome field has been watching -- great to see a positive vote for both safety + efficacy from the FDA's AdCom meeting for RBX2660 (Rebyota). Big congrats to @Rebiotix. A significant milestone + just the start of the incredible potential in manipulating our microbes

@titanioustom @MichaelRetchin @JocelynnPearl Gets me every time.

@MichaelRetchin @JocelynnPearl I actually opened it to see if there was a follow up

people of twitter, I know this is shocking. But we do not need another list of things you learned.

Things I wish I had access to when launching Holobiome as a first-time founder...this

@kulesatony Let's go!

There is an insanely exciting revolution underway in how we fund and organize science. Crazy to think what it will be like to look back on this period 50 years from now.

Incredible. First thought was it looks like a darkfield microscopy shot of any microbial community (like poop or soil). Unexplored galaxies everywhere we look.