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Rui Sousa-Luís
33 posts
Rui Sousa-Luís
@RSousaLuis
PhD student @IMMolecular + RA @Dunn_School | Transcription & RNA processing
Katılım Kasım 2019
147 Takip Edilen71 Takipçiler
Rui Sousa-Luís retweetledi
Very happy to see this out at @GeccoConf 🙌 We used evolutionary algorithms constrained with domain-specific grammars to generate synthetic sequences covering the biological space predicted by deep learning models in genomics. Paper: dl.acm.org/doi/10.1145/36… #genomics
Alcides Fonseca@alcides
📢New paper alert! In "Semantically Rich Local Dataset Generation for Explainable AI in Genomics" @GeccoConf, @Pedro_Barbosa3 proposes an evolutionary approach to generate sequence-based local datasets to understand genomic variation prediction tools (like SpliceAI).
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Check out our latest pre-print on voyAGEr, a web app that leverages GTEx transcriptomic data to support researchers with no bioinformatics expertise in the analysis of age-related gene expression alterations in human tissues:
doi.org/10.1101/2022.1…
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Rui Sousa-Luís retweetledi
Rui Sousa-Luís retweetledi
Happy to share the work I have been developing at @IMMolecular and @scerg_ibb 😊
90 Segundos de Ciência@90segundosPT
Teresa Silva do @IMMolecular está a desenvolver organóides de cerebelo, versões simplificadas de órgãos in vitro, para estudar a doença Niemann-Pick do tipo C, uma doença rara que leva ao desenvolvimento de problemas neurológicos. buff.ly/3P8A6rO #90SegundosCiência
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Rui Sousa-Luís retweetledi
DeepSTARR predicts enhancer activity from DNA sequence and enables the de novo design of synthetic enhancers (de Almeida et al.) ow.ly/8KvA50J6vPE @deAlmeida_BP @reiterfanny @AlexanderStark8
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Rui Sousa-Luís retweetledi
I am so happy 💙 to see Idalio Viegas’ PhD work published today. It is a story about #RNA modifications in poly(A) tails, but also about a broken arm and revision during lock down. Thanks to @FundlaCaixa @HHMINEWS and @EMBO_YIP. @parasitesrule nature.com/articles/s4158…
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Rui Sousa-Luís retweetledi
here it is... finally out :) "Transcription and splicing dynamics during early Drosophila development" pubmed.ncbi.nlm.nih.gov/34667107/
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Rui Sousa-Luís retweetledi
We are recruiting! @wellcometrust funded postdoc position available in my lab @BabrahamInst to work on B cells and antibody gene diversification. Please RT
Babraham Institute@BabrahamInst
VACANCY: One week left to apply! We are seeking to recruit a Postdoctoral Research Scientist to study the molecular and cellular mechanisms regulating antibody gene diversification in B lymphocytes Full details: babrahaminstitute.livevacancies.co.uk/#/job/details/… #ScienceJobs #PostdocJobs #Immunology
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Rui Sousa-Luís retweetledi
How do cell populations in the human liver respond to regeneration? @ABgnieska, me and more @TreutleinLab @GrayCampLab used scRNA-seq to find out - our new preprint out now!
🧵⬇️
twitter.com/biorxivpreprin…
bioRxiv@biorxivpreprint
Cell atlas of the regenerating human liver after portal vein embolization biorxiv.org/cgi/content/sh… #bioRxiv
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Nice talk by Rui Sousa-Luís!😊
#RNA2021 #RNA
POINT technology illuminates the processing of polymerase-associated intact nascent transcripts cell.com/molecular-cell…
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Enjoyed the Alternative Splicing Session today #RNA2021. Great talk by @RSousaLuis (C15-2) covering his POINT-tech @MolecularCell paper using long-read POINT-nano sequencing to look at intact nascent RNA splicing kinetics from Pol II-associated transcripts. Nice! @nanopore #cDNA
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Rui Sousa-Luís retweetledi
Interesting paper about an innovative technology #POINT to decipher the speech of our cells, unveiling the complex journey of #RNA.
@RSousaLuis @MCarmoFonseca @Taka_Nojima & Nick Proudfoot @MolecularCell ➡️ bit.ly/3oPHmM9
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Rui Sousa-Luís retweetledi
Researchers have developed a new technology to capture and characterize newly transcribed, or nascent, #RNA. @Taka_Nojima @MolecularCell
ow.ly/cZKU50E3zys
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Rui Sousa-Luís retweetledi
Our research article spearheaded by
@WolfgangKopp3 on #deeplearning for #genomics is listed as one of the top50 articles of 2020 in @NatureComms (nature.com/ncomms/top50). The article is here: nature.com/articles/s4146… #NCOMTop50
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@RSousaLuis @MolecularCell @MCarmoFonseca @Taka_Nojima Uauuu! Muitos parabéns!! Primeiro de muitos 😜
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So excited to share my first ever publication as 1º author @MolecularCell!! 🌟🥳It has been amazing this collaboration between @MCarmoFonseca @Taka_Nojima and Nick Proudfoot labs! Check out our POINT technology paper, where we shed light on the nascent RNA world 🔎
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Rui Sousa-Luís retweetledi
The @JCellBiol article about Taka’s Covid job search is here
rupress.org/jcb/article/22…
Taka Nojima@pol2rna
Very happy to share my experinece (or story?) of job hunt during this COVID19 pandemic @JCellBiol Hope this helps young people to have some idea on PI interview process. Also I thank my supervisor Nick Proudfoot @Dunn_School for great days to incubate me to be a PI.
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Rui Sousa-Luís retweetledi
POINT technology illuminates the processing of polymerase-associated intact nascent transcripts: Molecular Cell cell.com/molecular-cell…
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@RSousaLuis @MolecularCell @MCarmoFonseca @Taka_Nojima Not a bad place to have your first 1 author paper 💪🏼 congrats!
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