Russell Siebert

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Russell Siebert

Russell Siebert

@RussellSiebert

Committed husband & father, tenured healthcare tech leader, real estate, crypto, multiple streams, health/wellness, racing cars, whiskey

Dallas, TX Katılım Şubat 2012
516 Takip Edilen263 Takipçiler
Camus
Camus@newstart_2024·
Andrew Santino just blew my mind with one simple comparison. A million seconds = 11 days. A billion seconds = 31 years. Let that sink in. We throw around “billionaire” like it’s just “millionaire but with more zeros,” but the actual gap is insane. A million seconds is less than two weeks. A billion seconds is longer than most people’s entire adult lives. It’s a perfect reminder of how detached our brains are from what these numbers actually mean. Next time someone casually says “he’s a billionaire,” just remember: that’s not “a lot of millions.” That’s an entirely different universe of scale. Mind officially blown.
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Russell Siebert
Russell Siebert@RussellSiebert·
@themoviedadsc Was literally 90 SECONDS today at 4 pm, terminal D, DFW TSA precheck and there was no wait for non-precheck either.
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Sean Cranston
Sean Cranston@themoviedadsc·
Kinda surprised that the overwhelming consensus is that airport (TSA) wait times have been overblown, and it hasn't really been that bad for most flyers (according to comments in my original post).
Sean Cranston@themoviedadsc

Legitimately now considering driving 14.5 hours to Ft. Lauderdale this coming weekend vs. flying. Drive is brutal, but my worst nightmare is getting caught in this TSA mess flying with 3 young kids Question to those who've been flying. Is it really that bad right now?

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Oscar Chalupsky
Oscar Chalupsky@OscarChalupsky·
Tough news yesterday. I’ll need 30 radiation sessions to keep the skin cancer under control. With all the chemo for my Multiple Myeloma, my resistance is very low. Right ear still deaf and my arse still painful,but I still got out for a walk. Some days you don’t win
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Russell Siebert
Russell Siebert@RussellSiebert·
@shteivred Funny. First day of college stats the professor’s statement to the entire class…”Lies, damn lies and statistics. You can make data say whatever you want…”.
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Russell Siebert
Russell Siebert@RussellSiebert·
Statins are literally one of WORST drugs ever developed. You will end up absolutely wreaked later in life. Educate yourself on absolute vs relative risks and benefits. Pharma companies use these stat ‘tools’ to tell the narrative they want. The actual results are that you MAY live 4 DAYS longer with a statin but with massive additional risks including Alzheimer, dementia and diabetes. Contrary to common belief the longest living people tend to have HIGH cholesterol….take a guess as to what your brain is predominantly made of….taking a drug to suppress lacks common sense.
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Crémieux
Crémieux@cremieuxrecueil·
This is good! More people should be on statins. They are basically a wonder-drug. They have very few side effects and almost no serious ones, and they deliver huge reductions in cardiovascular risk and extension in lifespans, for $2 to $10 per month.
Crémieux tweet media
Crémieux@cremieuxrecueil

Note: I am referring to a real thing. Early use of simvastatin comes with considerable life extension: x.com/cremieuxrecuei… And meager weight gain: x.com/cremieuxrecuei…

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Russell Siebert
Russell Siebert@RussellSiebert·
@drterrysimpson The only problem, multiple researchers are on record, under oath stating that they have tested the vaccines and found DNA massively higher than FDA approved levels.
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Dr Terry Simpson
Dr Terry Simpson@drterrysimpson·
You’re mixing theoretical molecular biology with what actually exists in the vaccine. Yes — SV40 promoters can drive transcription if they are integrated upstream of a gene. But that requires DNA integration into the genome, which is the step you are simply assuming. The COVID mRNA vaccines contain modified mRNA, not DNA capable of replication. The tiny fragments of plasmid DNA occasionally detected during manufacturing are non-replicating and degraded quickly in cells. For them to affect gene transcription you would need: Entry of intact DNA into the nucleus Double-strand breaks in genomic DNA Integration at the correct orientation near a gene Persistence in enough cells to matter biologically That chain of events is extraordinarily unlikely and has not been demonstrated in vivo with these vaccines. The gene-therapy studies you’re referencing prove the opposite point: they require engineered systems specifically designed to force integration—usually CRISPR, recombinases, or targeted nucleases. Without those tools, LNP-delivered nucleic acids overwhelmingly remain episomal and transient. And after billions of doses worldwide, we have no signal of insertional mutagenesis, cancer spikes, or any clinical pattern suggesting genomic integration. So yes—molecular biology allows many things in theory. But regulatory decisions are based on evidence, not speculative chains of improbability. Promoters regulate genes only if they integrate. There is no evidence that vaccine mRNA or residual plasmid fragments integrate into the human genome.
Charlotte Kuperwasser, PhD@KUPERWASSERLAB

You are correct that the SV40 promoter is not a gene. However, it is incorrect to say that it cannot affect gene transcription. The SV40 promoter is one of the most potent viral promoter/enhancer elements used in molecular biology and is routinely employed to drive high levels of gene expression in mammalian cells. That is precisely why it is used in all sorts of applications. If such a promoter were integrated into the genome, particularly upstream of a gene, it could easily influence transcriptional activity. This is a well-established property of strong viral promoter/enhancer elements. And DNA integration does not require more than reverse transcription. Integration of exogenous DNA (especially linearized DNA fragments) can occur through normal DNA damage repair pathways (eg. NHEJ), particularly in the presence of double-strand breaks (DSB). These breaks arise routinely during DNA replication and can also be induced by cellular stress, inflammation, or oxidative damage. Laboratory experiments have quantified integration to be ~1-10% of cells when DNA is encapsulated in LNPs. LNP-delivered DNA is the bedrock for transgene expression after integration. This is actually the basis for gene-therapy that is used in people. Measurable integration has been demonstrated in vivo when the system is explicitly designed to create or exploit DNA breaks (i.e., genome editing contexts). For example, there are in vivo LNP-enabled DNA knock-in studies where integration is a goal and is driven by genome editing/repair processes rather than “spontaneous” integration of plasmid DNA in the absence of targeted breaks. The key scientific issue is therefore not whether integration is theoretically possible as the molecular mechanisms for it are well established. But whether it occurs from the byproducts found in the vaccines and, if so, at what frequency. We do not know the fate of the DNA present in the vaccines. No safety data has been provided on LNP-encapsulated DNA . Not having data on this 6 years after deploying the technology in people is a regulatory failure.

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Russell Siebert
Russell Siebert@RussellSiebert·
@Jasper_Truth You are a soul in a meat sleeve…God’s child. Plan and act accordingly.
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Jasper Truth 🇺🇸 🇨🇦
Jasper Truth 🇺🇸 🇨🇦@Jasper_Truth·
YOU ARE NOT YOUR NAME, YOUR JOB, YOUR BELONGINGS, YOUR FAMILY, YOUR HOBBIES, OR YOUR BODY. SO WHO ARE YOU? Lee Harris ~ Remember Who You Are - Lee Harris Channeled Message (Initiation Broadcast 1)
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Russell Siebert
Russell Siebert@RussellSiebert·
@dgt10011 Via Jane Street most likely! Isn’t there a connection to your firm there?
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Jeff Park
Jeff Park@dgt10011·
TREASURY EXPECTED TO ANNOUNCE MEASURE AS SOON AS THURSDAY TO COMBAT RISING ENERGY PRICES THAT INCLUDES USING OIL FUTURES MARKET - SENIOR WHITE HOUSE OFFICIAL Crude curve control (CCC) incoming
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Russell Siebert
Russell Siebert@RussellSiebert·
Not this. Unless you can solve for federal and state level regs out of the box (eg, HIPAA, PHI, PII, SOCII, HITRUST), just to get started. The learning curve is extremely steep and there are thousands of companies already in the space. Not saying don’t do it if you have a killer idea, it’s simply not easy.
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Barrett Linburg
Barrett Linburg@DallasAptGP·
Chris Koerner@mhp_guy

I just spend a week at a Mexican resort with 150 doctors. And wow. I can now say with 100% certainty that I know what the biggest wealth creation opportunity of 2026 is. These guys are the best of the best, each making $500k - $5m+ per year. I gave a keynote about how to implement AI into their practices, and what I learned kind of shocked me. I asked how many knew what an AI wrapper was. MAYBE 2 hands halfheartedly went up. Vibe coding? Crickets. Replit? Nope. How many have ever uploaded a file to AI? Maybe 20% of people. I couldn't even get through my 2 hour talk because they were asking so many questions. These guys were almost all 35-55 year old wealthy Americans, on the cutting edge in their field. I don't care what size the business is - small, large, medium, it doesn't matter - business owners are DESPERATE for someone to do 3 things for them with AI. 1. Solve problems. 2. Save money. 3. Make money. So what's the opportunity? Get in front of them for free. Any way you can. In your local area, preferably. Rent a freakin' Holliday Inn conference room for an hour if you have to. Promote the event with the FB ads + Eventbrite integration. Have your buddy sign them up for a demo in the back of the room. You will have 5 figures in monthly recurring revenue in a matter of days, not months. You don't have to do an event, but the close rate is stupid. I know of at least 10 people doing this today. X is a bubble. The stuff you see here about OpenClaw, AI wrappers, Claude's capabilities, etc, is all 2-3 years ahead of the general public.

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Sean Sweeney
Sean Sweeney@seandsweeney·
Need help. One of my newsletter readers (young aspiring real estate developer) hit me up with a question I can't answer. "While it's tough to develop, should I be looking to build something on AI/Claude? $5-10k/month passively would change my life right now." What say you?
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Russell Siebert
Russell Siebert@RussellSiebert·
Not surprised by this. Curious how many of these MDs are in private practice vs working for a system. I’d guess that most are private. This is my industry (30 yrs healthcare tech). Not to dissuade any followers, just know that every PE/VC firm is backing multiple companies in this space. AI is coming fast at health care, and many MDs are already using ambient AI to listen to patient visits, create the clinical note and start the billing process. There is enormous opportunity in the space, just know there are literally thousands of companies already here. My recommendation is if you have AI chops, maybe investigate working for a current player to learn the market. The learning curve is extremely steep and the regulations are large and expensive to manage. I will also share, there are hundreds if not thousands of 3rd party billing companies, many of whom use off labor arbitrage. Most of these firms can’t spell AI. If they don’t embrace it now, they will literally cease to exist in 5 years…..those companies need help fast.
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Chris Koerner
Chris Koerner@mhp_guy·
I just spend a week at a Mexican resort with 150 doctors. And wow. I can now say with 100% certainty that I know what the biggest wealth creation opportunity of 2026 is. These guys are the best of the best, each making $500k - $5m+ per year. I gave a keynote about how to implement AI into their practices, and what I learned kind of shocked me. I asked how many knew what an AI wrapper was. MAYBE 2 hands halfheartedly went up. Vibe coding? Crickets. Replit? Nope. How many have ever uploaded a file to AI? Maybe 20% of people. I couldn't even get through my 2 hour talk because they were asking so many questions. These guys were almost all 35-55 year old wealthy Americans, on the cutting edge in their field. I don't care what size the business is - small, large, medium, it doesn't matter - business owners are DESPERATE for someone to do 3 things for them with AI. 1. Solve problems. 2. Save money. 3. Make money. So what's the opportunity? Get in front of them for free. Any way you can. In your local area, preferably. Rent a freakin' Holliday Inn conference room for an hour if you have to. Promote the event with the FB ads + Eventbrite integration. Have your buddy sign them up for a demo in the back of the room. You will have 5 figures in monthly recurring revenue in a matter of days, not months. You don't have to do an event, but the close rate is stupid. I know of at least 10 people doing this today. X is a bubble. The stuff you see here about OpenClaw, AI wrappers, Claude's capabilities, etc, is all 2-3 years ahead of the general public.
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Russell Siebert
Russell Siebert@RussellSiebert·
@1914ad Wow! Fascinating read, thanks for sharing. What an incredibly criminal company.
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Justin Bechler #BIP-110
Justin Bechler #BIP-110@1914ad·
Bryce’s Secret is bigger than The Big Short. A summer intern, a private Telegram channel, a reclusive billionaire who funded an African coup. A swap that destroyed $40B. Suicide hotlines pinned to Reddit, a wallet that’s been dark for years and a lawsuit that names everyone.
Justin Bechler #BIP-110@1914ad

x.com/i/article/2027…

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Flex Futures
Flex Futures@FlexFutures00·
@9mmsmg Where are we buying this at ? Any reliable sites ? See lots of people discussing it but no info on obtaining
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9mmSMG
9mmSMG@9mmsmg·
I took everyone's suggestions about the proper titration schedule for Retatrutide under careful consideration and totally ignored them. People were saying to start at .5mg or 1mg, but I started at 2mg, the same as the studies did. The goal is to reach the effective dose of glucagon, so im not going to waste time and cry about a tummy ache if I get one. Weeks 1-4 2mg Then 4mg and then 6mg If all goes according to plan.
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Maria
Maria@mariaart55·
This morning, we cradled our daughter as she took her final breath. Sasha lay in our arms, weary from a battle no child should ever have to fight. Cancer stole her strength, but it could never dim her light. In her final moments, there was peace in her eyes and love in every breath she drew. She left this world the same way she lived—wrapped in love, held close, just as she whispered, “Hold me tight.” Though she is no longer in our arms, she will live forever in our hearts.
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Russell Siebert
Russell Siebert@RussellSiebert·
Hey @AnthropicAI my 11th grade HS son is taking calc B/C and was struggling with a home work problem. I suggested he try the latest 4.6. ….. this was the result. What up?! Sonnet can’t do high school calculus?!
Russell Siebert tweet media
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Drew Comments
Drew Comments@sjs856·
I’m going to say this as plainly as possible @BretWeinstein. There is no way for the mRNA vaccines to cause cancer. Happy to have a molecular biology discussion and explain this in depth, but your erroneous assertion has no basis in any known biology in this solar system.
Bret Weinstein@BretWeinstein

You’re lying, either to yourself, to us, or both. Many things cause cancer. The introduction of the mRNA shots in 2021 unleashed an unprecedented wave. You and other doctors need to come clean. People have an absolute right to know what was done to them. Remember your oath.

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Russell Siebert
Russell Siebert@RussellSiebert·
@SymoneBeez Old school DVD of the little Einsteins series was a God-send for us. 2 am crying/sick. Pop it on and they chill out and eventually fall asleep.
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Symoné B. Beez
Symoné B. Beez@SymoneBeez·
Idk what to get my bro and sis for a baby shower gifts.
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Russell Siebert
Russell Siebert@RussellSiebert·
@WallStreetApes Health Sharing companies are a good, not perfect, alternative. Several out there. We use Zion Health Sharing. $730/ month for family of 5 and $2500 deductible.
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Wall Street Apes
Wall Street Apes@WallStreetApes·
Board certified medical doctor says he no longer has health insurance for his family He says cheapest plan he could get for his family is $24,000 per year with a $5,000 deductible before anything is covered Even a doctor can’t see the benefit in health insurance anymore….
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