Sam Barritt

175 posts

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Sam Barritt

Sam Barritt

@SamBarrittYes

Runner-Scientist | Dibble Lab @ HMS

Katılım Kasım 2011
247 Takip Edilen200 Takipçiler
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University of Vermont
University of Vermont@uvmvermont·
UVM, partnering with @biolabs, will join an elite group of universities which currently house on-campus incubators, with the launch of a startup incubator for life science research at UVM’s Colchester facility. ⬇️ uvm.edu/news/ovpr/univ…
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The Arany lab
The Arany lab@AranyLab·
We think this one is groundbreaking: Do you wonder how #SGLT2 inhibitors protect from heart failure? We show that #empagliflozen directly activates PANK1, rate-limiting for CoA synthesis, in human hearts. You read it here first! biorxiv.org/content/10.110…
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KayLee Steiner, PhD
KayLee Steiner, PhD@steinerkaylee·
My first author paper from my thesis work has been uploaded to BioRxiv! We identified Mecr as important for T cell fitness in in vivo CRISPR screens. I have further worked with Mecr and am the first to show it regulates T cell function and metabolism. biorxiv.org/content/10.110…
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Puigserver Lab
Puigserver Lab@puigserver_lab·
New study from our lab and Hans Widlund in @CellReports mapping the metabolic routes of the sulfur amino acid cysteine establishing melanoma epigenetic states maintained by lysosome function, conferring resistance to ferroptosis and metastasis shorturl.at/29erU
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Delgoffe Lab
Delgoffe Lab@DelgoffeLab·
New preprint from the lab is online! The product of a stellar collaboration with @Muir_Lab, we explore a chemically defined physiologic media formulation based of the metabolite of tumor interstitial fluid (TIF, or “tumor juice”) and its effects on T cell function! A brief 🧵1/
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Gerta Hoxhaj Lab
Gerta Hoxhaj Lab@Gerta_Hoxhaj·
FOR THE LOVE OF PURINES: We are truly excited to share our latest work @CellPressNews on mapping the routes of purine nucleotide synthesis in vivo-De novo and Salvage Purine Synthesis Pathways Across Tissues and Tumors.cell.com/cell/fulltext/…
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DeNicola Lab
DeNicola Lab@LabDeNicola·
*New paper alert* I’m happy to share our latest study, out this week in @NatureComms. Led by former postdoc Nate Ward (who now leads his own lab at @MoffittNews), we asked how mitochondria cope with cystine starvation. nature.com/articles/s4146…
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Greg Timblin
Greg Timblin@gtimblin·
Updated preprint up - direct supplementation with the metabolic cofactor Coenzyme A reverses macrophage immunosuppression + promotes pro-inflammatory & anti-microbial macrophage phenotypes via positive influence on CoA-dependent glucose metabolism (1/x) biorxiv.org/content/10.110…
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Evan Lien
Evan Lien@eclien·
Happy to share the first preprint from the lab! We describe how extracellular lipid availability regulates a polyunsaturated fatty acid trafficking pathway in cancer cells that influences ferroptosis sensitivity. Check it out! 👇 biorxiv.org/content/10.110…
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Science Signaling
Science Signaling@scisignal·
A second-generation degrader of the enzyme AKT—a key supporter of cancer cell proliferation and survival—can deplete AKT and halts breast cancer cell growth, especially in cells with basal JNK kinase activity. @alex_toker @BIDMChealth scim.ag/6a1
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Naama Kanarek
Naama Kanarek@KanarekNaama·
***New Paper***** @KanarekLab: Is this early, aberrant erythroid differentiation induced by folate depletion part of a molecular mechanism of nutritional anemia? check it out - Out today in Science Advances science.org/doi/10.1126/sc…
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