Rahul Samant

Hey, if anyone is wrapping up their PhD and wants to apply for this with us, let us know! You would be working on our organoid screen for TDP-43! theaftd.org/wp-content/upl…

We are having a great time in Portugal with our #UbiquitinFunction group! After two days so far of networking, inspiring talks, and engaging discussions, we look forward to the next two days ahead, and celebrating with our Gala dinner tomorrow evening!

The ALS- and FTD-associated proteins annexin A11 and CHMP2B act sequentially in plasma membrane repair: Developmental Cell cell.com/developmental-…

The registration deadline for the yICSA Symposium in Salamanca has been extended to 20 July! Registration is free, but spots are limited — don’t miss the chance to join us for great science, networking & the yICSA community. Register now! 👇 yicsasalamanca.wordpress.com/registration/

We are looking for motivated postdocs to join our lab starting Spring 2027 to study the Hsp70 Chaperone Code and Proteostasis, see here for more details: trumanlab.org/open-positions

Finally out in @Cellcellpress! Proteins with long intrinsically disordered regions (IDRs) are prone to misfolding during protein synthesis. This is prevented by mRNA 3′UTRs that act as mRNA-based IDR chaperones. cell.com/cell/fulltext/…

Our latest study out in @MolecularCell explores how and why MHC class I is aberrantly targeted for degradation via the autophagy-lysosome pathway in pancreatic cancer. Congrats to postdoc extraordinaire @marineberquez for leading this study! @UCSFAnatomy @UCSFCancer

A next-generation HDAC6 inhibitor for amyotrophic lateral sclerosis and frontotemporal dementia: academic.oup.com/brain/article/…

Phosphorylation tunes p62 condensates to drive autophagic degradation of ubiquitinated proteins: link.springer.com/article/10.103…..

🚨 Registration is now open!🚨 Join us at the Young ICSA Symposium – Salamanca Edition 🇪🇸 📅 15–16 Sept 2026 📍 CIC Salamanca Early-career researchers in cellular senescence: connect, present your work & build collaborations. 🔗 yicsasalamanca.wordpress.com/registration/

The integrated stress response suppresses PINK1-dependent mitophagy by preserving mitochondrial import efficiency #mitochondria nature.com/articles/s4146…

Don’t throw this in the bin. Chuck it in the ocean. #KillTheTurtles

🟢Registration is now open for Senescel 2026 (Sept 16-18, Salamanca, Spain). Enjoy a fantastic lineup of international speakers on aging and cellular senescence at one of the liveliest university towns in Spain. senescel2026.org/registration/

📋If you have an advanced project ready for presentation at SENESCEL or @YicsaC, consider submitting the manuscript to @AgingJrnl for this special collection on Cellular Senescence.

Thrilled to share our new paper: SLC33A1 is the long-sought ER GSSG exporter, maintaining redox homeostasis in the ER. Huge congratulations to my co-first author @shanshanliu1218 and my PIs @KivancBirsoy and @HiteLabMSKCC for leading this work. nature.com/articles/s4155… 🧵 1/9

Years in the making: a detailed aging gene signature in mice and rats. >30 tissues, high Ns, multi-time points throughout the lifespan. >5000 samples in total. The data is accessible, so you check to see if your favorite gene is age-regulated. science.org/doi/10.1126/sc…

📢 Update: Our upcoming yICSA Webinar with Amina Abdul-Aziz has been rescheduled to May 22nd at 16:00 CEST. We look forward to hearing about her journey from leukemia research to senescence biology! us06web.zoom.us/meeting/regist…

Don't miss David Vilchez's #Proteostasis Consortium Seminar today (4pm UK time). Super story about why being a bit cold might be good for you (if you're a worm). proteostasisconsortium.com/seminars/ #aging #ageing #longevity

mtHsp70 chaperone converts mitochondrial proteostasis stress into impaired protein import | PNAS pnas.org/doi/10.1073/pn…

Now online! Senescence in cancer: Hallmarks, paradoxes, and therapeutic promise dlvr.it/TRwHzm