Simón Vidal

the amount of capital deployed in AI is 🍌. this can’t end well.

Levi's Stadium hosts the Super Bowl today. Next door? The viral substation behind the NFL's wildest injury theory. Can EMF from this substation contribute to soft tissue injuries? Let science settle this! $100K in research funding is live and the proposals are rolling in👇

@ArtirKel Good luck making iPSC with chemicals :)

Two years ago I was very much a CGT maximalist, but now I have come around and "small molecules good actually", and what one can do with them remains to be fully explored. (re oral PCSK9i, oral GLP1s, and making iPSCs with just chemicals, no nucleic acids required)

@rust_ruslan @Google This is indeed pretty cool! I can’t wait to see for more people to use it!

That’s so cool! Can’t wait to try it: PaperBanana:Automating Academic Illustration for AI Scientists by @Google

@eurofounder Congrats to your daughter! It seems like a great accomplishment and seems to want to be independent and be proud. Do you even talk to your daughter to check what’s going on on her life?

My daughter got an offer from Google for a summer internship in California "They will pay me $12,000 per month" she was so excited While the whole family was celebrating, I excused myself I locked myself in a toilet and called Google's HR "My daughter received an internship offer from you, but there must be a mistake" I said The HR woman insisted this salary was standard for engineering interns "No company pays a young woman that much without expecting something in return. Do you want to prostitute my daughter?" I raised my voice She went quiet "Who are you again?" she asked I told her to withdraw the offer immediately My daughter found out three days later and hasn't spoken to me since I already sent her CV to Siemens and SAP, respectable technology companies, much bigger than Google She'll thank me when she's older

@Andrei_Tarkhov You really think you can write a pipeline 10x faster than an AI assistant? :)

compbio is about to die. A popular general-purpose AI assistant is already able to write a whole analysis pipeline starting from a simple prompt and a link to the data. Surely, I can do it 10 times faster and using 10 times fewer lines of code, but still “if it works, it works”

Yep. I thought the same when I watched this! I mean probably by the “outside” you would think that our body ages at the same rate but when you look at the organ or cellular level this is completely not true!

This is very cool! People should the lead on this. 100k funding!!

⭐ Do you have a bold idea you are excited about but never had the funding to try? ⭐ I am super excited to share that we are launching FIVE pilot funding grants for junior researchers across some of the most exciting areas in biomedical research with @ResearchHub & @ResearchHubF. So, if you are working in genomics, aging, neuroscience, AI vascular biology or related areas, this is a great opportunity to start 2026 with something independent! This round includes five separate grants (super easy to apply!). Each is meant to help you try out something new, re-analyze existing data, or launch a side project that could grow into something bigger. We have available funding for: • Aging and Longevity research. $10'000 • Vascular Biology. $10'000 • Neuroscience. $10'000 • Genomics and Proteomics. $5'000 • AI Tools and AI Agents for Biomedical Research. $5'000 Deadline: Applications close February 15, 2026. Application details are in the comments! If you have been waiting for a low barrier way to test a bold idea or explore a new direction, this is exactly that kind of projects we like to support with @ResearchHub & @ResearchHubF. Please share it among your network!

Enjoy a new perspective from our team at Altos labs about anti-aging and rejuvenation approaches! cell.com/cell-stem-cell…

including drugs for macular degeneration and skin disease using allogeneic and autologous cell-based gene therapies. Hopefully 2026 brings in more approvals specifically around new modalities!

While small molecules and proteins still lead the way, new modalities are gaining momentum, specifically cell and gene therapies and vaccines, which saw eight approvals

Despite FDA budget cuts and reorganization under the Trump administration, 46 new drugs were approved in 2025. nature.com/articles/d4157…

@nabsicle Gene editing + stem cells ;)

It always comes back to this question: “How do we cheat aging without changing my lifestyle?”

@davidasinclair @paulg Dude bitcoin!!

@paulg invest Apple hold

Neural nets work.

My two cents: in 2018 you were fat. In 2025 you look that lost weight and you dyed your hair, but actually look good. In 2023 you looked horrible. But hard to tell that you look better than all of the people your age. My gut feeling is that there are a lot of people out there that look as good as you but with a much easier life style

I’m going to try and achieve immortality by 2039. One year of time passes and I remain the same biological age. I invite you to join me. The search for the fountain of youth is the oldest story ever told. It’s been the dream of dreamers for millennia but always painfully out of reach. For the first time in the history of life on earth, in just the past 24 months, the window has opened for a conscious being to realistically strive for this goal. It is an absolutely insane moment. We currently do not know how 2039 immortality will be achieved. There are new, promising therapies that can turn back the clock decades, but they’re buggy. Sometimes they mistakenly cause cancer. We gotta fix that. But we know immortality is possible because nature has already solved it. This isn’t a physics problem like trying to travel faster than the speed of light, it’s a biological engineering problem that evolution has cracked multiple times. The freshwater hydra constantly regenerates its own cells and doesn’t succumb to senescence. It is effectively ageless. The "immortal jellyfish" (Turritopsis dohrnii) can revert its cells back to a youthful state and restart its life cycle indefinitely. Lobsters produce an especially active form of an enzyme called telomerase that preserves their telomeres and keeps their DNA from degrading as they age. We need to port the software to humans. 2039 is a reasonable target because of the accelerated, AI-driven rate of innovation. AI is morphing from assistant to scientist.  It is powering current researchers with previously unimagined capabilities to enhance discovery and development. That, coupled with enhanced biomarker measurement, creates a closed-loop system of improvement that will speed things up dramatically. This is what I’ve been doing for six years. As crude as longevity technology is today, the improvements I’ve personally seen are stunning. I started as a worn-down, inflamed, aged 42 year old who’d broken himself on the rocks of American food slop and entrepreneurship martyrdom. Six years later, my body largely operates at elite 18 year old levels. That includes my cardiovascular system, fertility, strength, and hormones. Not all is well though. I have mild to moderate hearing loss in my left ear that we can’t fix and my brain is anatomically age 42 (I’m 48). Still, unreal results. My team and I did this by following the scientific method. We measured the biological age of every organ. We referenced the best scientific evidence on how to slow aging and rejuvenate.  We methodically completed these protocols and measured again. Rinse and repeat. We could do so much more and faster if we had better measurement and better therapies. Both of which are cooking all over the world right now. To speed things up now, I’m currently having thousands of Bryan Johnson organ clones built in a dish. This will allow me to test drugs and other molecules against my biology to accelerate learning and save my body from potential mishaps. Yes, we’ll make mistakes. Hopefully they won’t be fatal. And of course there’s always bad luck to contend with. But I trust in fate and I believe that destiny is going to grant the human race the pleasure of achieving the ultimate: immortality. While immortality would certainly be cool, the real (secret) objective is to focus our collective attention on a positive goal. Something that helps us feel hope and excitement for the future. I personally love the idea of having a child-like mind, 18-year-old physical vibrancy, and a lifetime of wisdom. This 2039 goal is as much about AI as it is about us humans. It’s about how we survive giving birth to superintelligence. It’s kind of a big deal. We haven’t done it before. A lot can go wrong. I figure that one of the best ways to improve the probability that we build safe AI, and don’t kill each other in the meantime, is to transform our shared aspirations from yolo to don’t die. Right now, we are a suicidal species. We do all kinds of really primitive shit. We unnecessarily kill ourselves with what we eat and how we live our lives. Companies make profits from killing other people with their products. We trash the only home we have. We celebrate these things as virtue.  It’s really fucked up and backward. Soon enough we’ll realize just how infantile we are right now. The 2039 goal points us in the right direction. To say yes to life and no to death. Defiance even. If you’re interested in doing this with me, I’ll continue to share everything I do for free. I’m also going to build this out in Blueprint. We’ll help you do exactly what I’m doing, at a fraction of the cost and effort, alongside an aligned and motivated community. I think this is the coolest goal imaginable. I find it hard to believe that of all the people who’ve lived, it’s us who get the opportunity to have this moment. I pray that we have the courage to appreciate the sacredness of our existence. I pray that we will be brave enough to defend her amidst the onslaught of all the forces that would try to end her. We don’t know, but we may be the only intelligent life to exist in our corner of the galaxy. I pray we will be warriors, caretakers and stewards of existence and honor the gift that has been bestowed on us.

A full day of discussions and networking left everyone energized and aligned on building better, faster and more open science. Thank you to everyone who joined us for SciCon 2025. See you at the next edition!

Congrats to team Altos for the generalist prize! arcinstitute.org/news/virtual-c…

@bryan_johnson I reduced microplastics in my sperm by 85% and “I think” it was the dry sauna. LOL

I reduced microplastics in my sperm by 85% and I think it was the dry sauna