David Solecki (pronounced so_lets_ki 😉)

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David Solecki (pronounced so_lets_ki 😉)

David Solecki (pronounced so_lets_ki 😉)

@So_lets_kiLab70

Posting our lab life studying the neuronal cytoskeleton and chromatin with cool microscopes🔬Proud #GenX, #firstgen college, #intj @RITscience @stonybrooku Alum

Memphis via Buffalo & NYC Katılım Eylül 2019
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David Solecki (pronounced so_lets_ki 😉)
David Solecki (pronounced so_lets_ki 😉)@So_lets_kiLab70·
Forget #MicroscopyMonday or #FluorescenceFriday — it’s #TrailblazingTuesday! The lab’s latest flex: a live-cell imaging probe catching Ser2-phosphorylated RNA Pol II CTD dynamics in real time. Watch transcriptional elongation light up living nuclei! Bonus: Yours truly was hands-on with the knobs! Check out this stunning short video of Pol II puncta scanning a cell’s nucleus. What’s the coolest thing you’ve seen under a microscope? Drop it in the replies! #Science #scicomm #CellBio #sciart
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David Solecki (pronounced so_lets_ki 😉)
David Solecki (pronounced so_lets_ki 😉)@So_lets_kiLab70·
@pablo_jack It's probably a road to what we need to know: what is the actual par complex stoichiometry inside living cells. We are definitely not there yet as a field and there are situations where the different par complex components have non-complex functions that are a fronteir.
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David Solecki (pronounced so_lets_ki 😉)
David Solecki (pronounced so_lets_ki 😉)@So_lets_kiLab70·
What if you could watch chromatin states change inside living neurons.....IN REAL TIME? Repost or share if you or someone you know dreams of this! The Solecki Lab is building an imaging-based biosensor platform to make chromatin biology visible, measurable, and experimentally testable as neurons mature and wire into brain circuits (see enhancer nucleosomes fluttering below). We’re looking for an Associate Scientist who wants to do more than run experiments. Someone who wants to help build the framework for seeing how the neuronal genome changes as the brain is built.
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David Solecki (pronounced so_lets_ki 😉) retweetledi
DevelopmentalNeurobiologist
DevelopmentalNeurobiologist@DevelopmentalN·
This is some sci-fi level cell biology and neuroscience 🤯
David Solecki (pronounced so_lets_ki 😉)@So_lets_kiLab70

What if you could watch chromatin states change inside living neurons.....IN REAL TIME? Repost or share if you or someone you know dreams of this! The Solecki Lab is building an imaging-based biosensor platform to make chromatin biology visible, measurable, and experimentally testable as neurons mature and wire into brain circuits (see enhancer nucleosomes fluttering below). We’re looking for an Associate Scientist who wants to do more than run experiments. Someone who wants to help build the framework for seeing how the neuronal genome changes as the brain is built.

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David Solecki (pronounced so_lets_ki 😉) retweetledi
Anders Sejr Hansen
Anders Sejr Hansen@Anders_S_Hansen·
(1/16) Our 3-lab collab (Mirny & Zechner) led by Harvey, Henrik & Jack is out: Q: How do enhancers & promoters interact in space (contact vs. action-at-a-distance) and time (stable vs. transient)? A: Transient E-P contact (~25-42 nm lasting ~10-20 sec): biorxiv.org/content/10.648…
Anders Sejr Hansen tweet media
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David Solecki (pronounced so_lets_ki 😉)
David Solecki (pronounced so_lets_ki 😉)@So_lets_kiLab70·
@ShorterLab Oh man….hope you get to drive through those local winding roads in the Tuscan mountains. I drove from Como to a conference at that venue two years ago and there are some amazing old villages off the beaten path that are spectacular to see.
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ShorterLab
ShorterLab@ShorterLab·
Renaissance Tuscany Il Ciocco
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Barga, Toscana 🇮🇹 Italiano
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Tjian + Darzacq Group
Tjian + Darzacq Group@TjianDarzacq·
Out now in Science! Our new study challenges long-standing assumptions about transcription factor specificity in eukaryotes. Novel single-molecule measurements of TF behavior in living cells reveal an independence of locus-specific binding from DNA sequence recognition.🧵 science.org/doi/10.1126/sc…
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David Solecki (pronounced so_lets_ki 😉)
David Solecki (pronounced so_lets_ki 😉)@So_lets_kiLab70·
Still one of the purest dopamine hits in science: Thank you for your submission. For one brief, beautiful moment… the paper is someone else’s problem. Reviewer 2 can cook me later. 🔥
David Solecki (pronounced so_lets_ki 😉) tweet media
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David Solecki (pronounced so_lets_ki 😉)
David Solecki (pronounced so_lets_ki 😉)@So_lets_kiLab70·
Post-graduation jaunt through Santa Fe country. Beautiful enough to make you forget the altitude for a minute. Rattler skin reminder of who really runs the joint 😳
David Solecki (pronounced so_lets_ki 😉) tweet mediaDavid Solecki (pronounced so_lets_ki 😉) tweet mediaDavid Solecki (pronounced so_lets_ki 😉) tweet mediaDavid Solecki (pronounced so_lets_ki 😉) tweet media
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A@AschleighJ·
@So_lets_kiLab70 would you live there if you could live anywhere ?
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David Solecki (pronounced so_lets_ki 😉) retweetledi
kuba sędziński
kuba sędziński@ksedzinski·
💥 🚀 New preprint! 🎉🥳 How do hundreds of organelles organize themselves into near-perfect patterns inside a cell, without a blueprint? We dive deep into how basal bodies (BBs) self-organize in MCCs - and how actin actively tunes their dynamics into order 🍪 🧵👇 (1/17)
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David Solecki (pronounced so_lets_ki 😉) retweetledi
David Solecki (pronounced so_lets_ki 😉)
David Solecki (pronounced so_lets_ki 😉)@So_lets_kiLab70·
Mind-blowing cell action alert! Watching vesicle cargo lanes light up like a @FedEx highway in real-time under the #microscope. Who knew that home-brewed phosphatidic acid live cell imaging probe would look so stunning in human fibroblasts? Which organelle do you think its labeling? Drop your guess below! Too late for #FluorescenceFriday but just in time for #MicroscopyMonday #scicomm #sciart #Science
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Keşfet

@Yo_Hey_Kono @JCellBiol @pablo_jack @ShorterLab @AschleighJ @LiorKir @FedEx @elonmusk