Dr Murphy WeightLoss

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Dr Murphy WeightLoss

Dr Murphy WeightLoss

@TakeWeightOffMD

Board-certified: Internist, Obesity Med. Geneticist, RegenMed, Orthobiologist and DPC practice. Pro Paleo Doc! Author and Longevity Doc. using rapamycin etc.

Greenwich CT Katılım Şubat 2012
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Dr Murphy WeightLoss
Dr Murphy WeightLoss@TakeWeightOffMD·
Does this care in 2 degree weather not deserve to be reimbursed? Should record profit insurers be allowed to stiff labs, nurses and doctors & get away with it Scot-Free? We’ll see @EdGainesIII @wendellpotter @mass_marion We’ll see….
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Raffaele Di Giacomo, PhD
While interesting, such findings highlight the complexity of metabolic pathways and the role of NAD+ beyond simple aging paradigms. It begs us to ponder the nuances of NAD+ in cellular resilience and healthspan. Could there be specific conditions or biomarkers that might reveal a more complex interaction of NAD+ with age-related changes? Curious if you or others found similar results or potential confounding factors. #Metabolism #Research For more insights, Sci-Quest is a one-stop platform for your biomedical questions, capable of generating comprehensive reviews: [sciqst.com](sciqst.com).
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PeptideProSource
PeptideProSource@PeptideProSrc·
This is going to get screenshot and shared a thousand times without anyone reading past the headline. They measured whole blood. Red blood cells dominate whole blood NAD+ and they’re basically just a storage pool, they don’t reflect what’s happening in your tissues. When researchers actually biopsy skeletal muscle, the decline is real and documented — older adults show meaningfully lower muscle NAD+ than younger ones, and physically impaired older adults drop even further. The mechanism is NAMPT, the rate-limiting enzyme that drives NAD+ synthesis, and it falls roughly 35% in skeletal muscle between ages 20 and 70. Whole blood was always the wrong measurement. The study isn’t wrong, it’s just answering a question nobody was actually asking.
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AJ Juliani
AJ Juliani@ajjuliani·
Student turns in a paper. Send it to AI, generate a 5 question quiz on the content. Student takes the quiz next day on their own paper. If they wrote it, easy. If they didn't, obvious. No detection software. No accusations. Just quiet accountability.
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Sandeep Palakodeti, MD MPH
Let me explain how this works in real life A PHQ2 score is collected on almost every patient that walks in the door of a primary care clinic. At best, a PHQ9 Posted both here for your viewing pleasure TWO questions asked ONE time and MDD is “likely”. 9 questions seals it
Sandeep Palakodeti, MD MPH tweet mediaSandeep Palakodeti, MD MPH tweet media
Sandeep Palakodeti, MD MPH@DrDeepMD

@john_malone It’s not malpractice when all the professional society guidelines say to prescribe after a 2 (at best 9) question survey that basically anyone would test “positive” for on any moderately tough day “But judge, that’s what the gUiDeLiNeS say” Case dismissed

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ThePeptideList
ThePeptideList@PeptideList·
Tell him to start semaglutide. Inform him it is in nationwide shortage. Invite him to source it through a compounding pharmacy. Watch as he loses forty pounds over six months. Then tell him he can no longer access it… because the shortage has ended.
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Alina Chan
Alina Chan@Ayjchan·
World Health Organization director general told @nytimes that officials emphasized close contact as the way hantavirus spreads to avoid panicking people over occasional instances when transmission occurs without close contact. He said @WHO did not rely on the study of the 2018 Andes outbreak because it had not been "replicated." The virologist who conducted the study disagreed, saying their paper defines what the virus can do under favorable transmission conditions and public health guidance must account for this.
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Dr. Ammous
Dr. Ammous@AmmousMD·
Doctors don't read studies. In primary care alone, more than 4000 papers are published monthly. Doctors rely on guideline committees to interpret the evidence. Those committees are strongly funded by pharma.
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Sandeep Palakodeti, MD MPH
If you’re railing at the peptide bros for unproven interventions Please show the “data” on 20+ consecutive years of being on these meds, as we put folks on during teens/early 20s and leave them on for life No one has any real moral high ground Everyone is just vibing
Sandeep Palakodeti, MD MPH@DrDeepMD

1 in 3 college aged kids being on psych meds is absolutely bonkers We’ve completely lost the plot

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Michael Lin, MD PhD 🧬
Michael Lin, MD PhD 🧬@michaelzlin·
Ensitrelvir succeeded where Paxlovid had failed to show efficacy, in post exposure prophylaxis. It’s also been known for years that it prevents severe late disease in those already symptomatic as well as Paxlovid. Ensitrelvir should have been approved long ago. If it were from an American rather than Japanese pharma, it would have been.
nature@Nature

An antiviral pill has, for the first time, been shown to prevent COVID-19 in people exposed to the SARS-CoV-2 virus go.nature.com/4nAMi6g

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LandonTengwall
LandonTengwall@LandonTengwall·
20k on YouTube! Appreciate you guys for supporting me! Can’t wait for the Season
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Jay Anderson
Jay Anderson@TheProjectUnity·
Big Tech CEO found dead in her car after frantically calling her family telling them "We are in the matrix" after attending a series of high-tech related meetings and private conferences in California Erin Valenti was a tech entrepreneur and CEO of a company called Tinker Ventures. She tragically passed away in October 2019 under mysterious circumstances. Before her death, she made a series of frantic and confusing phone calls to her family, during which she reportedly said, "It's all a game, it's a thought experiment, we’re in the Matrix." Erin Valenti had been attending a series of tech-related meetings and conferences in California before she went missing. She was found dead in her rental car in San Jose, California, five days after she was reported missing. The official cause of death was determined to be "acute manic episode," but the circumstances surrounding her death and her strange final messages have led to a great deal of speculation and concern within the tech community and beyond. What did she mean?
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On The Pen™
On The Pen™@ManOnThePen·
Honest critique of med twitter, the problem with most docs is that no one is willing to be proven wrong anymore. Everything is pure tribalism and nothing can ever shift them from their foundational beliefs, or their entire world view crumbles… or their entire livelihood. There are real world consequences to you choosing to be so dogmatic.
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Cheryl Josie
Cheryl Josie@cheryl_josie·
Everyone who has ever had Covid is permanently damaged. ‘Long ‘COVID’ affects us all.
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Harry Spoelstra@HarrySpoelstra

Endothelial dysfunction and metabolic biomarkers in post-COVID-19 syndrome 🚨A nightmare study for many! FOR EVERYBODY: 9 months after your COVID-19, your blood vessels are STILL damaged, with probably biomarkers to prove it! 1. Study design: German prospective cohort (n=262 adults) compared blood biomarkers ~37 weeks post-SARS-CoV-2 infection (PCS patients + recovered) versus uninfected controls. 2. Endothelial dysfunction: - Soluble thrombomodulin (sTM) and lactate dehydrogenase (LDH), two established markers of endothelial (blood-vessel) damage, were significantly elevated in the combined infected group (UOC PCS + LIFE Cov+) versus never-infected controls. - So, previously infected individuals had significantly higher soluble thrombomodulin (TM) and lactate dehydrogenase (LDH), independent of PCS diagnosis or fatigue severity. - Critically, there were no significant differences between the PCS group and the LIFE Cov+ group for these markers. 3. Metabolic disruption: - Clear alterations in arginine biosynthesis and taurine/hypotaurine pathways, indicating impaired nitric-oxide (NO) metabolism with reduced L-arginine and taurine levels. →In plain terms: the vascular damage signal was just as strong in the symptom-free recovered people as in those still suffering from fatigue and other PCS complaints. The same held for the metabolic disruptions (impaired arginine biosynthesis and taurine/hypotaurine pathways linked to nitric-oxide production). 4. Fatigue-specific signal: - High-fatigue PCS patients (top MFI-20 quartile) showed elevated linoleic acid (LA) plus monounsaturated fatty acids oleic (OA) and palmitoleic (PA). →The fatty-acid signature specific to high-fatigue PCS adds a potential severity marker. 5. Notes: - Changes persisted already up to 9 months after infection. - PCS remains symptom-based, but these markers offer objective, measurable signals of underlying vascular and metabolic damage! -The discussion and results treat the observed endothelial and metabolic changes as consequences of a single infection and do not speculate on additive damage from subsequent exposures. - Limitations well noted. ‼️So, COVID-19 leaves detectable, objective blood-vessel and metabolic damage in the bloodstream nearly a year later, even if you feel completely fine and never had Long COVID symptoms. Specific fatty-acid spikes flag severe post-COVID fatigue. The “it’s all in your head” narrative for many post-covid people is directly contradicted by these biomarkers! These findings, solidly backed by prior 2021–2025 evidence, prove that COVID-19 inflicts measurable, persistent endothelial and nitric-oxide metabolic damage up to nearly a year later, even in fully symptom-free survivors, thereby supporting the implementation of routine biomarker screening, but even more importantly: #AvoidSars2 #AvoidReinfections. YOU ARE NOW A CV RISK PATIENT! nature.com/articles/s4159…

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tern@1goodtern·
Almost no one reading this needs to be worried about catching hantavirus tomorrow. But every person dealing with this outbreak needs to be on 100% vigilance with utmost best practice. Most people: don't need to be concerned. Experts: need to be extremely concerned.
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Hiroshi Yasuda (保田浩志)
"An antiviral pill has, for the first time, been shown to prevent COVID-19 in people exposed to the SARS-CoV-2 virus at home.. The drug, called ensitrelvir, is made by the Japanese pharmaceutical company Shionogi.. In an international study of more than 2,000 household contacts conducted from June 2023 to September 2024, about 9% of people who got a placebo within 72 hours of a housemate developing symptoms became symptomatic themselves, compared with only about 3% of those who got a five-day course of ensitrelvir. Rates of viral transmission were lower in the ensitrelvir group, too: confirmed infections, symptomatic or not, turned up in only 14.0% of those who received the drug, compared with 21.5% of those who got a placebo.." Not bad. 'At last, a pill that can prevent COVID after exposure to infected people' nature.com/articles/d4158…
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