Hua Bai

New publication from the lab @pnas . With the collaboration of Dr. Ping Kang @pingkang0, we uncovered how developmental NF-kB signaling links developmental timing (time to maturity) to lifespan😊😊pnas.org/doi/10.1073/pn…

Albumin in urine, even as low as 1.1mg/mmol, is an independent risk factor for cardiovascular diseases , even in healthy individuals without any other risk factors such as diabetes etc

How do mitochondrial ribosomes keep pace with membrane insertion? We address this question in our paper “Membrane insertion of mitochondrial-encoded proteins regulates ribosome decoding speed,” now out in Nature Structural & Molecular Biology (Link).

@sadagurski Congratulations 🎉🎊

I am thrilled to announce I have received the American Federation for Aging Research’s 2026 Vincent Cristofalo Rising Star Award in Aging Research. Learn more here: bit.ly/4tbnFhm.

I wrote this piece to promote thoughtful, respectful, and rational engagement with controversial science topics. I hope it fosters constructive dialogue in the scientific community—thank you for reading and sharing 🙏🏼 @NatRevImmunol nature.com/articles/s4157…

Yale Prof. Akiko Iwasaki writing in Nature: "Our inability to remain open and engage in rational discussions about controversial subjects may be eroding public trust in science." "I remember a colleague whose daughter developed a life-threatening autoimmune encephalitis after receiving the human papillomavirus (HPV) vaccine. I watched her struggle with obstacles in even asking whether her daughter’s illness might be linked to the vaccine. These questions are not only unwelcome in the field but also could jeopardize one’s career and credibility." "The pressure to stay within the consensus view is at an all-time high, for fear of reputational damage, funding exclusion and lack of career promotion, which is amplified at a massive scale on social media. However, there are broader epistemic consequences to staying within the consensus and suppressing alternative viewpoints, which could undermine trust and progress in science." "scientists are unable to freely inquire about the risk of [post-vaccine syndrome] without being labelled as ‘anti-vaxxers’." "True scientific progress depends on a culture that protects dissent"

Imaging-derived biological age across multiple organs links to mortality and aging-related health outcomes nature.com/articles/s4151…

🗞️📸🌟🤩Beautiful work led by @BernhardDumoul1 with the team builds a single cell spatial atlas of human DKD using Xenium + CosMx + snRNA-seq. @Nature This is not incremental. This is a new layer of pathology. Diabetic kidney disease (DKD) is still treated as one disease. That is the problem. Patients look similar clinically but behave very differently. We asked: is there a biologically distinct subgroup we are missing? rdcu.be/ff6ZZ

Large-scale CSF and plasma proteomics reveal immune, synaptic, and extracellular matrix disruptions across neurodegenerative diseases cell.com/neuron/fulltex…

U.S. President Donald Trump has fired all 24 members of the National Science Board, the body that oversees the National Science Foundation. Many science advocates see it as the latest step by his administration to erode—some would say destroy—the independence of the 76-year-old research agency. scim.ag/4eGM0YS

手指操，每天动动总是好的

Anthropic 官方团队亲自演示了 Claude Code 的正确打开方式，这才是真正的高阶用法。 全程仅需30分钟，而且完全免费，主讲人就是 Claude Code 的核心开发者。 一定要去看这场工作坊，建议直接收藏。 它带来的价值，远比那些标价几百美元的付费课程要高得多。 你平时也在用 Claude，但大概率还不知道它藏着40个实用指令。

@WalterWChen1 @UTSWMedCenter Congratulations 🎊

Thrilled to share that I’ll be starting my lab as an Assistant Professor and Endowed Scholar in @UTSWMedCenter Molecular Biology Dept this Fall! 🥳 We’ll study #peroxisomes #mitochondria #metabolism via the lens of neonatology👶🏻, a very exciting frontier in medicine! #neotwitter

Nature research paper: A spatial atlas of the healthy human liver from live donors go.nature.com/4sFMC4D

Effective fat burning exercises.

Congrats to @IsnardPierre1 and Marco Pontoglio HNF1B integrates signals in a feed-forward loop driving kidney disease progression | Happy to have contributed with Jon Levinsohn @ScienceMagazine science.org/doi/10.1126/sc…

Thread: Multi-omics sounds cool—until you actually try it. Here's are the nuances. 1/ You’ve got RNA-seq. Methylation. Proteomics. Time to “integrate” the data. But how? And why? Let’s break it down.

Years in the making: a detailed aging gene signature in mice and rats. >30 tissues, high Ns, multi-time points throughout the lifespan. >5000 samples in total. The data is accessible, so you check to see if your favorite gene is age-regulated. science.org/doi/10.1126/sc…

Polyunsaturated lipids kill senescent cells by ferroptosis cell.com/cell-metabolis…

这些老祖宗传下来的养生智慧真的太香了！ 网友整理的24个中药之最，把各种小毛病的“克星”都给扒出来了： 南瓜子护前列腺、玉米须排结石、山楂降血脂、酸枣仁助睡眠… 全是日常能吃到的东西，赶紧码住，养生不求人！

@kapahi_pankaj @ankurkumar110 Thank you PK😀

@TheBaiLab @ankurkumar110 Congratulations!!

New publication from the lab, led by the talented graduate student @ankurkumar110 , demonstrating that reduced plasmalogen ether lipid biosynthesis may contribute to age-dependent impairments of mitochondrial morphology and membrane dynamics. authors.elsevier.com/a/1mrba3Im5lHaF