@aideenryan1 @OAoise @olivertreacy1 @ThomasR55937842 @MichaelodwyerMD @Palleon_Pharma @DrPipDunne @hannahegan2 @NiamhLeonard5 @Galway_Reg_Med @AnastasiiijaW @eileenreidy111 @LarryEgan10 Looking forward to reading!!!
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Jacqui Shields
459 posts
Jacqui Shields
@Toastyjac
Science geek (@Shields_lab) | UoN BDI | terrible runner | sloooow biker
Katılım Mayıs 2016
401 Takip Edilen319 Takipçiler
@OAoise @olivertreacy1 @ThomasR55937842 @MichaelodwyerMD @Palleon_Pharma @DrPipDunne It was a team effort of fantatsic international experts & collaborators - @hannahegan2 @NiamhLeonard5 @Galway_Reg_Med @AnastasiiijaW @eileenreidy111 @LarryEgan10 Dr Nora Zakaria, Dr Shania Corry, Courtney Bull, Clodagh O'Meara, Dr Linda Howard, Prof Aisling Hogan, Prof Sean Hynes
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Our latest story on the impact of the Sia/Siglec axis and stromal cells in Colorectal cancer is online- led by @OAoise. We identified that stromal sialylation shapes innate immune phenotypes & function. @olivertreacy1 @ThomasR55937842 @MichaelodwyerMD @Palleon_Pharma @DrPipDunne
bioRxiv Cancer Bio@biorxiv_cancer
Stromal cells modulate innate immune cell phenotype and function in colorectal cancer via the Sialic acid/Siglec axis biorxiv.org/content/10.110… #biorxiv_cancer
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Jacqui Shields retweetledi
"How can integrating lymphoid tissues into biofabrication enhance 3D tumor models?
Our latest review explores how this approach could improve insights into tumor-immune interactions and cancer progression.
Read more here: sciencedirect.com/science/articl…
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Jacqui Shields retweetledi
In @Nature we use single cell multiomics, fibroblast fate tracing, and in vivo models to characterize immune fibroblast crosstalk in heart failure with @LavineLab @washumedicine, @Amgen , and @ImmunoFibHF nature.com/articles/s4158…
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📣I am very excited to announce that our lab is moving (very soon) to MD Anderson in Houston!
If you share our passion for #TME #CAF #metabolism, cutting-edge #MSproteomics, and are interested to join us for a postdoc, please contact me!
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12 years ago, @JNArnoldLab and I started groups in Cancer Cell Biology & Signalling section of King’s. Yesterday, we celebrated Professorships. Congrats, James! Thanks to all the students & staff in our labs that made this possible and all mentors that supported us along the way!
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Jacqui Shields retweetledi
📢 Hot off the press! CAFs are major regulators of the immune tumor microenvironment. In our new review we dissect a fascinating aspect of this regulation: CAF-induced physical constraints controlling T cell state and localization in solid tumours nature.com/articles/s4156…
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Jacqui Shields retweetledi
Fibroblasts and monocytes interact to mediate fibro-stenosis in #Crohns disease in this work from SMI member Gianluca Matteoli @gmatteoli1978 @JCI_insight
jci.org/articles/view/…
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Jacqui Shields retweetledi
Recipient tissue microenvironment determines developmental path of intestinal innate lymphoid progenitors.
Congrats to Paula Clark, @gogoimayuri, @Ana_CFF, @JaneDoesScience, @Shields_Lab & the Mckenzie Lab!!
PLZF+ ILCPs from the instestine!
disq.us/t/4qj9qde
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@aideenryan1 @DwyerLab @NiamhLeonard5 @eileenreidy111 @ShaniaMCorry @DrPipDunne @QubPGJCCR @MonashUni Congrats @aideenryan1! Looking forward to reading this 😊
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Congratulations to @NiamhLeonard5 on the publication of the final paper from her PhD in iScience. A truly collaborative effort @eileenreidy111 and @ShaniaMCorry @DrPipDunne @QubPGJCCR and Daniela Loessner @MonashUni
cell.com/iscience/fullt…
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@MariaPAlcolea @SCICambridge @PDN_Cambridge @GSkrupskelyte @J_E_Rojo Super exciting @MariaPAlcolea. Downloaded and ready to read!
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Did you know that not all newly forming tumours persist long-term? If you are intrigued to know what determines the survival of early tumours, check out our latest preprint! @SCICambridge, @PDN_Cambridge. Work led by @GSkrupskelyte and @ @J_E_Rojo 🧵1/8
biorxiv.org/cgi/content/sh…
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Promotion success!
"Professor Acton" - October 2024
Thank you @CRUKresearch, @ERC_Research, @wellcometrust for funding
Thank you @LMCB_UCL, @UCLLifeSciences for mentorship and support since 2016.
But above all, thank you to the amazing students and postdocs past and present
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Jacqui Shields retweetledi
Secure your spot now! Early Bird offer for #BMVBS24 meeting ends on 7th June. Register for #BMVBS24 and the separate Endothelial Glycocalyx symposium at shop.bris.ac.uk/conferences-an…
Thanks to all our sponsors including our most recent supporters @Co_Biologists @BritishHeartF
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Jacqui Shields retweetledi
Apply now! @EACRnews and The Mark Foundation have teamed up to support outstanding postdoctoral researchers in Europe with a 3-year fellowship. Deadline to apply is August 21, see the link for eligibility criteria.
EACR@EACRnews
Exciting news! Outline proposal submissions are now OPEN for EACR-@TheMarkFdn Postdoctoral Fellowships, supporting excellent postdoctoral researchers in laboratories throughout Europe. Learn more and submit by 21 August: eacr.org/eacr-fellowshi…
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Jacqui Shields retweetledi
Join the fully funded @nottm_bbsrc_dtp doctoral program for UK professionals to research biotechnology, pharmaceuticals, and environmental science. Drive innovation, create a lasting impact, and become a changemaker.
Change tomorrow, Apply by 6 May: nottingham.ac.uk/bbdtp/ pic.x.com/IUHZS9cbnO
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Jacqui Shields retweetledi
Join the fully funded @nottm_bbsrc_dtp doctoral program for UK professionals to conduct research in biotechnology, pharmaceuticals, and environmental science. Drive innovation, create a lasting impact, become a changemaker.
Change tomorrow, apply today: nottingham.ac.uk/bbdtp/
GIF
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Jacqui Shields retweetledi
I am pleased to share the final version of our Human Breast Cell Atlas with @MarioniLab now out @NatureGenet. There are important new additions, which I will leave to @Dr_SaraPensa and @AustinDReed to mention👇 . Couple of points i want to highlight 👇:
nature.com/articles/s4158…
Walid Khaled@WTKLAB
I am very pleased to share our second and largest contribution to “The Human Breast Cell Atlas” (HBCA) project. Buckle up a longish thread ahead! biorxiv.org/content/10.110…
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Jacqui Shields retweetledi
Online now! The loss of HAPLN1 in aged skin fibroblasts drives melanoma progression by increasing ICAM1 and angiogenesis. Blocking ICAM1 reduces tumor size. @ashaniTW @glo_rious @Yash_Chhabra (rdcu.be/dBaGo)
doi.org/10.1038/s43587…
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