Michael Webster

How photosynthetic genes are transcribed 🧬🌿 I’m really pleased to share the first work from my group at @JohnInnesCentre published today in @CellCellPress: cell.com/cell/fulltext/…

Super lucky to get the Faraday!@royalsociety Very grateful for the support from @JohnInnesCentre, @CarolineDeanLab, @DingLab_RNA, and all the collaborators/friends🙏jic.ac.uk/press-release/…

Excited to share our new preprint on co-transcriptional splicing! U1 snRNP is recruited to RNA polymerase II through multiple interaction sites, with elongation factor SPT6 binding directly to the U1 snRNP protein. biorxiv.org/content/10.110… #cryoEM #transcription #splicing

Inspiring example of structural prediction + evolutionary conservation analysis by @amiralito_ in this thread 👇

VACANCY - We have an exciting opportunity for a Cryo-electron Microscopy Support Specialist to join the Bioimaging Platform, collaborating with scientists at JIC and @NorwichResearch okt.to/si4roe Closing date - 14 February 2025 Contract - Full-time, indefinite

Please spread the word: we are looking for PhD students! Interested in supramolecular complexes in gene expression? Go to imcbio-phdprogram.unistra.fr scroll down to “Integrated Structural Biology (LabEx INRT)” for project descriptions and start application process by January 19th!

Also pleased to see evidence of the idea of increasing mRNA tension limiting translation as the machineries approach. An intricate mechanism to avoid molecular collisions 💥

Really pleased to see this study of gene expression coupling performed so comprehensively! When we determined structures of ribosome-polymerase complexes we knew were seeing the tip of the iceberg- static moments of two machines that should be seen moving. Congratulations!

Beautiful cryo-EM reconstructions from our lab neighbour. Delighted to see it out 👇🔬❄️🧬

In @ScienceMagazine - great collaborative work w/ @AlbertW_Lab & @RappsilberLab showing that bacterial RNA polymerase can thread nascent mRNA into the pioneering ribosome from two sides for higher translation initiation efficiency - target for antibiotics? eurekalert.org/news-releases/…

From #cryoEM to #singlemolecule kinetics science.org/doi/10.1126/sc… So proud and humble to share this work alongside @WebsterMichael0 and one of my scientific hero @AlbertW_Lab This is how I envision Science and Collaboration at its best. @NilsWalterLab

🌱 Exciting opportunity in the Jarvis Lab @OxfordBiology! We're hiring a 3-year Research Assistant to study the structure & function of the plant chloroplast protein import machinery. 🔬 Help us resolve the structure of the TOC-TIC translocon! Apply here: my.corehr.com/pls/uoxrecruit…

We are excited to share our latest work on the cooperation between RNA polymerase and the ribosome in bacteria: science.org/doi/10.1126/sc… The work was supported by @IGBMC, @Inserm, @CNRS, @unistra, @ERC_research, @IMC_Bio, and @instructhub. 1/7

PRESS RELEASE - Delivery mechanism discovery resolves gene expression puzzle International research collaboration has used advanced microscopy to capture in unprecedented detail a critical moment in gene expression. okt.to/ewgcsX @NorwichResearch @WebsterMichael0

Joe Ecker @JoeEcker, Joseph Swift @_joseph_swift, and team have revealed the genetic details of 30-million-year-old question: How did some plants evolve from less-efficient C3 photosynthesis to C4 photosynthesis? Their findings pave the way for the creation of more robust, efficient plants that withstand the effects of climate change and can feed a growing global population 🌱 @Nature salk.edu/news-release/s…

A few more days to apply 👇 Hopefully an exciting project for a student interested in cryo-EM, biochemistry, biophysics and plants 🪴

We are excited to announce the launch of our MSc in Microbiology, and I will be serving as the Program Director for the next academic year. Please feel free to reach out if you would like to learn more about this exciting opportunity. @biouea uea.ac.uk/course/postgra…

VACANCY - We're recruiting a Director to lead our world-renowned, independent, international centre of excellence in plant science, genetics and microbiology. Please share and apply: okt.to/kURnfW Closing date - 22 November 2024 @NorwichResearch

Great to see this #cryoEM collaboration between @JohnInnesCentre and @TheSainsburyLab out in its final form. Take a look if you're interested in the fascinating world of plant immunity structural biology.

We have an open #postdoc position to study the molecular mechanisms of #DNArepair !🧬🔬 The project will build on recent findings nature.com/articles/s4158… and established collaborations, using #cryoEM and #SingleMolecule imaging. Access to fantastic facilities @MRC_LMB .